Results 71 to 80 of about 2,028,198 (315)

Amyloid-β colocalizes with apolipoprotein B in absorptive cells of the small intestine

Lipids in Health and Disease, 2009
Background Amyloid-β is recognized as the major constituent of senile plaque found in subjects with Alzheimer's disease. However, there is increasing evidence that in a physiological context amyloid-β may serve as regulating apolipoprotein, primarily of ...
Dhaliwal Satvinder S, Pallebage-Gamarallage Menuka MS, Takechi Ryusuke, Galloway Susan, Mamo John CL   +4 more
doaj   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Effect of memantine on calcium signaling in hippocampal neurons cultured with β-amyloid [PDF]

, 2021
Vyacheslav M. Shkryl, V. V. Ganzha, E. A. Lukyanetz   +2 more
openalex   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Propylene Glycol induces Excessive Neurodegeneration in Combination with Amyloid Beta1-40 Toxin in Male Rat Hippocampus [PDF]

Journal of Basic Research in Medical Sciences
Introduction: Propylene glycol (PG) is frequently used as a solvent for various medications. However, there is substantial evidence of Propylene glycol toxicity, such as depression, agitation, and seizures, particularly when used in combination with ...
Sajjad Salari, Maryam Bagheri
doaj  

Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β

Journal of Neuroinflammation, 2011
Background Amyloid β (Aβ) accumulates in Alzheimer's disease (AD) brain. Microglial activation also occurs in AD, and this inflammatory response may contribute to disease progression.
Kauppinen Tiina M, Suh Sang, Higashi Youichirou, Berman Ari E, Escartin Carole, Won Seok, Wang Chao, Cho Seo-Hyun, Gan Li, Swanson Raymond A   +9 more
doaj   +1 more source

Insights into the Mechanisms of Oligomerization/Fibrilization of Amyloid β Peptide from Nuclear Magnetic Resonance

, 2022
Hidekazu Hiroaki
openalex   +2 more sources

Subtyping of circulating exosome-bound amyloid β reflects brain plaque deposition

Nature Communications, 2019
Despite intense interests in developing blood measurements of Alzheimer’s disease (AD), the progress has been confounded by limited sensitivity and poor correlation to brain pathology.
Carine Z. J. Lim, Yan Zhang, Yu Chen, Haitao Zhao, M. Stephenson, Nicholas R. Y. Ho, Yuan Chen, Jaehoon Chung, A. Reilhac, T. P. Loh, Christopher L H Chen, Huilin Shao   +11 more
semanticscholar   +1 more source