Results 51 to 60 of about 384,012 (260)

Technical Feasibility of Implementing and Commercializing a Machine Learning Model for Rare Disease Prediction

IEEE Access, 2023
Wild-type transthyretin amyloid cardiomyopathy is an under-recognized cause of heart failure. Pfizer previously developed a machine learning model that performed well in identifying wild-type transthyretin amyloid cardiomyopathy vs.
George Koutitas, Kimberly Nolen, Sepideh Attal, Anastasios Ventouris, Yinnon Dolev, Hans Thijs Van Den Broek   +5 more
doaj   +1 more source

Diagnosis of some diseases through biomarkers [PDF]

, 2019
Muchos gatos, como los perros, sufren de diferentes enfermedades. que en ese momento no permiten mostrar síntomas o signos que permiten identificar que la mascota sufre una enfermedad grave, ya que las características de los gatos son diferentes a las de
Gutiérrez Rodríguez, Andrea
core  

Small heat-shock proteins: important players in regulating cellular proteostasis [PDF]

, 2015
Small heat-shock proteins (sHsps) are a diverse family of intra-cellular molecular chaperone proteins that play a critical role in mitigating and preventing protein aggregation under stress conditions such as elevated temperature, oxidation and infection.
Carver, John A., Ecroyd, Heath, Meehan, Sarah, Treweek, Teresa M.   +3 more
core   +1 more source

NON-VAL30MET-TRANSTHYRETIN AMYLOID CARDIOMYOPATHY. LITERATURE REVIEW AND CLINICAL CASE

Российский кардиологический журнал, 2018
A literature review presented, with a clinical observation of non-Val30Mettransthyretin amyloid cardiomyopathy. Modern diagnostic and management algorithms discussed.
A. Ya. Gudkova, A. A. Poliakova, А. V. Amelin, O. М. Moiseeva, А. N. Krutikov, V. М. Tishkova, R. V. Grozov, D. V. Ryzhkova, T. V. Makurova, A. A. Kostareva, E. N. Semernin, E. V. Shlyakhto   +11 more
doaj   +1 more source

Description of rare clinical case of AA-amyloidosis with involvement in pathological process of heart and lungs

Инновационная медицина Кубани, 2020
Amyloidosis is a unique group of disorders caused by the insoluble protein fibers accumulation known as amyloid fibrils in extracellular tissue and organ spaces.
Z. G. Tatarintseva, E. D. Kosmacheva
doaj   +1 more source

Transthyretin cardiac amyloidosis: an under-diagnosed cause of heart failure [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2014
Introduction: Cardiac amyloidosis is the most common cause of infiltrative cardiomyopathy and is associated with a poor prognosis. Transthyretin cardiac amyloidosis, particularly the type caused by the mutation that replaces the amino acid valine with ...
Gabriela Molina O, Daniel Judge, Wayne Campbell, Harjit Chahal, Marc Mugmon   +4 more
doaj   +1 more source

Single-centre experience on transthyretin familial amyloid polyneuropathy : case series and literature review [PDF]

, 2018
Familial amyloid polyneuropathy (FAP) is a most often length-dependent axonal neuropathy, often part of a multisystem disorder also affecting other organs, such as cardiac, gastrointestinal, genitourinary, renal, meningeal and eye tissue.
De Bleecker, Jan, De Pauw, Michel, Martens, Broes   +2 more
core   +2 more sources

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

British Society of Echocardiography guideline for the transthoracic echocardiographic assessment of cardiac amyloidosis

Echo Research and Practice, 2023
These guidelines form an update of the BSE guideline protocol for the assessment of restrictive cardiomyopathy (Knight et al. in Echo Res Prac, 2013). Since the original recommendations were conceived in 2013, there has been an exponential rise in the ...
William E. Moody, Lauren Turvey-Haigh, Daniel Knight, Caroline J. Coats, Robert M. Cooper, Rebecca Schofield, Shaun Robinson, Allan Harkness, David L. Oxborough, Julian D. Gillmore, Carol Whelan, Daniel X. Augustine, Marianna Fontana, Richard P. Steeds   +13 more
doaj   +1 more source

Severe cardiac AL amyloidosis in an elderly patient with multiple SARS-CoV-2 reinfection: a case report

Российский кардиологический журнал, 2023
Introduction. The relationship between systemic amyloidosis and coronavirus disease 2019 (COVID-19) has not been sufficiently studied to date. This paper presents a case of the persistence of COVID-19 markers in an elderly patient with systemic ...
E. V. Reznik, T.L. Nguyen, O. A. Ettinger, V. An. Lazarev, S. V. Borisovskaya, A. I. Guseva, A. V. Salikov, G. N. Golukhov   +7 more
doaj   +1 more source