Results 141 to 150 of about 84,495 (257)

Plasma isomiRs as Candidate Biomarkers for Amyotrophic Lateral Sclerosis. [PDF]

Neurol Genet
Magee RG, Van Deerlin VM, McMillan CT, Lee EB, Elman LB, Irwin DJ, Mourelatos Z.   +6 more
europepmc   +1 more source

SNR‐Efficient Inhomogeneous Magnetization Transfer (ihMT) for Clinical Applications at 7 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Inhomogeneous MT (ihMT) is an MRI modality sensitive to Myelin, the lipid‐rich membrane surrounding the axons. A novel ihMT saturation strategy and its associated B1+$$ {\mathrm{B}}_1^{+} $$ correction at UHF are proposed. The aim is to generate a strong ihMT effect within a clinically compatible scan time while complying with SAR ...
Timothy Anderson, Niklas Wallstein, Lucas Soustelle, Thomas Troalen, Gopal Varma, David C. Alsop, Maxime Guye, Guillaume Duhamel, Olivier M. Girard   +8 more
wiley   +1 more source

Reachable Workspace as a Clinical Outcome for Upper Extremity Function: A Narrative Review

Muscle &Nerve, EarlyView.
ABSTRACT Motion sensing technology can be utilized to capture detailed upper extremity (UE) motion to reconstruct an individual's three‐dimensional (3D) reachable workspace (RWS). The RWS can be quantified as relative surface area (RSA), providing an innovative surrogate measure to assess UE mobility and function.
Jay J. Han, Lawrence J. Hayward, Christina Adams, Juan Perez‐Ibarra   +3 more
wiley   +1 more source

Excitotoxicity in amyotrophic lateral sclerosis: a key pathogenic mechanism. [PDF]

Brain Commun
Silva-Hucha S, Hernández RG, Baena-López D, Fernández de Sevilla ME, Paradas C, Morcuende S.   +5 more
europepmc   +1 more source

Mimickers of Amyotrophic Lateral Sclerosis

Annals of Indian Academy of Neurology, 2019
Ayush Dubey, Shubham Dubey
openaire   +3 more sources

Neuroprotective Effects of RNS60 in TDP‐43 Pathology‐Associated Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction TDP‐43 pathology is broadly observed in the cerebral cortex of patients with amyotrophic lateral sclerosis (ALS). RNS60, an experimental treatment for acute ischemic stroke and ALS, enhanced mitochondrial biogenesis and function in other preclinical models.
Danny R. Vesevick, Supurna Ghosh, Andreas Kalmes, P. Hande Ozdinler, Mukesh Gautam   +4 more
wiley   +1 more source

Exercise pressor reflex in Amyotrophic lateral sclerosis patients. [PDF]

Sci Rep
Saeki Y, Nakamura N, Hayashi N.
europepmc   +1 more source

Embedding Palliative Care Clinicians in ALS Teams Improves ALS Clinicians' Confidence in Their Patient Management and Satisfaction With Palliative Care

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Specialty palliative care (SPC) can improve symptoms and well‐being for people living with ALS. Few studies capture how ALS clinicians utilize or are impacted by SPC. We sought to understand how the presence of SPC clinicians on ALS teams impacts ALS clinicians' referrals to and satisfaction with SPC.
Astrid Grouls, Yaowaree L. Leavell, Ambereen K. Mehta, Gayle Kojimoto, David L. O'Riordan, Samuel Maiser, Benzi M. Kluger, Steven Z. Pantilat, Kara E. Bischoff   +8 more
wiley   +1 more source

A next-generation HDAC6 inhibitor for amyotrophic lateral sclerosis and frontotemporal dementia. [PDF]

Brain
James RE, Bekier M, Lee PJ, Schroeder FA, Evans LT, Wagner FF, Hickman D, Richardson T, Hatzipetros T, Vieira F, Callizot N, Modi S, Hooker JM, Kranz JE, Brown RH, Barmada SJ, Gilbert TM.   +16 more
europepmc   +1 more source

The Flail Limb Syndrome

Muscle &Nerve, EarlyView.
ABSTRACT The flail limb syndrome is primarily a lower motor neuron disorder that initially affects proximal arm muscles (flail arm syndrome—FAS) or distal leg muscles (flail leg syndrome—FLS). Both were recognized early on (1886 for FAS and 1918 for FLS) as somewhat distinct from classic amyotrophic lateral sclerosis (ALS).
Mark B. Bromberg
wiley   +1 more source