Results 51 to 60 of about 38,975 (198)

Haptoglobin genotype is a risk factor for coronary artery disease in prediabetes: A case-control study

American Journal of Preventive Cardiology
Objective: Coronary artery disease (CAD) prediction remains inconsistent with many unappreciated risk factors. Haptoglobin genotype determines the haptoglobin protein's effectiveness to bind free hemoglobin and prevent oxidative stress, a contributor to ...
Emily Kate Mewborn, Elizabeth Ann Tolley, David Bruce Wright, Amy Lynn Doneen, Margaret Harvey, Ansley Grimes Stanfill   +5 more
doaj   +1 more source

Ceftriaxone‐associated immune haemolytic anaemia: A patient‐level systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Ceftriaxone can cause acute haemolysis. Its clinical presentation, risk factors, and outcomes remain incompletely characterized. We conducted a systematic review of published cases with patient‐level data, following international guidelines and with registration in PROSPERO (CRD420261338709). Reports were identified through three bibliographic
Sonja Miotti, Giada Wyttenbach, Mario G. Bianchetti, Camilla Lavagno, Pietro Camozzi, Gregorio P. Milani, Renato Gualtieri, Sebastiano A. G. Lava, Pietro B. Faré, Simone Janett   +9 more
wiley   +1 more source

Small scale purification and biophysical characterization of haptoglobin derived from human Cohn fraction IV

Biotechnology Progress, EarlyView.
Abstract Haptoglobin (Hp) is a polymorphic acute phase α‐2 glycoprotein found in plasma that plays a critical role in binding, neutralizing, and removing cell‐free hemoglobin (Hb) from the circulation. Under clinical conditions characterized by high levels of hemolysis, such as in patients with sickle cell disease (SCD), large quantities of cell‐free ...
Shuwei Lu, Mohd Asim Khan, Pedro Cabrales, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +5 more
wiley   +1 more source

Venous blood lactate concentration as a predictor of intestinal viability in horses with acquired indirect inguinal hernia

Equine Veterinary Journal, EarlyView.
Abstract Background Acquired indirect inguinal hernia represents a life‐threatening emergency. Therapeutic decision‐making largely depends on intestinal viability, for which specific predictive parameters (such as venous lactate) have not been evaluated.
Raquel Rivero‐García, Cristina Andreu‐Vázquez, Beatriz Fuentes‐Romero, Pablo Fernández‐Hernández, María Luisa Rodríguez‐Pozo, Ignacio Aguilar Sebastián, Salvador Termes Soto, Mercedes Martínez Gallardo, Manuel Iglesias‐García   +8 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

HIgher concentration of haptoglogin indicates transient inflammation and negative energy balance in transition cows [PDF]

Journal of Veterinary and Animal Sciences, 2020
Haptoglobin is an acute phase protein that is of diagnostic significance in dairy cattle. In the present study, haptoglobin level was assessed during the periparturient period in 15 clinically healthy pregnant cows.
S.V. Vasudhar Bhat , J.P. Anisha , M. Shynu, K.K. Jayavardhanan, V. Ramnath   +4 more
doaj  

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Early Decline in Serum Haptoglobin During Impella CP Support Compared With Intra‐Aortic Balloon Pump in Cardiogenic Shock: A Single‐Center Observational Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Hemolysis is a recognized complication of mechanical circulatory support and may contribute to acute kidney injury in patients with cardiogenic shock. Early hemolysis during Impella support, particularly compared with intra‐aortic balloon pump
Shoji Kawakami, Daisuke Kawakami, Masato Takei, Yoshihiro Ota, Yosuke Matsumoto, Shihomi Nawata, Eigo Nawata, Hidenobu Koga, Jun‐Ichiro Nishi   +8 more
doaj   +1 more source

Evaluation of plasma and milk haptoglobin concentrations in the diagnosis and treatment follow-up of subclinical mastitis in dairy cows [PDF]

Acta Veterinaria, 2012
The purpose of this study was to examine whether plasma and milk haptoglobin (Hp) concentrations could be an alternative method for the diagnosis and treatment follow-up of subclinical mastitis (SM) in dairy cows.
Gultiken Nilgun, Serhat Ay S., Gul Fatma Yarim, Elvan Anadol, Findik M.   +4 more
doaj   +1 more source

Basophilic Stippling Unmasks Pyrimidine 5′‐Nucleotidase Deficiency in a G6PD‐Deficient Patient

American Journal of Hematology, EarlyView.
Victor Bobée, Stéphane Moutereau, Maïssa Souissi, Pierre Lebreton, Loïc Garcon   +4 more
wiley   +1 more source