Results 271 to 280 of about 148,376 (307)
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Current Opinion in Rheumatology, 1996
Developments concerning amyloidosis associated with rheumatic diseases or often causing musculoskeletal symptoms are reviewed. The pathogenesis, clinical manifestations, diagnosis, and therapy of amyloid A, amyloid light-chain, and amyloid beta 2-microglobulin amyloidosis are discussed from the standpoint of a clinical rheumatologist.
C, Friman, T, Pettersson
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Developments concerning amyloidosis associated with rheumatic diseases or often causing musculoskeletal symptoms are reviewed. The pathogenesis, clinical manifestations, diagnosis, and therapy of amyloid A, amyloid light-chain, and amyloid beta 2-microglobulin amyloidosis are discussed from the standpoint of a clinical rheumatologist.
C, Friman, T, Pettersson
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Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy.
New England Journal of MedicineBACKGROUND Transthyretin amyloidosis with cardiomyopathy (ATTR-CM) is a progressive, fatal disease. Vutrisiran, a subcutaneously administered RNA interference therapeutic agent, inhibits the production of hepatic transthyretin.
M. Fontana +36 more
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Prevalence and clinical outcomes of transthyretin amyloidosis: a systematic review and meta‐analysis
European Journal of Heart Failure, 2022Systematic evidence on the prevalence and clinical outcome of transthyretin amyloidosis (ATTR) is missing. We explored: (i) the prevalence of cardiac amyloidosis in various patient subgroups, (ii) survival estimates for ATTR subtypes, and (iii) the ...
A. Antonopoulos +9 more
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Cardiac Amyloidosis Due to Transthyretin Protein: A Review.
Journal of the American Medical Association (JAMA)Importance Systemic amyloidosis from transthyretin (ATTR) protein is the most common type of amyloidosis that causes cardiomyopathy. Observations Transthyretin (TTR) protein transports thyroxine (thyroid hormone) and retinol (vitamin A) and is ...
F. Ruberg, Mathew S. Maurer
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Systemic Amyloidosis Recognition, Prognosis, and Therapy: A Systematic Review.
Journal of the American Medical Association (JAMA), 2020Importance Many patients with systemic amyloidosis are underdiagnosed. Overall, 25% of patients with immunoglobulin light chain (AL) amyloidosis die within 6 months of diagnosis and 25% of patients with amyloid transthyretin (ATTR) amyloidosis die within
M. Gertz, A. Dispenzieri
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Journal of the American Podiatric Medical Association, 1990
The authors present a review of amyloidosis and its classification and clinical presentations. They also discuss its diagnosis and treatment, and present a case of amyloid deposition in the plantar weightbearing aspects of the feet, which exemplifies the classic clinical findings.
P K, Geistler, K G, Canter, N A, Staley
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The authors present a review of amyloidosis and its classification and clinical presentations. They also discuss its diagnosis and treatment, and present a case of amyloid deposition in the plantar weightbearing aspects of the feet, which exemplifies the classic clinical findings.
P K, Geistler, K G, Canter, N A, Staley
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Histopathology, 1994
Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils which are dérived from different proteins in different forms of the disease. Asymptomatic amyloid deposition in a variety of tissues is a universal accompaniment of ageing, and clinical amyloidosis is not rare.
S Y, Tan, M B, Pepys
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Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils which are dérived from different proteins in different forms of the disease. Asymptomatic amyloid deposition in a variety of tissues is a universal accompaniment of ageing, and clinical amyloidosis is not rare.
S Y, Tan, M B, Pepys
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Current Treatment Options in Oncology, 2006
Amyloidosis is a disease in which abnormal proteins form fibrillar tissue deposits that can compromise key viscera and lead to early death. In order to treat amyloidosis, the type of abnormal protein must be identified. The most common type is monoclonal immunoglobulin light chain or AL amyloidosis; the other important type is hereditary, caused by ...
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Amyloidosis is a disease in which abnormal proteins form fibrillar tissue deposits that can compromise key viscera and lead to early death. In order to treat amyloidosis, the type of abnormal protein must be identified. The most common type is monoclonal immunoglobulin light chain or AL amyloidosis; the other important type is hereditary, caused by ...
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Otorinolaringologia, 2020
Laryngeal amyloidosis is a rare and idiopathic disease that represents about 1% of all benign laryngeal lesions. It is characterized by the extracellular deposition of an abnormal amount of non-soluble fibrillar proteins in larynx. This disease presents unspecific symptoms and laringoscopic findings that make difficult to diagnose it.
Verro B., Ferrara S., Gargano R.
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Laryngeal amyloidosis is a rare and idiopathic disease that represents about 1% of all benign laryngeal lesions. It is characterized by the extracellular deposition of an abnormal amount of non-soluble fibrillar proteins in larynx. This disease presents unspecific symptoms and laringoscopic findings that make difficult to diagnose it.
Verro B., Ferrara S., Gargano R.
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Orvosi Hetilap, 2010
Az amyloidosis különböző eredetű fibrilláris jellegű anyag extracelluláris felhalmozódása. Különböző szervekben lerakódva azok működését károsítja. A funkciókárosodásból adódnak a klinikai tünetek, az agyon kívül minden szerv érintett lehet, leggyakrabban a vese, a máj, a lép, a gastrointestinalis rendszer, az endokrin szervek, a bőr, a szív, a tüdő és
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Az amyloidosis különböző eredetű fibrilláris jellegű anyag extracelluláris felhalmozódása. Különböző szervekben lerakódva azok működését károsítja. A funkciókárosodásból adódnak a klinikai tünetek, az agyon kívül minden szerv érintett lehet, leggyakrabban a vese, a máj, a lép, a gastrointestinalis rendszer, az endokrin szervek, a bőr, a szív, a tüdő és
openaire +3 more sources