Results 11 to 20 of about 167,403 (289)

Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis [PDF]

open access: yes, 2020
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron degeneration in adults, and several mechanisms underlying the disease pathology have been proposed.
Christoforidou, Eleni   +2 more
core   +1 more source

Lower and upper motor neuron involvement and their impact on disease prognosis in amyotrophic lateral sclerosis

open access: yesNeural Regeneration Research, 2022
Amyotrophic lateral sclerosis is a fatal neurodegenerative disease characterized by progressive muscle wasting, breathing and swallowing difficulties resulting in patient’s death in two to five years after disease onset. In amyotrophic lateral sclerosis,
Maria N Zakharova, Anna A Abramova
doaj   +1 more source

Destination Amyotrophic Lateral Sclerosis [PDF]

open access: yesFrontiers in Neurology, 2021
Amyotrophic Lateral Sclerosis (ALS) is a prototypical neurodegenerative disease characterized by progressive degeneration of motor neurons both in the brain and spinal cord. The constantly evolving nature of ALS represents a fundamental dimension of individual differences that underlie this disorder, yet it involves multiple levels of functional ...
Keon, M   +5 more
openaire   +4 more sources

Early Referral to an ALS Center Reduces Several Months the Diagnostic Delay: A Multicenter-Based Study

open access: yesFrontiers in Neurology, 2020
Objective: To analyze those factors contributing to the diagnostic delay in ALS.Methods: Consecutive ALS patients were categorized as those studied in departmental hospitals and those studied in a referral ALS center.
Marina Martínez-Molina   +16 more
doaj   +1 more source

Amyotrophic lateral sclerosis viewed from a patient’s perspective

open access: yesMonaldi Archives for Chest Disease, 2016
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M. Melazzini
doaj   +1 more source

Amyotrophic Lateral Sclerosis

open access: yes, 2020
Chapter to be included in the volume Pragmatic Language Disorders: Complex and Underserved Populations, Ed. Louise Cummings, Springer, 2020. It reviews findings that have contributed to our understanding of pragmatic impairment in ALS.
Ceroni, Mauro, Bambini , Valentina
openaire   +3 more sources

Different observation period of exercise training in amyotrophic lateral sclerosis patients: A meta-analysis

open access: yesFrontiers in Neurology, 2022
ObjectiveThe purpose of this meta-analysis was to evaluate the effect of more intensive exercise training on the functional ability of patients with amyotrophic lateral sclerosis.MethodsRandomized controlled trials on exercise training in amyotrophic ...
Baohua Zhou   +8 more
doaj   +1 more source

Control in the absence of choice: A qualitative study on decision-making about gastrostomy in people with amyotrophic lateral sclerosis, caregivers, and healthcare professionals.

open access: yesPLoS ONE, 2023
BackgroundGastrostomy is recommended in amyotrophic lateral sclerosis for long-term nutritional support, however, people with amyotrophic lateral sclerosis and healthcare professionals perceive decision-making as complex.MethodTo explore their ...
Remko M van Eenennaam   +6 more
doaj   +1 more source

Amyotrophic lateral sclerosis modifies progenitor neural proliferation in adult classic neurogenic brain niches

open access: yesBMC Neurology, 2017
Background Adult neurogenesis persists through life at least in classic neurogenic niches. Neurogenesis has been previously described as reduced in neurodegenerative diseases.
Lucía Galán   +4 more
doaj   +1 more source

Dysphagia in amyotrophic lateral sclerosis: impact on patient behavior, diet adaptation, and riluzole management [PDF]

open access: yes, 2017
This retrospective study aimed to investigate the clinical features associated with deteriorated swallow in amyotrophic lateral sclerosis (ALS) patients with spinal and bulbar onset, describe the modification of diet and liquid intake, and assess the ...
CAMBIERI, CHIARA   +7 more
core   +1 more source

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