Results 81 to 90 of about 384,012 (260)

Amyloid heart disease mimicking hypertrophic cardiomyopathy* [PDF]

Journal of Internal Medicine, 2005
Abstract.Objective.  To investigate the importance of transthyretin (TTR) gene mutations in explaining the phenotypic expression in patients diagnosed with hypertrophic cardiomyopathy (HCM) in northern Sweden.Background.  Hypertrophic cardiomyopathy is relatively common and often caused by mutations in sarcomeric protein genes.
S, Mörner, U, Hellman, O B, Suhr, E, Kazzam, A, Waldenström   +4 more
openaire   +2 more sources

Ultra High‐Resolution Ultrasound Features of Carpal Tunnel Syndrome in Transthyretin Amyloidosis: A Cross‐Sectional Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Transthyretin amyloidosis (ATTR), including hereditary (hATTR) and wild‐type (wtATTR), often presents initially as carpal tunnel syndrome (CTS), often preceding systemic symptoms by several years. Ultra high‐resolution ultrasound (UHRUS) offers detailed visualization of peripheral nerve morphology, but its application in ATTR‐
Rachana K. Gandhi Mehta, Nicholas Miller, Michael S. Cartwright, Rebecca Traub, Joni Evans   +4 more
wiley   +1 more source

The Underscreening of Cardiac Amyloidosis in Patients With Pacemakers—A Single Centre Retrospective Audit

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Cardiac amyloidosis is commonly associated with cardiac conduction disease. We sought to determine the prevalence of advanced conduction disease requiring a pacemaker in patients with known cardiac amyloidosis to evaluate current screening practices among patients receiving pacemakers.
Peishan Cai, Timothy Scully, Jason Nogic, Kah Peck, Jithin Sajeev   +4 more
wiley   +1 more source

Microfibrillar cardiomyopathy: A rare case

Indian Journal of Pathology and Microbiology, 2011
Microfibrillar cardiomyopathy is a very rare cause of restrictive cardiomyopathy (RCM). The index case was a male patient who presented with shortness of breath and pedal edema. Further clinical investigations favored a clinical diagnosis of RCM.
Narender Kumar, Ruma Ray
doaj   +1 more source

Trajectory of left ventricular geometry and diastolic dysfunction in hereditary transthyretin cardiac amyloidosis

ESC Heart Failure, 2021
Amyloid transthyretin (ATTR) depositions cause left ventricular (LV) hypertrophy, diastolic dysfunction, and heart failure. The time course of changes in LV geometry and diastolic dysfunction has not been fully reported in patients with ATTR ...
Tatsuya Akatsuka, Naoki Fujimoto, Masaki Ishiyama, Shiro Nakamori, Kyoko Imanaka‐Yoshida, Kaoru Dohi   +5 more
doaj   +1 more source

Utilization and Prognosis of Cardiac Device Implantation in AL Versus ATTR Amyloidosis

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Introduction Cardiac amyloidosis can cause congestive heart failure, arrhythmias, and heart blocks, which frequently require cardiac device implantation (CDI). However, the differences between light chain (AL) amyloidosis and transthyretin (ATTR) amyloidosis CDI requirements are unknown. Methods A retrospective analysis was conducted using the
Bilal Hussain, Sanchit Duhan, Khawaja Hassan Akhtar, Amith Reddy Seri, Krittapoom Akrawinthawong, Janardhana Gorthi, Bijeta Keisham, Tarun Dasari   +7 more
wiley   +1 more source

Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes. [PDF]

PLoS ONE, 2015
Light chain (AL) amyloidosis is the most common form of systemic amyloid disease, and cardiomyopathy is a dire consequence, resulting in an extremely poor prognosis.
Helen P McWilliams-Koeppen, James S Foster, Nicole Hackenbrack, Marina Ramirez-Alvarado, Dallas Donohoe, Angela Williams, Sallie Macy, Craig Wooliver, Dale Wortham, Jennifer Morrell-Falvey, Carmen M Foster, Stephen J Kennel, Jonathan S Wall   +12 more
doaj   +1 more source

Hereditary transthyretin amyloidosis: baseline characteristics of patients in the NEURO-TTR trial [PDF]

, 2018
Background: Hereditary transthyretin (ATTRm) amyloidosis is a rare, progressive and fatal disease with a range of clinical manifestations.Objective: This study comprehensively evaluates disease characteristics in a large, diverse cohort of patients with ...
Ackermann, Elizabeth J., Barroso, Fabio A., Benson, Merrill D., Berk, John L., Coelho, Teresa, Dyck, P. James B., Dyck, Peter J., Gertz, Morie A., Heitner, Stephen B., Hughes, Steven G., Jung, Shiangtung W., Kwoh, T. Jesse, Monia, Brett P., Polydefkis, Michael, Tai, Li, Waddington-Cruz, Marcia, Wang, Annabel K.   +16 more
core   +3 more sources

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: a comprehensive review. [PDF]

, 2016
Cardiovascular Magnetic Resonance is increasingly used to differentiate the aetiology of cardiomyopathies. Late Gadolinium Enhancement (LGE) is the reference standard for non-invasive imaging of myocardial scar and focal fibrosis and is valuable in the ...
A Gulati, AM Maceira, C Parsai, CT Sibley, D Carrick, D Carrick, Daniel R. Messroghli, David A. Broadbent, DC Look, DM Sado, DM Sado, DM Sado, DO h-Ici, DR Messroghli, E Dall’Armellina, F aus dem Siepen, FL Ruberg, G Todiere, GC Fonarow, H Xue, H Xue, JA McCrohon, JC Moon, JM Bakker de, JN Dungu, John P. Greenwood, JP Carpenter, JT Clarke, K Chow, KS Patel, M Fontana, M Ugander, MG Friedrich, MS Maron, MY Su, N Kawel, N Kawel-Boehm, NA Ntusi, NA Ntusi, P Gujja, P Kellman, P Kellman, Pankaj Garg, Philip Haaf, PP Swoboda, RB Thompson, RJ Kim, S Dass, S Weingärtner, SK Piechnik, SM Banypersad, Sven Plein, UK Radunski, VM Ferreira, VM Ferreira, VM Ferreira, VO Puntmann, WG Hundley, Y Kobayashi   +58 more
core   +3 more sources