Results 11 to 20 of about 4,929 (174)
Diagnosis of amyloid neuropathy [PDF]
Practical Neurology, 2018 Systemic amyloidosis can be hereditary or acquired. The autosomal dominant hereditary transthyretin amyloidosis and the acquired light-chain amyloidosis, the result of a plasma cell dyscrasia, are multisystem disorders with cardiovascular, autonomic and peripheral nerve involvement.
Mahima Kapoor +4 more
openaire +2 more sources
Frontiers in Neurology, 2022 IntroductionHereditary transthyretin amyloidosis (hATTR) can cause multisystem organ disorders including polyneuropathy and cardiomyopathy. Amongst the many known pathologic mutations of the transthyretin (TTR) gene, the Val122Ile (V122I) mutation can be
Jeffrey Z. Shije +3 more
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2021 Background: Hereditary transthyretin-mediated (hATTR) amyloidosis with polyneuropathy is a rare, inherited, multisystem, and often fatal disease caused by a variant in transthyretin (TTR) gene.
Vanessa Cristina Cunha Sequeira +6 more
doaj +1 more source
Patterns of myelinated nerve fibers loss in transthyretin amyloid polyneuropathy and mimics
Annals of Clinical and Translational Neurology, 2022 Objective The present study was intended to analyze the characteristics of myelinated nerve fibers density (MFD) of transthyretin amyloid polyneuropathy (ATTR‐PN) and other similar neuropathies. Methods A total of 41 patients with ATTR‐PN, 58 patients of
Kang Du +11 more
doaj +1 more source
Frontiers in Human Neuroscience, 2022 Type 2 diabetes mellitus (T2DM) is associated with cognitive impairment in many domains. There are several pieces of evidence that changes in neuronal neuropathies and metabolism have been observed in T2DM.
Hao Lei +8 more
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Axoval neuropathy as initial manifestation of primary amyloidosis: report of a case submitted to bone marrow transplantation [PDF]
Arquivos de Neuro-Psiquiatria, 2004 Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis).
Orlando G. Povoas Barsottini +6 more
doaj +1 more source
A Quantitative Assessment of Upper Limb Motor Function Across Disease Stages in Hereditary Transthyretin Amyloidosis. [PDF]
J Peripher Nerv SystABSTRACT Background and Aims Hereditary transthyretin amyloidosis (ATTRv) is a multisystemic disease where early neuropathy signs are challenging to detect conventionally. This study aimed to evaluate hand motor performance in ATTRv using the Hand Test System (HTS) across disease stages and examine correlations with standard measures.
Hamedani M +25 more
europepmc +2 more sources
Clinical Diabetic Peripheral Neuropathy: Can It Be Reversed? Arguments for and Against From a NEUROdiab Debate. [PDF]
J Peripher Nerv SystABSTRACT Diabetic peripheral neuropathy (DPN) is a prevalent and disabling complication of diabetes, yet whether established clinical DPN is reversible remains debated. At the 35th Annual Meeting of NEUROdiab, a formal debate examined arguments ‘for’ and ‘against’ the proposition that clinical DPN can be reversed.
Sloan G +9 more
europepmc +2 more sources
Orphanet Journal of Rare Diseases, 2021 Background Hereditary transthyretin-mediated amyloidosis, also known as ATTRv amyloidosis (v for variant), is a rare, autosomal dominant, fatal disease, in which systemic amyloid progressively impairs multiple organs, leading to disability and death. The
David Adams +5 more
doaj +1 more source
Corneal Confocal Microscopy to Image Small Nerve Fiber Degeneration: Ophthalmology Meets Neurology
Frontiers in Pain Research, 2021 Neuropathic pain has multiple etiologies, but a major feature is small fiber dysfunction or damage. Corneal confocal microscopy (CCM) is a rapid non-invasive ophthalmic imaging technique that can image small nerve fibers in the cornea and has been ...
Ioannis N. Petropoulos +20 more
doaj +1 more source