Results 31 to 40 of about 242,580 (385)

Microstructural Correlates of Emotional Attribution Impairment in Non-Demented Patients with Amyotrophic Lateral Sclerosis. [PDF]

open access: yesPLoS ONE, 2016
Impairments in the ability to recognize and attribute emotional states to others have been described in amyotrophic lateral sclerosis patients and linked to the dysfunction of key nodes of the emotional empathy network. Microstructural correlates of such
Chiara Crespi   +8 more
doaj   +1 more source

Amyotrophic Lateral Sclerosis: An Analysis of the Electromyographic Fatigue of the Masticatory Muscles

open access: yesPrague Medical Report, 2022
Amyotrophic lateral sclerosis is a chronic degenerative disease that affects motor neurons, thereby promoting functional changes in the human body.
Ligia Maria Napolitano Gonçalves   +8 more
doaj   +1 more source

Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
core   +1 more source

Sleep disorders of insomnia type in patients with amyotrophic lateral sclerosis

open access: yesНервно-мышечные болезни, 2017
Objective: to evaluate the rate of sleep disorders of insomnia type among patients with amyotrophic lateral sclerosis (ALS) and to study the connection between these disorders and clinical characteristics of the disease. Materials and methods.
G. N. Levitskiy, M. G. Poluektov
doaj   +1 more source

Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases

open access: yesBrain : a journal of neurology, 2021
Significant progress has been made in understanding the pre-symptomatic phase of amyotrophic lateral sclerosis. While much is still unknown, advances in other neurodegenerative diseases offer valuable insights.
M. Benatar   +23 more
semanticscholar   +1 more source

Dysphagia in amyotrophic lateral sclerosis: impact on patient behavior, diet adaptation, and riluzole management [PDF]

open access: yes, 2017
This retrospective study aimed to investigate the clinical features associated with deteriorated swallow in amyotrophic lateral sclerosis (ALS) patients with spinal and bulbar onset, describe the modification of diet and liquid intake, and assess the ...
CAMBIERI, CHIARA   +7 more
core   +1 more source

Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND Sodium phenylbutyrate and taurursodiol have been found to reduce neuronal death in experimental models. The efficacy and safety of a combination of the two compounds in persons with amyotrophic lateral sclerosis (ALS) are not known.
S. Paganoni   +58 more
semanticscholar   +1 more source

Mild motor impairment as prodromal state in amyotrophic lateral sclerosis: a new diagnostic entity

open access: yesBrain : a journal of neurology, 2022
Amyotrophic lateral sclerosis, when viewed as a biological entity rather than a clinical syndrome, probably evolves along a continuum, with the initial clinically silent phase eventually evolving into clinically manifest amyotrophic lateral sclerosis ...
M. Benatar   +7 more
semanticscholar   +1 more source

Noninvasive ¹³C-octanoic acid breath test shows delayed gastric emptying in patients with amyotrophic lateral sclerosis [PDF]

open access: yes, 1999
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive loss of motor neurons. However, ALS has been recognized to also involve non-motor systems.
Folwaczny, Christian   +6 more
core   +1 more source

Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis

open access: yesFrontiers in Molecular Neuroscience, 2019
TAR DNA binding protein 43 (TDP-43) is a versatile RNA/DNA binding protein involved in RNA-related metabolism. Hyper-phosphorylated and ubiquitinated TDP-43 deposits act as inclusion bodies in the brain and spinal cord of patients with the motor neuron ...
A. Prasad   +4 more
semanticscholar   +1 more source

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