Results 231 to 240 of about 995,258 (307)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Rheological and Technological Design of Texture-Modified Food Systems for Dysphagia Management in Amyotrophic Lateral Sclerosis. [PDF]

J Texture Stud
Konarbayeva Z.
europepmc   +1 more source

Vitamin E serum levels and controlled supplementation and risk of amyotrophic lateral sclerosis

Kuncl, Ralph W., Weinstein, Stephanie J., Virtamo, Jarmo, Albanes, Demetrius, Malila, Nea, Freedman, D. Michal   +5 more
core   +1 more source

White matter abnormalities in amyotrophic lateral sclerosis: a free water imaging study. [PDF]

Front Neurosci
Liu Z, Yang H, Cui J, Guan Z, Gao D, Feng P, Yang H, Li W, Zhao Y, Yang Q, Zheng X, Liu Q, Geng Z.   +12 more
europepmc   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Mortality From Amyotrophic Lateral Sclerosis in Finland 1987-2022. [PDF]

Eur J Neurol
Laine M, Raitanen J, Auvinen A.
europepmc   +1 more source

Ageing alters cysteine oxidation‐regulated redox signalling in skeletal muscle: Integrative omics and AI‐based structural predictions

Experimental Physiology, EarlyView.
Abstract Ageing is associated with loss of skeletal muscle mass and strength (sarcopenia) and disrupted redox homeostasis. Redox signalling is essential for muscle adaptation, yet the mechanisms by which ageing disrupts cysteine‐based regulation are poorly defined. The drivers of site‐specific reactivity and signalling specificity in aged muscle remain
Ufuk Ersoy, Malcolm J. Jackson
wiley   +1 more source

King's stages of amyotrophic lateral sclerosis: an 18F-FDG-PET study of brain connectivity. [PDF]

Brain
Di Pede F, Cabras S, Manera U, Vasta R, Zocco G, Minerva E, Matteoni E, De Mattei F, Pellegrino G, Palumbo F, Pascariu D, Callegaro S, Maccabeo A, Polverari G, Martino A, Giuliani A, Moglia C, Calvo A, Chiò A, Pagani M, Canosa A.   +20 more
europepmc   +1 more source

Muscle cramp susceptibility is associated with muscle‐specific modulation of human motoneuron discharge patterns

Experimental Physiology, EarlyView.
Abstract Muscle cramps are painful, involuntary contractions thought to arise from altered spinal motoneuron excitability, potentially involving persistent inward currents (PICs). We examined whether cramp susceptibility is associated with altered PIC‐related motoneuron behaviour and whether electrically induced cramp modifies these estimates.
Timothée Popesco, Romain Dos Santos, Ilan Cassoli, Gabriel S. Trajano, Gregory E. P. Pearcey, Nicola A. Maffiuletti, Chris Donnelly, Bengt Kayser, Nicolas Place   +8 more
wiley   +1 more source

Alzheimer's Disease Co-Pathology and Cognitive Impairment in Amyotrophic Lateral Sclerosis. [PDF]

Ann Neurol
Kasper E, Lehto A, Jürs A, Nordmann N, Peters O, Hellmann J, Priller J, Spruth EJ, Petzold GC, Voigt I, Weydt P, Bernsen S, Dinter E, Falkenburger B, Günther R, Düzel E, Glanz W, Synofzik M, Beichert L, Spottke A, Wagner M, Brosseron F, Schmid MC, Halle A, Herms J, Schneider A, Teipel S, Prudlo J, Neumann M, Hermann A.   +29 more
europepmc   +1 more source