Results 211 to 220 of about 235,642 (386)

Nerve conduction velocities of single thenar motor axons based on the automated analysis of F waves in amyotrophic lateral sclerosis [PDF]

, 1998
Kevin J. Felice
openalex   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, EarlyView.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

BRANCHED-CHAIN AMINOACIDS IN AMYOTROPHIC LATERAL SCLEROSIS

, 1988
R J Guiloff, J Emami, M During, Andrew Freese, Andreas Plaitakis, John Mandeli, Jeffrey A. Smith, M. D. Yahr, Andreas Plaitakis, P. Shashidharan, S. Malessa, Nigel Leigh, Oleh Hornykiewicz   +12 more
openalex   +1 more source

Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1 [PDF]

, 1998
Jiming Kong, Zuoshang Xu
openalex   +1 more source

State of play in amyotrophic lateral sclerosis genetics

Nature Neuroscience, 2013
A. Renton, A. Chiò, B. Traynor
semanticscholar   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

Exploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li, Haonan Xing, Abid Naeem, Kaiyue Zhang, Aiping Zheng, Yuanyu Huang, Mei Lu   +6 more
wiley   +1 more source

Supranuclear paralysis preventing lid closure in amyotrophic lateral sclerosis.

, 1989
N Sunohara, Masakuni Mukoyama, Hitomi FUNAMOTO, Nobuyuki Kamei, H Tomi, E Satoyoshi   +5 more
openalex   +2 more sources

Decreased Zinc Affinity of Amyotrophic Lateral Sclerosis‐Associated Superoxide Dismutase Mutants Leads to Enhanced Catalysis of Tyrosine Nitration by Peroxynitrite [PDF]

, 1997
John P. Crow, Jacinda B. Sampson, Yingxin Zhuang, J. Anthony Thompson, Joseph S. Beckman   +4 more
openalex   +1 more source

Dietary Exposure to Mercury and Arsenic From Traditional Qatari Foods: Implications for Food Safety and Public Health

Food Safety and Health, EarlyView.
In the Qatari cuisine, seafood showed significantly elevated mercury concentrations, whereas arsenic was more evenly distributed across the different foods. Although arsenic exposure was low (HQ < 0.2), mercury posed a high risk (HQ 7.9–9.3; HI > 8), highlighting seafood as the dominant dietary source of heavy metal exposure. ABSTRACT Heavy metals have
Dalal AlAnsari, Khaloud Asheer, Loubna Sisouana, Shahad AlQashouti, Aya Hamdan, Tahra ElObeid   +5 more
wiley   +1 more source

Educational lecture on amyotrophic lateral sclerosis.

, 1987
Hiroshi Tsukagoshi
openalex   +2 more sources