Results 281 to 290 of about 200,281 (336)

Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction.

open access: yesEuropean Heart Journal, 2015
E. Gonzalez-Lopez   +10 more
semanticscholar   +1 more source

Impact of preanalytical delay on the performance of plasma Aβ42, Aβ42/40, p‐tau217, and p‐tau217/Aβ42 in detecting brain amyloidosis in the ALZAN cohort

open access: yesAlzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract BACKGROUND Alzheimer disease (AD), the leading cause of dementia, has increased interest in the development of blood‐based biomarkers for early diagnosis and monitoring. The plasma amyloid beta (Aβ)42/Aβ40 ratio and phosphorylated tau (p‐tau) isoforms closely align with cerebrospinal fluid and positron emission tomography markers.
Constance Delaby   +13 more
wiley   +1 more source

Frequency of Microvascular Pathology and Hippocampal Atrophy on Magnetic Resonance Imaging in a Community Study of Alzheimer's Disease with Blood‐Based Biomarkers

open access: yesAnnals of Neurology, Volume 98, Issue 5, Page 1027-1043, November 2025.
Objective Blood‐based biomarkers for Alzheimer's disease (AD), representing antemortem indicators of AD pathophysiology, have greatly improved the accuracy of diagnosis. However, these biomarkers may not capture a frequent coincident pathology, such as cerebrovascular disease.
Tamil Iniyan Gunasekaran   +12 more
wiley   +1 more source

Cardiac Amyloidosis: Tribulations and New Frontiers. [PDF]

open access: yesJ Pers Med
Nguyen DM, Ramazani N, Sodhi G, Tak T.
europepmc   +1 more source

Prognostic Implications of Thrombocytopenia in Chinese Patients With Newly Diagnosed Multiple Myeloma

open access: yesCancer Medicine, Volume 14, Issue 21, November 2025.
ABSTRACT Background Thrombocytopenia is less common but shows high risk of early mortality in newly diagnosed multiple myeloma (NDMM) patients. In the era of novel agents‐based induction therapy (NAIT), it is unclear whether NAIT can overcome the poor prognosis associated with thrombocytopenia.
Xiaojing Li   +8 more
wiley   +1 more source

A Rare Unusually Aggressive Form of Hereditary Transthyretin Amyloidosis. [PDF]

open access: yesJACC Case Rep
Zhang J   +7 more
europepmc   +1 more source

IgG‐Secreting Lymphoplasmacytic Lymphoma Presenting With Massive Kidney Infiltration

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Various factors related to lymphoplasmacytic lymphoma (LPL) can lead to kidney complications; however, LPL‐related kidney complications are not as well‐described as those with multiple myeloma. Here, we report a case of IgG‐secreting LPL presenting with acute kidney injury owing to direct tumor infiltration.
Yuichi Nakamura   +9 more
wiley   +1 more source

Generating MRI‐Derived CSF Proxy‐Markers to Predict and Visualize Alzheimer's Disease Progression

open access: yesHuman Brain Mapping, Volume 46, Issue 16, November 2025.
Deep learning models trained on structural MRI to predict cerebrospinal fluid‐based amyloid and tau concentrations can generate latent representations (MRI‐derived CSF proxy/surrogate markers) that can be subsequently transferred for Alzheimer's disease detection and risk prediction, bypassing noninvasive testing and enabling regional distribution ...
Anees Abrol   +2 more
wiley   +1 more source

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