Results 51 to 60 of about 41,191 (221)

Venous blood lactate concentration as a predictor of intestinal viability in horses with acquired indirect inguinal hernia

Equine Veterinary Journal, EarlyView.
Abstract Background Acquired indirect inguinal hernia represents a life‐threatening emergency. Therapeutic decision‐making largely depends on intestinal viability, for which specific predictive parameters (such as venous lactate) have not been evaluated.
Raquel Rivero‐García, Cristina Andreu‐Vázquez, Beatriz Fuentes‐Romero, Pablo Fernández‐Hernández, María Luisa Rodríguez‐Pozo, Ignacio Aguilar Sebastián, Salvador Termes Soto, Mercedes Martínez Gallardo, Manuel Iglesias‐García   +8 more
wiley   +1 more source

Human Protein Biomarkers Outperform Bacterial Proteins in Colorectal Cancer Detection

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) generally develops from precancerous adenomatous lesions, including advanced adenomas (AA), through a sequence of carcinogenic molecular alterations. The composition of the gut microbiota and the fecal proteome is known to differ between individuals with AA and CRC compared to controls, providing opportunities for ...
Roza C. M. Opperman, Sofie Bosch, Alex A. Henneman, Thang V. Pham, Sander R. Piersma, Tim G. J. de Meij, Meike de Wit, Beatriz Carvalho, Remond J. A. Fijneman, Gerrit A. Meijer, Evelien Dekker, Connie R. Jimenez, Nanne K. H. de Boer   +12 more
wiley   +1 more source

Haptoglobin genotype is a risk factor for coronary artery disease in prediabetes: A case-control study

American Journal of Preventive Cardiology
Objective: Coronary artery disease (CAD) prediction remains inconsistent with many unappreciated risk factors. Haptoglobin genotype determines the haptoglobin protein's effectiveness to bind free hemoglobin and prevent oxidative stress, a contributor to ...
Emily Kate Mewborn, Elizabeth Ann Tolley, David Bruce Wright, Amy Lynn Doneen, Margaret Harvey, Ansley Grimes Stanfill   +5 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Haptoglobin gene polymorphism influences the effect of malaria infection on host haptoglobin plasma level but not susceptibility to the disease [PDF]

, 2016
A cohort of 344 children aged less than five years were followed for one year to establish the relationship between haptoglobin genotype, haptoglobin plasma level and malaria infection and susceptibility.
Alfred, Benigni, Gwakisa, Paul
core   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

Small, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale, Andrea Mussini, Òscar Gulías, Montserrat Agut, Melissa Berni, Stefano Pongolini, Stefano Bruno, Alessandro Casnati, Santi Nonell, Cristiano Viappiani, Stefania Abbruzzetti   +10 more
wiley   +1 more source

HIgher concentration of haptoglogin indicates transient inflammation and negative energy balance in transition cows [PDF]

Journal of Veterinary and Animal Sciences, 2020
Haptoglobin is an acute phase protein that is of diagnostic significance in dairy cattle. In the present study, haptoglobin level was assessed during the periparturient period in 15 clinically healthy pregnant cows.
S.V. Vasudhar Bhat , J.P. Anisha , M. Shynu, K.K. Jayavardhanan, V. Ramnath   +4 more
doaj  

Evaluation of plasma and milk haptoglobin concentrations in the diagnosis and treatment follow-up of subclinical mastitis in dairy cows [PDF]

Acta Veterinaria, 2012
The purpose of this study was to examine whether plasma and milk haptoglobin (Hp) concentrations could be an alternative method for the diagnosis and treatment follow-up of subclinical mastitis (SM) in dairy cows.
Gultiken Nilgun, Serhat Ay S., Gul Fatma Yarim, Elvan Anadol, Findik M.   +4 more
doaj   +1 more source