Results 121 to 130 of about 384,012 (260)

Use of Technetium‐99m‐Pyrophosphate Single‐Photon Emission Computed Tomography/Computed Tomography in Monitoring Therapeutic Changes of Eplontersen in Patients With Hereditary Transthyretin Amyloid Cardiomyopathy

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease
Background Hereditary transthyretin amyloid cardiomyopathy (hATTR‐CM) is a progressive and fatal disease. Recent evidence indicates that bone scintigraphy may serve as a tool to monitor the effectiveness of hATTR‐CM treatment. The objective of this study
A. Yu, Yi-Chieh Chen, C. Tsai, Y. Wu, M. Su, C. Chou, C. Shun, Hsueh-Wen Hsueh, Jimmy Jyh-Ming Juang, Ming-Jen Lee, P. Tseng, Chia-Hua Hsu, S. Hsieh, Chi-Lun Ko, Mei-Fang Cheng, C. Chao, Yen-Hung Lin   +16 more
semanticscholar   +1 more source

The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases [PDF]

, 2014
Copyright © 2014 Al-Mahdawi, Anjomani Virmouni and Pook. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Al-Mahdawi, S, Pook, MA, Virmouni, SA
core   +1 more source

Amyloid Cardiomyopathy

JACC: CardioOncology, 2021
Roberta Shcolnik Szor, Aristoteles Alencar, Bruno Vaz Kerges Bueno, Caio Rebouças Fonseca Cafezeiro, Lucas Bassolli de Oliveira Alves, Ludhmila Abrahão Hajjar, Gracia Aparecida Martinez, Vanderson Rocha, Fabio Fernandes   +8 more
openaire   +1 more source

Acoramidis in Transthyretin Amyloid Cardiomyopathy

New England Journal of Medicine
To the Editor: In a phase 3 trial of acoramidis for transthyretin amyloid cardiomyopathy, Gillmore et al. (Jan. 11 issue)(1) used the Finkelstein-Schoenfeld test to assess the hierarchical composite primary outcome. They expressed the treatment effect as a win ratio, thereby following the initial presentation of the analysis of a prioritized outcome.(2)
VERBEECK, Johan, De Backer, Mickael, BUYSE, Marc   +2 more
openaire   +5 more sources

A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein [PDF]

, 2016
Prion diseases are rare neurodegenerative conditions associated with the conformational conversion of the cellular prion protein (PrPC) into PrPSc, a self-replicating isoform (prion) that accumulates in the central nervous system of affected individuals.
Biasini, Emiliano, Borsello, Tiziana, Castilla, Joaqu\uedn, Cerovic, Milica, Cimini, Sara, Elezgarai, Saioa R., Gobbi, Marco, Massignan, Tania, Moreno, Jorge, Negro, Alessandro, Nonno, Romolo, Restelli, Elena, Riccardi, Geraldina, Sangiovanni, Valeria, Stincardini, Claudia, Stravalaci, Matteo, Vanni, Ilaria   +16 more
core   +2 more sources

The multi-modality cardiac imaging approach to the Athlete's heart: an expert consensus of the European Association of Cardiovascular Imaging [PDF]

, 2015
The term 'athlete's heart' refers to a clinical picture characterized by a slow heart rate and enlargement of the heart. A multi-modality imaging approach to the athlete's heart aims to differentiate physiological changes due to intensive training in the
Abergel, Abhayaratna, Andersson, Angell, Bartram, Basavarajaiah, Blair, Bossone, Bruder, Caso, Chandra, Corrado, Corrado, D'Andrea, D'Andrea, D'Andrea, D'Andrea, D'Andrea, D'Andrea, D'Andrea, Di Paolo, Douglas, Estorch, Fagard, Fagard, Florescu, Gabrielli, Galderisi, Galderisi, Garber, George, Gilbert, Goldhammer, Grothues, Hauser, Hildick-Smith, Kalliokoski, Kim, Knutsen, La Gerche, La Gerche, Ljungqvist, Mahrholdt, Makan, Maron, Maron, Maron, Maron, Maron, Matsumura, Matsuo, Montgomery, Moon, Moon, Morganroth, Mousavi, Nagueh, Nottin, O'Hanlon, Pattynama, Payne, Pelliccia, Pelliccia, Petersen, Pluim, Prakken, Rehr, Richand, Rickers, Rudski, Saghir, Scharf, Scharhag, Schwartz, Semelka, Sen-Chowdhry, Sen-Chowdhry, Severino, Sharma, Shave, Shave, Spirito, Steinvil, Teramoto, Terry, Thomas, Urhausen, Vinereanu, Whyte, Wolfe, Zeppilli, Zoncu   +91 more
core   +4 more sources

Atrial Fibrillation as a Prognostic Factor for All-Cause Mortality in Patients With Transthyretin Amyloid Cardiomyopathy

JACC CardioOncology
Background Atrial fibrillation/atrial flutter (AF/AFL) are common manifestations of transthyretin amyloid cardiomyopathy (ATTR-CM) but have not been found to be predictive of mortality.
R. Witteles, John L Jefferies, S. Kapa, F. Cappelli, M. Sultan, B. Gundapaneni, Margot K Davis, P. García-Pavía   +7 more
semanticscholar   +1 more source

A Review of Tafamidis for the Treatment of Transthyretin-Related Amyloidosis [PDF]

, 2015
Transthyretin (TTR)-related amyloidosis (ATTR) is a devastating disease which affects a combination of organs including the heart and the peripheral nerves, and which has a fatal outcome if not treated within a average of 10 years.
Benson, Merril D., Waddington Cruz, Márcia   +1 more
core   +1 more source

Long‐term tafamidis efficacy in patients with transthyretin amyloid cardiomyopathy by baseline left ventricular ejection fraction

European Journal of Heart Failure
Patients with transthyretin amyloid cardiomyopathy (ATTR‐CM) present with diverse left ventricular ejection fraction (LVEF). This study assessed tafamidis efficacy by baseline LVEF in the phase 3 Tafamidis in Transthyretin Cardiomyopathy Clinical Trial ...
B. Drachman, T. Damy, M. Hanna, Ronnie Wang, F. Angeli, P. García-Pavía   +5 more
semanticscholar   +1 more source

Systemic amyloid A amyloidosis of the bladder after transurethral resection of urothelial carcinoma

IJU Case Reports
Introduction Amyloid A amyloidosis of the bladder is not a major disease. We report a patient with systemic amyloid A amyloidosis of the bladder after transurethral resection of urothelial carcinoma.
Kaori Yamashita, Keita Yoshida, Tadao Nakazawa, Satoshi Kubota, Takahiro Shiseki, Eri Sekido, Masashi Inui   +6 more
doaj   +1 more source