Results 1 to 10 of about 35,609 (207)
Neoplasia, 2007 OBJECTIVE: This study was conducted to evaluate the prognostic significance of haptoglobin levels in the overall survival of patients presenting with various stages of epithelial ovarian cancer.
Huoming Zhang +2 more
exaly +3 more sources
Haptoglobin-Conjugated Gold Nanoclusters as a Nanoantibiotic to Combat Bacteremia
Nanomaterials, 2022 Gold nanoclusters have revealed great potential as nanoantibiotics due to their superior chemical and physical characteristics. In this study, a peptide with 83 amino acids derived from haptoglobin was utilized as a surface ligand to synthesize gold ...
Hsiu-Yi Chu +6 more
doaj +1 more source
Role of haptoglobin in polycystic ovary syndrome (PCOS), obesity and disorders of glucose tolerance in premenopausal women. [PDF]
PLoS ONE, 2009 BackgroundHp(2) alleles of the haptoglobin alpha-chain polymorphism reduce the anti-oxidant properties and increase the pro-inflammatory actions of this acute-phase protein in a gene-dosage fashion. We hypothesized that the haptoglobin polymorphism might
Francisco Alvarez-Blasco +5 more
doaj +1 more source
Frontiers in Physiology, 2022 Background: In sickle cell disease (SCD), reduced bioavailability of endothelial NO and cGMP results in reduced expression of phosphodiesterase type 5 (PDE5), thus impairing the penile erection control mechanism and resulting in prolonged penile erection
Pamela da Silva Pereira +8 more
doaj +1 more source
Scientific Reports, 2021 Recent evidence supports involvement of the acute phase protein haptoglobin in numerous events during mammalian reproduction. The present study represents an in-depth investigation of haptoglobin expression and secretion in the porcine oviduct and uterus,
Francisco A. García-Vázquez +10 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2021 Aim. To study the relationship between the level of haptoglobin and the main indicators of microcirculation (MC) in patients with different phenotypes of chronic heart failure (CHF).Materials and methods.
V. I. Podzolkov +4 more
doaj +1 more source
Impact of Haptoglobin Gene Polymorphism on Phenotypic Variability in β-thalassemia Patients: Relation to Iron Overload and Oxidative Stress [PDF]
Afro-Egyptian Journal of Infectious and Endemic Diseases, 2023 Background and study aim: Thalassemia syndromes are genetic disorders in globin chain production. There is excessive synthesis of reactive oxygen species in thalassemia which leads to oxidative stress.
Ola Balbaa +3 more
doaj +1 more source
Haptoglobin release by human adipose tissue in primary culture
Journal of Lipid Research, 2004 Haptoglobin is a putative adiposity marker because its concentration in blood is increased in obese humans. The present studies examined haptoglobin release by explants of adipose tissue in primary culture.
John N. Fain +2 more
doaj +1 more source
Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction. [PDF]
PLoS ONE, 2018 During hemolysis, hemoglobin and heme released from red blood cells promote oxidative stress, inflammation and thrombosis. Plasma haptoglobin and hemopexin scavenge free hemoglobin and heme, respectively, but can be depleted in hemolytic states ...
John D Belcher +12 more
doaj +1 more source
Journal of Veterinary Internal Medicine, 2023 Background Serum 25‐hydroxyvitamin (OH)D, C‐reactive protein (CRP), and haptoglobin are useful biomarkers in various infectious diseases and inflammatory disorders in dogs, but their utility in histoplasmosis is unknown.
Betsy Hernandez +11 more
doaj +1 more source