Results 221 to 230 of about 1,464,719 (336)

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

AI‐Assisted Customizable SERS‐Based Aptasensor for Label‐Free, Rapid, and Sensitive Detection of Tau: Comparative Analysis Using Random Forest and Convolutional Neural Networks

Analysis &Sensing, EarlyView.
A customizable SERS‐based aptasensor platform integrates aptamer‐functionalized gold nanoparticles with machine learning models (RF and CNN) to detect tau protein, a key biomarker for Alzheimer's disease. This rapid, label‐free detection system achieves a detection limit of 100 pM, enabling early diagnosis and monitoring of disease progression.
Farbod Ebrahimi, Farshad Ebrahimi, Anjali Kumari, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Sex differences in efficacy/safety of anti-amyloid-beta monoclonal antibodies for the treatment of Alzheimer's disease. [PDF]

Transl Clin Pharmacol
Lim S, Lee HW, Yoon S, Han JW, Chung JY, Yoon S.   +5 more
europepmc   +1 more source

Plant Proteins as Emulsifiers in the Food Industry: Research Progress, Current Challenges and Future Trends

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT The impressive growth in the global market for plant‐based foods has a direct impact on the food industry, requiring greater efforts in product reformulation for the replacement of animal‐based ingredients, including proteins. The replacement of animal‐derived proteins frequently applied as emulsifiers in food formulations, for example ...
Thais C. Brito‐Oliveira, Talita A. Comunian, Samantha C. Pinho   +2 more
wiley   +1 more source

Amyloid beta binding partners in the brain tissue of older adults. [PDF]

Alzheimers Dement
Oveisgharan S, Yu L, Wang Y, Yang J, Vialle R, Lopes KP, Tasaki S, Young-Pearse TL, De Jager PL, Petyuk VA, Schneider JA, Seyfried NT, Bennett DA.   +12 more
europepmc   +1 more source

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

Animal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao, Xingyuan Ma, Ping Tian, Lianbin Li, Zafir Muhammad, Xiaokun Wang, Xuemei Xue, Jinhe Xiao, Liangjun Zheng, F. A. El‐Gohary, Xin Zhao, Junning Pu, Huping Xue   +12 more
wiley   +1 more source

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source