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Mount Sinai Journal of Medicine, 2012 As amyloid neuropathies have benefited from recent major progress, this review is timely and relevant.The main recent articles on amyloid neuropathy cover its description, methods for diagnosis and therapies. Varied clinical presentations are described in transthyretin (TTR)-familial amyloidosis with polyneuropathy (FAP) and light chain amyloid ...
Jessica Robinson-Papp, Susan Shin
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Amyloid Proteins and Peripheral Neuropathy [PDF]
Cells, 2020 Painful peripheral neuropathy affects millions of people worldwide. Peripheral neuropathy develops in patients with various diseases, including rare familial or acquired amyloid polyneuropathies, as well as some common diseases, including type 2 diabetes
Niels Eijkelkamp
exaly +5 more sources
Nerve Biopsy in Peripheral Neuropathies: Not All Water Is under the Bridge
Brain Sciences, 2021 Sural nerve biopsy has long been a valuable diagnostic tool for the study of peripheral neuropathies, although the recent introduction of non-invasive techniques (e.g., neuroimaging techniques, skin biopsy) and advanced genetic and immunological testing ...
Marco Luigetti, Andrea di Paolantonio
exaly +3 more sources
Amyloidosis of the Femoral Neck: An Unusual Cause of Pathologic Fracture
Arthroplasty Today, 2022 The deposition of amyloid within human tissue can be detrimental to the proper functioning of multiple organ systems. While the infiltration of the amyloid protein within the musculoskeletal soft tissues can lead to compressive neuropathies, tendon ...
Christopher A. Worgul, MD +1 more
doaj +1 more source
Diagnosis of amyloid neuropathy [PDF]
Practical Neurology, 2018 Systemic amyloidosis can be hereditary or acquired. The autosomal dominant hereditary transthyretin amyloidosis and the acquired light-chain amyloidosis, the result of a plasma cell dyscrasia, are multisystem disorders with cardiovascular, autonomic and peripheral nerve involvement.
Mahima Kapoor +4 more
openaire +2 more sources
Frontiers in Neurology, 2022 IntroductionHereditary transthyretin amyloidosis (hATTR) can cause multisystem organ disorders including polyneuropathy and cardiomyopathy. Amongst the many known pathologic mutations of the transthyretin (TTR) gene, the Val122Ile (V122I) mutation can be
Jeffrey Z. Shije +3 more
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2021 Background: Hereditary transthyretin-mediated (hATTR) amyloidosis with polyneuropathy is a rare, inherited, multisystem, and often fatal disease caused by a variant in transthyretin (TTR) gene.
Vanessa Cristina Cunha Sequeira +6 more
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Patterns of myelinated nerve fibers loss in transthyretin amyloid polyneuropathy and mimics
Annals of Clinical and Translational Neurology, 2022 Objective The present study was intended to analyze the characteristics of myelinated nerve fibers density (MFD) of transthyretin amyloid polyneuropathy (ATTR‐PN) and other similar neuropathies. Methods A total of 41 patients with ATTR‐PN, 58 patients of
Kang Du +11 more
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Axoval neuropathy as initial manifestation of primary amyloidosis: report of a case submitted to bone marrow transplantation [PDF]
Arquivos de Neuro-Psiquiatria, 2004 Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis).
Orlando G. Povoas Barsottini +6 more
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Frontiers in Human Neuroscience, 2022 Type 2 diabetes mellitus (T2DM) is associated with cognitive impairment in many domains. There are several pieces of evidence that changes in neuronal neuropathies and metabolism have been observed in T2DM.
Hao Lei +8 more
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