Results 81 to 90 of about 8,024 (229)

Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay [PDF]

, 2015
BACKGROUND: Currently there are no effective treatments for many neurodegenerative diseases. Reliable biomarkers for identifying and stratifying these diseases will be important in the development of future novel therapies.
Bahtia, K, Bliss, E, Carecchio, M, Fenoglio, C, Fox, NC, Galimberti, D, Hardy, J, Heales, S, Heslegrave, A, Heywood, WE, Magdalinou, NK, Mills, K, Paterson, RW, Reid, E, Scarpini, E, Schott, JM, Sebire, NJ, Sirka, E, Zetterburg, H   +18 more
core   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

Familial Amyloid Polyneuropathy Type IV (FINNISH) with Rapid Clinical Progression in an Iranian Woman: A Case Report

Iranian Journal of Medical Sciences, 2016
Familial amyloid polyneuropathy (FAP) type IV (FINNISH) is a rare clinical entity with challenging neuropathy and cosmetic deficits. Amyloidosis can affect peripheral sensory, motor, or autonomic nerves.
Arash Babaei-Ghazani, Bina Eftekharsadat   +1 more
doaj  

Common Alzheimer's disease risk variant within the CLU gene affects white matter microstructure in young adults [PDF]

, 2011
There is a strong genetic risk for late-onset Alzheimer's disease (AD), but so far few gene variants have been identified that reliably contribute to that risk.
Barysheva, Marina, Braskie, Meredith N., de Zubicaray, Greig I., Jahanshad, Neda, Martin, Nicholas G., McMahon, Katie L., Ringman, John M., Stein, Jason L., Thompson, Paul M., Toga, Arthur W., Wright, Margaret J.   +10 more
core   +2 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Potential role of magnolol: A comprehensive review on its efficacy in managing neurological disorders

Brain Disorders
Magnolol (MG) is a lignan compound isolated from Magnolia officinalis, renowned for its significant neuroprotective properties include the reduction of amyloid-beta toxicity and the inhibition of apoptotic pathways in neuronal cells.
Nasrin Sultana, Mohammed Abu Sayeed, Marajul Islam, S.M. Asadul Karim Azad, Sumaiya Binte Tareq, Miskhat-Ul- Jannat, Farzana Yeasmin   +6 more
doaj   +1 more source

Multiple Myeloma : an update on disease biology and therapy [PDF]

, 2004
Multiple myeloma is a malignancy of immunoglobulin producing plasma cells. Clinical features include bone pain due to lytic bone lesions or pathological fractures, anemia, symptomatic hypercalcemia, renal insufficiency, recurrent infections and ...
Cook, Rachel J., Dingli, David
core  

Alzheimer's Disease: a Review of its Visual System Neuropathology. Optical Coherence Tomography-a Potential Role As a Study Tool in Vivo [PDF]

, 2016
Alzheimer's disease (AD) is a prevalent, long-term progressive degenerative disorder with great social impact. It is currently thought that, in addition to neurodegeneration, vascular changes also play a role in the pathophysiology of the disease. Visual
A Burns, A Kesler, A. Castanheira-Dinis, A. Dias-Santos, AA Sadun, AM Herro, B Katz, BT Hyman, BV Zlokovic, C Murgatroyd, C Paquet, C. Louro, CS Tsai, CY Cheung, CY Cheung, CYL Cheung, D Liu, DP Perl, DR Hinton, E Couser, E Iseki, E Marziani, EG Stopa, EO Oktem, ES Garcia-Martin, F Berisha, FJ Ascaso, FM Chapman, G Coppola, G Katsutoshi, G Leuba, GM McKhann, GM Sawa, HA Bayhan, HV Danesh-Meyer, HW Querfurth, J Keller, J Parvizi, J. Ferreira, J. P. Cunha, JC Blanks, JC Blanks, JM Buren Van, JM Larrosa, JV Drobny, KL Thomson, L Guo, LY Gao, LYL Chang, M Bulut, M Gharbiya, M Koronyo-Hamaoui, M Rizzo, MH Dehabadi, MM Moschos, MP Bambo, N. Moura-Coelho, P Jindahra, P Jindahra, PA Williams, PK Iseri, R Kromer, R Tzekov, R. P. Proença, RA Sperling, RC Petersen, RM Beatty, RO Kuljis, RS Ramrattan, S Frost, S Kirbas, S Mrejen, T Moreno-Ramos, TD Bird, TR Hedges, V Parisi, V Polo, W Choi, WA Fletcher, X-F He, Y Lu, Y Tsai, Y-T Ong   +82 more
core   +1 more source

Real‐World Efficacy of Nab‐Paclitaxel Plus Capecitabine and a PD‐1 Inhibitor in Metastatic or Locally Advanced Esophageal Cancer

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Over half of esophageal cancer (EC) cases occur in China, where paclitaxel and platinum agents have become the preferred chemotherapeutic regimen for EC patients. However, there is a clinical need for a non‐platinum‐based therapeutic option.
Yun Wang, Wei‐Jing Zhang, Yun‐Xin Lu, Shi‐Liang Liu, Zhuo‐Yu Zhang, Si‐Min Zhang, Tian‐Wan Wang, Yu Zhong, Dong‐Sheng Zhang   +8 more
wiley   +1 more source

Integração da resposta simpática da pele no protocolo dos estudos de condução nervosa da Polineuropatia Amiloidótica Familiar e da Polineuropatia Diabética [PDF]

, 2016
Este trabalho foi realizado com o intuito de inserir a Resposta Simpática da Pele no protocolo dos estudos de condução nervosa, nomeadamente no estudo das polineuropatias que aparecem mais frequentemente no Serviço de Neurofisiologia do Centro Hospitalar
Freitas, Mónica Raquel Oliveira Quintas
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