Serum Amyloid A Protein–Associated Kidney Disease: Presentation, Diagnosis, and Management [PDF]
Kidney Medicine, 2022 Serum amyloid A protein (AA) amyloidosis, also known as secondary amyloidosis, is a known consequence of chronic inflammation and results from several conditions including inflammatory arthritis, periodic fever syndromes, and chronic infection.
Jordan Thorne +5 more
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RETRACTED: Serum amyloid A protein in the course of infectious mononucleosis
Therapeutic Advances in Infectious Disease, 2019 Serum amyloid A (SAA) protein is a major acute phase protein. Increased concentrations have been reported in many inflammatory diseases. In bacterial infections, high levels correlate with those of C-reactive protein (CRP). In viral infections, where CRP changes are weaker, SAA is of value for establishing early diagnosis, monitoring the severity, and ...
Iliyan Todorov +3 more
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BMC Gastroenterology, 2020 Background Many studies have revealed that mucosal healing improves the long-term prognosis of ulcerative colitis. Frequent colonoscopy is difficult because of its invasiveness and cost.
Masaki Wakai +10 more
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Aggregation of Mouse Serum Amyloid A Protein Was Promoted by Amyloid-Enhancing Factors with the More Genetically Homologous Serum Amyloid A [PDF]
International Journal of Molecular Sciences, 2021 Amyloid A (AA) amyloidosis is a condition in which amyloid fibrils characterized by a linear morphology and a cross-β structure accumulate and are deposited extracellularly in organs, resulting in chronic inflammatory diseases and infections. The incidence of AA amyloidosis is high in humans and several animal species.
Xuguang Lin +3 more
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C-reactive protein and serum amyloid A protein as complementary biomarkers in differentiating viral and bacterial community-acquired pneumonia in children [PDF]
BMC PediatricsObjective Distinguishing between viral and bacterial community-acquired pneumonia (CAP) in children is crucial for guiding targeted management and antibiotic use.
Juan Cheng +8 more
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Serum Amyloid A Protein Concentration in Blood is Influenced by Genetic Differences in the Cheetah (Acinonyx jubatus). [PDF]
J Hered, 2016 Systemic amyloid A (AA) amyloidosis is a major cause of morbidity and mortality among captive cheetahs. The self-aggregating AA protein responsible for this disease is a byproduct of serum amyloid A (SAA) protein degradation. Transcriptional induction of
Franklin AD +4 more
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The diagnostic performance of point-of-care tests for serum amyloid A and C-reactive protein in lame sows [PDF]
Acta Veterinaria ScandinavicaBackground For acute phase proteins to be implemented in routine diagnostics for pig herds, a fast, reliable, and portable point-of-care test is required.
Nadia Jakobsen +3 more
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Transplantation, 1983 Acute human renal allograft rejection induces a dramatic elevation of serum amyloid A protein (SAA). To evaluate the clinical significance of this finding we monitored 31 consecutive recipients of cadaveric renal allografts by daily SAA measurements. SAA increased significantly during 37/38 rejection episodes.
C P, Maury +3 more
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Cellular mechanism of fibril formation from serum amyloid A1 protein [PDF]
EMBO Reports, 2017 Paul Walther +2 more
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Revisiting misfolding propensity of serum amyloid A1: Special focus on the signal peptide region
Biochemistry and Biophysics Reports, 2022 AA amyloidosis is the result of overproduction and aberrant processing of acute-phase serum amyloid A1 (SAA1) by hepatocytes. Proteolytic cleavage of SAA1 is believed to play a central role in AA amyloid formation.
Morgan S. Haines +3 more
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