Results 151 to 160 of about 84,495 (257)

Genetic contributions to mitochondrial dysfunction in amyotrophic lateral sclerosis etiology. [PDF]

HGG Adv
Russell ND, Downie JM, Bromberg MB, Pulst SM, Jorde LB.   +4 more
europepmc   +1 more source

Safety evaluation of Tofersen in amyotrophic lateral sclerosis based on the FAERS database. [PDF]

Front Neurol
Xiao X, Hao G, Wan P, Hou W.
europepmc   +1 more source

The Emotional Experiences of Healthcare Professionals Working in Amyotrophic Lateral Sclerosis: A Systematic Review

Muscle &Nerve, EarlyView.
ABSTRACT Healthcare professionals (HCPs) working with people living with amyotrophic lateral sclerosis (ALS) are often exposed to emotive circumstances including end of life care, trauma, loss, and death. Existing reviews have explored the emotional experiences of people living with ALS and their carers but have largely ignored healthcare staff and the
Young Chan, Sarah Creer, Jess Mere, Alys Wyn Griffiths, Charlotte Wright, Esther V. Hobson, Christopher J. McDermott, Emily J. Mayberry   +7 more
wiley   +1 more source

A nomogram for estimating baseline respiratory insufficiency in patients with amyotrophic lateral sclerosis. [PDF]

Ann Med
Wang H, Li G, Liang F, Xia X, Zhang W, Fan Z.   +5 more
europepmc   +1 more source

No Evidence for an Association Between DIP2B Repeat Expansion and Neurological Disease

Movement Disorders, EarlyView.
Chia‐Ying Ko, Leon Schütz, Thomas Braun, Elena Buena‐Atienza, Nicolas Casadei, Danique Beijer, Ludger Schöls, Tobias B. Haack, Stephan Ossowski, Holger Hengel   +9 more
wiley   +1 more source

Optimizing Research Operations and Resource Utilization in ALS Care: Insights From the Tofersen Antisense Oligonucleotide Expanded Access Protocol

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Tofersen is a gene‐targeted therapy for individuals with superoxide dismutase 1 (SOD1) (+) amyotrophic lateral sclerosis (ALS). Prior to U.S. Food and Drug Administration (FDA) approval, tofersen was made available through expanded access protocol.
Alison Wheeler, Kush Mehta, Danica Sanders, Cathy Chin, Hannah Zivalic, Judith Carey, Alexandra McCaffrey, Pravin Pant, Carl Lewenhaupt, Sarah Luppino, Gabriel Jacobs, Shea Golden, Ryan Gifford, Erica Scirocco, Mackenzie Keegan, Munaf Hatem, Taravat Yazdanian, Sanem P. Uysal, Natalie Susco, Shauna Schwartzman, Karen Branch, Kathryn E. Hall, Joanna Barnas, Jenny Lam, Jennifer Hagar, Carol Ann Hannan, Sabrina Paganoni, James D. Berry, Mark Garret, Jennifer Scalia, Suma Babu   +30 more
wiley   +1 more source

Usefulness of Information and Communication Technology‐Based Patient Information Sharing System in Supporting Patients With Intractable Neurological Diseases

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Multidisciplinary collaboration is crucial for patients with incurable neurological diseases. However, sharing information among medical staff across institutions is challenging. Our cloud‐based patient information sharing system uses information and communication technology to facilitate the sharing of patient information among ...
Yui Kamijo, Akiyo Hineno, Gaku Okumura, Yoshiki Sekijima, Akinori Nakamura   +4 more
wiley   +1 more source

Author Correction: Autoimmune response to C9orf72 protein in amyotrophic lateral sclerosis. [PDF]

Nature
Michaelis T, Lindestam Arlehamn CS, Johansson E, Frazier A, Williams GP, Berry JD, Cudkowicz M, Goyal NA, Fournier C, Snyder A, Kwan JY, Crook J, Phillips EJ, Mallal SA, Ravits J, Marder KS, Sidney J, Sulzer D, Sette A.   +18 more
europepmc   +1 more source

Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease

Neuroprotection, EarlyView.
In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong, Andrew Octavian Sasmita, Rhun Yian Koh, Anna Pick Kiong Ling   +3 more
wiley   +1 more source

Long-Term Tofersen in SOD1 Amyotrophic Lateral Sclerosis. [PDF]

JAMA Neurol
Miller TM, Cudkowicz ME, Shaw PJ, Genge A, Sobue G, Bucelli RC, Chiò A, Van Damme P, Ludolph AC, Glass JD, Andrews JA, Babu S, Benatar M, McDermott CJ, Salachas F, Bruneteau G, Al-Chalabi A, Amorin M, Nestorov I, Graham D, Lin L, Sun P, McNeill M, Malek S, Inra J, Garafalo S, Fradette S, VALOR and OLE Working Group.   +27 more
europepmc   +1 more source