Results 31 to 40 of about 41,191 (221)

Clinical Usefulness of Haptoglobin Levels to Evaluate Hemolysis in Recently Transfused Patients

Advances in Hematology, 2011
Introduction. Haptoglobin binds the globin portion of free hemoglobin. Serum haptoglobin measurement is used as a laboratory marker for the diagnosis of hemolytic anemia.
Shilpi Gupta, Kathleen Ahern, Fadi Nakhl, Frank Forte   +3 more
doaj   +1 more source

A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.

PLoS ONE, 2012
Haptoglobin is an acute phase inflammatory marker. Its main function is to bind hemoglobin released from erythrocytes to aid its elimination, and thereby haptoglobin prevents the generation of reactive oxygen species in the blood. Haptoglobin levels have
Philippe Froguel, Ndeye Coumba Ndiaye, Amélie Bonnefond, Nabila Bouatia-Naji, Aurélie Dechaume, Gérard Siest, Bernard Herbeth, Mario Falchi, Leonardo Bottolo, Rosa-Maria Guéant-Rodriguez, Cécile Lecoeur, Michel R Langlois, Yann Labrune, Aimo Ruokonen, Said El Shamieh, Maria G Stathopoulou, Anita Morandi, Claudio Maffeis, David Meyre, Joris R Delanghe, Peter Jacobson, Lars Sjöström, Lena M S Carlsson, Andrew Walley, Paul Elliott, Marjo-Riita Jarvelin, George V Dedoussis, Sophie Visvikis-Siest   +27 more
doaj   +1 more source

Antiphospholipid antibodies in healthy Serbian middle-aged subjects: Preliminary data [PDF]

Journal of Medical Biochemistry, 2022
Background: The investigation of the prevalence of the IgG and the IgM isotypes of anticardiolipin (aCL) and antib2glycoprotein I (ab2gpI) Abs in healthy Serbian middleaged subjects was the main goal of our study.
Bećarević Mirjana B., Jovičić Snežana, Ignjatović Svetlana D., Mirković Duško   +3 more
doaj   +1 more source

Modern markers of inflammatory process in surgical practice

Амбулаторная хирургия, 2022
Introduction. Currently, one of the important problems in surgery is the search for new markers of the inflammatory process to determine the prognosis of the disease, substantiate the need for surgical intervention and to assess the effectiveness of ...
A. M. Morozov, A. N. Sergeev, S. V. Zhukov, N. S. Novikova, M. A. Belyak   +4 more
doaj   +1 more source

Contribution of O-GlcNAc modification of NF-κB p65 in the attenuation of diabetes-induced haptoglobin expression in rat liver [PDF]

Archives of Biological Sciences, 2020
Haptoglobin (Hp) is a hemoglobin-binding protein that prevents free hemoglobin-induced tissue oxidative damage. In streptozotocin-induced diabetic rats, the initial elevation of Hp expression in the serum and liver tends to decrease with diabetes ...
Martinović Vesna I., Arambašić-Jovanović Jelena D., Bogojević Desanka B., Ivanović Anđelija S., Otašević Vesna M., Stančić Ana T., Grigorov Ilijana I.   +6 more
doaj   +1 more source

Effects of dietary butyrate supplementation and oral nonsteroidal anti-inflammatory drug administration on serum inflammatory markers and productivity of dairy cows during the calving transition

Journal of Dairy Science, 2022
: Dairy cattle experience inflammation during the calving transition period, and butyrate and nonsteroidal anti-inflammatory drugs (NSAID) are expected to reduce the inflammation.
L.E. Engelking, D.J. Ambrose, M. Oba
doaj   +1 more source

The role of cell-free hemoglobin and haptoglobin in acute kidney injury in critically ill adults with ARDS and therapy with VV ECMO

Critical Care, 2022
Background Increased plasma concentrations of circulating cell-free hemoglobin (CFH) are supposed to contribute to the multifactorial etiology of acute kidney injury (AKI) in critically ill patients while the CFH-scavenger haptoglobin might play a ...
Jan A. Graw, Philip Hildebrandt, Alexander Krannich, Felix Balzer, Claudia Spies, Roland C. Francis, Wolfgang M. Kuebler, Steffen Weber-Carstens, Mario Menk, Oliver Hunsicker   +9 more
doaj   +1 more source

Circulating Haptoglobin Is an Independent Prognostic Factor in the Sera of Patients with Epithelial Ovarian Cancer

Neoplasia: An International Journal for Oncology Research, 2007
OBJECTIVE: This study was conducted to evaluate the prognostic significance of haptoglobin levels in the overall survival of patients presenting with various stages of epithelial ovarian cancer.
Changqing Zhao, Loganath Annamalai, Changfa Guo, Narasimhan Kothandaraman, Stephen Chee Liang Koh, Huoming Zhang, Arijit Biswas, Mahesh Choolani   +7 more
doaj   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Quantification of Intact O-Glycopeptides on Haptoglobin in Sera of Patients With Hepatocellular Carcinoma and Liver Cirrhosis

Frontiers in Chemistry, 2021
Haptoglobin (Hp) is one of the acute-phase response proteins secreted by the liver, and its aberrant N-glycosylation was previously reported in hepatocellular carcinoma (HCC). Limited studies on Hp O-glycosylation have been previously reported.
Hong Shu, Hong Shu, Lei Zhang, Yiwei Chen, Yijie Guo, Limin Li, Fanghua Chen, Zhao Cao, Guoquan Yan, Chunlai Lu, Chao Liu, Shu Zhang   +11 more
doaj   +1 more source