Results 1 to 10 of about 30,258 (158)

Early Decline in Serum Haptoglobin During Impella CP Support Compared With Intra‐Aortic Balloon Pump in Cardiogenic Shock: A Single‐Center Observational Study [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Hemolysis is a recognized complication of mechanical circulatory support and may contribute to acute kidney injury in patients with cardiogenic shock. Early hemolysis during Impella support, particularly compared with intra‐aortic balloon pump
Shoji Kawakami, Daisuke Kawakami, Masato Takei, Yoshihiro Ota, Yosuke Matsumoto, Shihomi Nawata, Eigo Nawata, Hidenobu Koga, Jun‐Ichiro Nishi   +8 more
doaj   +2 more sources

Diagnostic accuracy of intraoperative haptoglobin point-of-care testing in ovarian tumor fluid versus frozen section for epithelial ovarian cancer [PDF]

BMC Research Notes
Objective Ovarian cancer is the third most common gynaecological cancer and has the high mortality rates and requires accurate intraoperative. Haptoglobin is an acute-phase protein locally elevated in cancer cells, may serve as a novel diagnostic marker.
Benyamin Rakhmatsyah Titaley, Siti Salima, Andi Kurniadi, Dodi Suardi, Ali Budi Harsono, Gatot Nyarumenteng Adhipurnawan Winarno, Patiyus Agustiansyah, Aisyah Shofiatun Nisa   +7 more
doaj   +2 more sources

Haptoglobin as a Biomarker [PDF]

Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry, 2021
Haptoglobin (Hp) is a blood plasma glycoprotein that binds free hemoglobin (Hb) and plays a critical role in tissue protection and the prevention of oxidative damage. In addition, it has a number of regulatory functions. Haptoglobin is an acute phase protein, its concentration in plasma changes in pathology, and the test for its concentration is ...
Naryzny, S. N., Legina, O. K.
openaire   +4 more sources

Role of haptoglobin in polycystic ovary syndrome (PCOS), obesity and disorders of glucose tolerance in premenopausal women. [PDF]

PLoS ONE, 2009
BackgroundHp(2) alleles of the haptoglobin alpha-chain polymorphism reduce the anti-oxidant properties and increase the pro-inflammatory actions of this acute-phase protein in a gene-dosage fashion. We hypothesized that the haptoglobin polymorphism might
Francisco Alvarez-Blasco, Ma Angeles Martínez-García, Manuel Luque-Ramírez, Naiara Parraza, José L San Millán, Héctor F Escobar-Morreale   +5 more
doaj   +1 more source

Haptoglobin-Conjugated Gold Nanoclusters as a Nanoantibiotic to Combat Bacteremia

Nanomaterials, 2022
Gold nanoclusters have revealed great potential as nanoantibiotics due to their superior chemical and physical characteristics. In this study, a peptide with 83 amino acids derived from haptoglobin was utilized as a surface ligand to synthesize gold ...
Hsiu-Yi Chu, Lung-Ching Chen, Tsung-Rong Kuo, Chun-Che Shih, Sibidou Yougbaré, Yu-Han Chen, Tsai-Mu Cheng   +6 more
doaj   +1 more source

Haptoglobin treatment contributes to regulating nitric oxide signal and reduces oxidative stress in the penis: A preventive treatment for priapism in sickle cell disease

Frontiers in Physiology, 2022
Background: In sickle cell disease (SCD), reduced bioavailability of endothelial NO and cGMP results in reduced expression of phosphodiesterase type 5 (PDE5), thus impairing the penile erection control mechanism and resulting in prolonged penile erection
Pamela da Silva Pereira, Dalila Andrade Pereira, Fabiano Beraldi Calmasini, Leonardo O. Reis, Nathan Brinkman, Arthur L. Burnett, Fernando Ferreira Costa, Fábio Henrique Silva, Fábio Henrique Silva   +8 more
doaj   +1 more source

Evidence of haptoglobin in the porcine female genital tract during oestrous cycle and its effect on in vitro embryo production

Scientific Reports, 2021
Recent evidence supports involvement of the acute phase protein haptoglobin in numerous events during mammalian reproduction. The present study represents an in-depth investigation of haptoglobin expression and secretion in the porcine oviduct and uterus,
Francisco A. García-Vázquez, Carla Moros-Nicolás, Rebeca López-Úbeda, Ernesto Rodríguez-Tobón, Ascensión Guillén-Martínez, Jason W. Ross, Chiara Luongo, Carmen Matás, Iván Hernández-Caravaca, Manuel Avilés, Mª José Izquierdo-Rico   +10 more
doaj   +1 more source

Endothelial Microvascular Dysfunction and Its Relationship with Haptoglobin Levels in Patients with Different Phenotypes of Chronic Heart Failure

Рациональная фармакотерапия в кардиологии, 2021
Aim. To study the relationship between the level of haptoglobin and the main indicators of microcirculation (MC) in patients with different phenotypes of chronic heart failure (CHF).Materials and methods.
V. I. Podzolkov, N. A. Dragomiretskaya, I. G. Beliaev, Ju. S. Kucherova, A. V. Kazadaeva   +4 more
doaj   +1 more source

Impact of Haptoglobin Gene Polymorphism on Phenotypic Variability in β-thalassemia Patients: Relation to Iron Overload and Oxidative Stress [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases, 2023
Background and study aim: Thalassemia syndromes are genetic disorders in globin chain production. There is excessive synthesis of reactive oxygen species in thalassemia which leads to oxidative stress.
Ola Balbaa, Maher Kamel, Khaled Salem, Nadia Sadek   +3 more
doaj   +1 more source

Haptoglobin release by human adipose tissue in primary culture

Journal of Lipid Research, 2004
Haptoglobin is a putative adiposity marker because its concentration in blood is increased in obese humans. The present studies examined haptoglobin release by explants of adipose tissue in primary culture.
John N. Fain, Suleiman W. Bahouth, Atul K. Madan   +2 more
doaj   +1 more source