Results 1 to 10 of about 242,580 (385)
Chemical Reviews, 2021 Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting either the central nervous system or a variety of peripheral tissues.
Phuong H Nguyen +2 more
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A patient with amyotrophic lateral sclerosis and atypical clinical and electrodiagnostic features: a case report [PDF]
Journal of Medical Case Reports, 2011 Introduction Amyotrophic lateral sclerosis is a rapidly progressive, fatal neurodegenerative disorder for which there is no effective treatment. The diagnosis is dependent on the clinical presentation and consistent electrodiagnostic studies.
Venizelos Alexander +2 more
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Nature Communications, 2023 Amyotrophic lateral sclerosis causes degeneration of motor neurons, resulting in progressive muscle weakness and impairment in motor function. Promising drug development efforts have accelerated in amyotrophic lateral sclerosis, but are constrained by a ...
Anoopum S. Gupta +3 more
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Cervical Spondylotic Myelopathy Mimicking ALS [PDF]
Indian Journal of Physical Medicine & Rehabilitation, 2008 Cervical spondylotic myelopathy presenting with muscle wasting in upper extremities and insignificantsensory loss has been termed as cervical spondylotic amyotrophy. This condition has to be differentiatedfrom Amyotrophic lateral sclerosis which also has
Subramaniam PC, Kumar R, Biswas A
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Ethics in Progress, 2022 This paper aims at analysing the evolution of palliative care in the international context and their role in the path of care for the patient and the family.
Stefania Bastianello +1 more
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Scientific Reports, 2021 Children that have a parent with Amyotrophic Lateral Sclerosis (ALS) suffer from the progressive loss of their beloved ones. During the COVID-19 pandemic, the difficulties faced by these children have increased.
Ines Testoni +5 more
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The landscape of cognitive impairment in superoxide dismutase 1-amyotrophic lateral sclerosis
Neural Regeneration Research, 2023 Although mutations in the superoxide dismutase 1 gene account for only a minority of total amyotrophic lateral sclerosis cases, the discovery of this gene has been crucial for amyotrophic lateral sclerosis research. Since the identification of superoxide
Ilaria Martinelli +6 more
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H63D CG genotype of HFE is associated with increased risk of sporadic amyotrophic lateral sclerosis in a single population [PDF]
Journal of Integrative Neuroscience, 2020 This paper describes the genetic etiology of sporadic amyotrophic lateral sclerosis in a single population. Polymerase chain reaction-restriction fragment length polymorphism and DNA sample sequencing of 3 common HFE gene variants (C282Y and H63D and ...
Qing-Qing Zhang, Hong Jiang, Chun-Yan Li, Ya-Ling Liu, Xin-Ying Tian
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Neural Regeneration Research, 2021 Creatine kinase is a muscle enzyme that has been reported at various levels in different studies involving patients with amyotrophic lateral sclerosis.
Xue-Ping Chen +10 more
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Nature reviews. Drug discovery, 2022 Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of motor neurons. As with all major neurodegenerative disorders, development of disease-modifying therapies has proven challenging for multiple reasons. Nevertheless, ALS
R. Mead +4 more
semanticscholar +1 more source