Results 11 to 20 of about 84,970 (256)

Amyotrophic Lateral Sclerosis

open access: yes, 2020
Chapter to be included in the volume Pragmatic Language Disorders: Complex and Underserved Populations, Ed. Louise Cummings, Springer, 2020. It reviews findings that have contributed to our understanding of pragmatic impairment in ALS.
Ceroni, Mauro, Bambini , Valentina
openaire   +3 more sources

Control in the absence of choice: A qualitative study on decision-making about gastrostomy in people with amyotrophic lateral sclerosis, caregivers, and healthcare professionals.

open access: yesPLoS ONE, 2023
BackgroundGastrostomy is recommended in amyotrophic lateral sclerosis for long-term nutritional support, however, people with amyotrophic lateral sclerosis and healthcare professionals perceive decision-making as complex.MethodTo explore their ...
Remko M van Eenennaam   +6 more
doaj   +1 more source

Microstructural Correlates of Emotional Attribution Impairment in Non-Demented Patients with Amyotrophic Lateral Sclerosis. [PDF]

open access: yesPLoS ONE, 2016
Impairments in the ability to recognize and attribute emotional states to others have been described in amyotrophic lateral sclerosis patients and linked to the dysfunction of key nodes of the emotional empathy network. Microstructural correlates of such
Chiara Crespi   +8 more
doaj   +1 more source

Destination Amyotrophic Lateral Sclerosis [PDF]

open access: yesFrontiers in Neurology, 2021
Amyotrophic Lateral Sclerosis (ALS) is a prototypical neurodegenerative disease characterized by progressive degeneration of motor neurons both in the brain and spinal cord. The constantly evolving nature of ALS represents a fundamental dimension of individual differences that underlie this disorder, yet it involves multiple levels of functional ...
Keon, M   +5 more
openaire   +4 more sources

Amyotrophic Lateral Sclerosis: An Analysis of the Electromyographic Fatigue of the Masticatory Muscles

open access: yesPrague Medical Report, 2022
Amyotrophic lateral sclerosis is a chronic degenerative disease that affects motor neurons, thereby promoting functional changes in the human body.
Ligia Maria Napolitano Gonçalves   +8 more
doaj   +1 more source

Amyotrophic lateral sclerosis [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2009
Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord.
Leigh P Nigel, Wijesekera Lokesh C
openaire   +3 more sources

Amyotrophic lateral sclerosis

open access: yesThe Lancet, 2011
Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative disease of the human motor system. In this Seminar, we summarise current concepts about the origin of the disease, what predisposes patients to develop the disorder, and discuss why all cases of ALS are not the same.
Kiernan, M   +7 more
openaire   +5 more sources

Bridging Silence: A Scoping Review of Technological Advancements in Augmentative and Alternative Communication for Amyotrophic Lateral Sclerosis

open access: yesSclerosis
Background: Amyotrophic lateral sclerosis (ALS) progressively impairs motor function, compromising speech and limiting communication. Augmentative and alternative communication (AAC) is essential to maintain autonomy, social participation, and quality of
Filipe Gonçalves   +4 more
doaj   +1 more source

At-home wearables and machine learning sensitively capture disease progression in amyotrophic lateral sclerosis

open access: yesNature Communications, 2023
Amyotrophic lateral sclerosis causes degeneration of motor neurons, resulting in progressive muscle weakness and impairment in motor function. Promising drug development efforts have accelerated in amyotrophic lateral sclerosis, but are constrained by a ...
Anoopum S. Gupta   +3 more
doaj   +1 more source

Optineurin defects cause TDP43-pathology with autophagic vacuolar formation

open access: yesNeurobiology of Disease, 2021
We previously showed that optineurin (OPTN) mutations lead to the development of amyotrophic lateral sclerosis. The association between OPTN mutations and the pathogenesis of amyotrophic lateral sclerosis remains unclear.
Takashi Kurashige   +11 more
doaj   +1 more source

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