Results 61 to 70 of about 15,436 (169)

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He, Jingjing Zeng, Guoqing Wang, Yuxin Li, Feng Zhang   +4 more
wiley   +1 more source

Chronic, neutrophilic pericarditis with free‐floating intrapericardial mesothelial‐lined fibrous nodules in a cat

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 15‐year‐2‐month‐old, male, neutered domestic shorthair cat was presented for a 1‐week history of increased respiratory effort and declining appetite. Point‐of‐care ultrasound diagnosed tri‐cavitary effusion, and echocardiography revealed the presence of multiple free‐floating hyperechoic nodules within the pericardium.
Maximiliane Gabriele Sehn, Deepa Cavalli‐Sforza Guitart, Jonathan Williams, Victoria Lipscomb, Brogan Kim Atkinson   +4 more
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, Volume 36, Issue 6, November 2026.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Cardiac Resynchronization Therapy, Remodeling, and Outcome in Patients With Amyloid Transthyretin Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Transthyretin amyloid cardiomyopathy (ATTR‐CM) has a specific pathophysiology, with myocardial stiffening and systolic dysfunction only in advanced stages. We aimed to investigate the response to cardiac resynchronization therapy (CRT) in ATTR‐
Alberto Aimo, Martina Nesti, Giuseppe Vergaro, Ammar M. Killu, Dimitrios Bampatsias, Daniela Tomasoni, Cinzia Forleo, Francesco Musca, Matteo Serenelli, Julie Rosenthal, Sergio L. Teruya, Nader J. Al‐Shakarchi, Mariel S. Tameze, Vincenzo Castiglione, Alessio Nicolai, Giorgia Panichella, Riccardo Saro, Aldostefano Porcari, Giulio Sinigiani, Vera Fico, Elisa Frau, Reem Matar, Andrea I. Guaricci, Giacomo Tini, Alberto Cipriani, Maria B. Musumeci, Simone Longhi, Cristina Chimenti, Marco Metra, Martha Grogan, Federico Perfetto, Francesco Cappelli, Marco Merlo, Gianfranco Sinagra, Mathew S. Maurer, Ahmad Masri, Michele Emdin   +36 more
doaj   +1 more source

Mitral and tricuspid stenosis caused by light chain cardiac amyloid deposition

ESC Heart Failure, 2020
Cardiac amyloidosis results in an infiltrative restrictive cardiomyopathy, with a number of characteristic features: biventricular hypertrophy, abnormal myocardial global longitudinal strain with relative apical sparing, biatrial dilation, and small ...
Varinder K. Randhawa, Sneha Vakamudi, Dermot M. Phelan, Christy J. Samaras, Jesse K. McKenney, Mazen Hanna, Antonio L. Perez   +6 more
doaj   +1 more source

Vascular-variant cardiac amyloid: Cardiac MRI and histopathological appearances

Acta Radiologica Open
Cardiac amyloidosis is an infiltrative cardiomyopathy caused by the deposition of abnormally folded proteins within the myocardium. Several amyloid subtypes have been documented, with diagnosis supported by abnormal serum plasma electrophoresis ...
Sebastian Flynn, Kamal Fadalla, Aurelie Fabre, Jonathan D. Dodd   +3 more
doaj   +1 more source

Amyloid Deposits in Intramural Coronary Arteries of Feline Hearts: A Retrospective Histopathological Study

Journal of Molecular Pathology
Background: Amyloidosis involving the heart is one of the types of the disease recognized in humans and has been previously described in dogs. To date, no data regarding the presence of amyloid in cardiac tissues of a large group of feline patients have ...
Izabela Janus-Ziółkowska, Joanna Bubak, Ewa Sawińska, Marcin Nowak, Agnieszka Noszczyk-Nowak   +4 more
doaj   +1 more source

Microfibrillar cardiomyopathy: A rare case

Indian Journal of Pathology and Microbiology, 2011
Microfibrillar cardiomyopathy is a very rare cause of restrictive cardiomyopathy (RCM). The index case was a male patient who presented with shortness of breath and pedal edema. Further clinical investigations favored a clinical diagnosis of RCM.
Narender Kumar, Ruma Ray
doaj   +1 more source

Amyloid Cardiomyopathy

JACC: CardioOncology, 2021
Szor, Roberta Shcolnik, Alencar, Aristoteles, Bueno, Bruno Vaz Kerges, Cafezeiro, Caio Rebouças Fonseca, Alves, Lucas Bassolli de Oliveira, Hajjar, Ludhmila Abrahão, Martinez, Gracia Aparecida, Rocha, Vanderson, Fernandes, Fabio   +8 more
openaire   +2 more sources

Diagnosis of Wild-Type Transthyretin Cardiomyopathy and Initiation of Pathogenetic Therapy in an Elderly Patient: A Clinical Observation

Российский журнал гериатрической медицины
The article presents a case study of an 80-year-old patient with wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM). This case demonstrates the importance of comprehensive examination in cases of unexplained heart failure in elderly patients, and
E. E. Esenbekova, Z. A. Asatova, K. A. Eruslanova, A. Yu. Shchedrina, A. T. Shubina, E. A. Koroleva, T. A. Bondarenko, S. R. Gilyarevsky   +7 more
doaj   +1 more source