Results 241 to 250 of about 90,332 (308)

Amyloidosis with predominant gastrointestinal symptoms: a challenge for physicians and a burden for patients: a case report. [PDF]

J Med Case Rep
Dinavari MF, Khodadadi K, Eftekhar-Sadat AT.   +2 more
europepmc   +1 more source

Too close for comfort: Self‐crowding transforms protein structure and stability beyond volume exclusion

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Proteins operate in crowded physiological environments, yet their conformational and oligomeric states are largely inferred from experiments performed under dilute buffer conditions. Here, we show that for lysozyme (LYS) and bovine serum albumin (BSA), self‐crowding at physiologically relevant concentrations alters protein structure and ...
Gil I. Olgenblum, Yehonatan N. Levy, Daniel Harries   +2 more
wiley   +1 more source

Case Report: Systemic amyloidosis unmasked by progressive hepatomegaly after splenectomy for non-traumatic spleen rupture in a patient with chronic liver disease. [PDF]

Front Med (Lausanne)
Sheng LP, Zhang YY, Zhang M, Lin BZ, Ma RF, Han LN, Liu H, Hou FQ, Wang GQ.   +8 more
europepmc   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Evaluation of the Current ATTR‐CM Treatment Landscape via a Mathematical Model of TTR Dissociation and Amyloid Formation

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Transthyretin amyloid cardiomyopathy (ATTR‐CM) is a progressive, often fatal disease arising from the dissociation of circulating transthyretin (TTR) tetramers into monomers that misfold and form amyloid fibrils that deposit in the myocardium and other tissues. Approved treatment paradigms involve tetramer stabilization with small molecules or
Stevan Methven Jeknić, Travis A. Ahn‐Horst, Alan X. Ji, Jin Hyun Ju, Morgan Paull, Sun‐Gou Ji, Uma Sinha   +6 more
wiley   +1 more source

Diagnostic Yield of Abdominal Wall Fat Pad Biopsy for Systemic Amyloidosis in a Low-Prevalence Referral Cohort. [PDF]

Dermatol Pract Concept
Teixeira J, Teixeira D, Coelho A, Cardoso JC.   +3 more
europepmc   +1 more source

Crescentic Glomerulonephritis in a Patient With AL Amyloidosis: A Case Report. [PDF]

Kidney Med
Charkviani M, Cardoso C, Muchtar E, Nasr SH, Leung N.   +4 more
europepmc   +1 more source

Urological manifestations in familial Mediterranean fever excluding renal amyloidosis: a systematic review. [PDF]

Rheumatology (Oxford)
Ozcan AK, Karaoglan B, Gundogdu B, Sahin C, Simsekoglu MF, Ugurlu S.   +5 more
europepmc   +1 more source

Incidental discovery of acquired factor X deficiency in a patient with multiple myeloma. [PDF]

Leuk Res Rep
Sbibih Y, Bensalah M, Saddari A, Slaoui M, Trougouty N, Berhili A, Seddik R.   +6 more
europepmc   +1 more source

Rheumatological Manifestations of Systemic Amyloidosis: A Retrospective Single-Centre Study From a Tertiary Care Hospital in India. [PDF]

Cureus
Gopal M, George N A, Kamath N, Thomas KN, Goel R, Mathew J.   +5 more
europepmc   +1 more source