Results 31 to 40 of about 235,642 (386)

Botulinum toxin for the treatment of lower limb cramp pain in patients with Amyotrophic Lateral Sclerosis [PDF]

, 2020
Background: Muscle cramps and pain associated with them can be seen in patients with amyotrophic lateral sclerosis (ALS) and are known to reduce the quality of life. Pharmacological treatment may not benefit all patients in treating these cramps.
Govindarajan, Raghav, Mehta, Tejas, Sommers, Richard   +2 more
core   +2 more sources

Amyotrophic lateral sclerosis

The Lancet, 2011
Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative disease of the human motor system. In this Seminar, we summarise current concepts about the origin of the disease, what predisposes patients to develop the disorder, and discuss why all cases of ALS are not the same.
Kiernan, M, Vucic, S, Cheah, B, Turner, M, Eisen, A, Hardiman, O, Burrell, JR, Zoing, M   +7 more
openaire   +5 more sources

Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord

Brain : a journal of neurology, 2022
Aberrant self-assembly and toxicity of wild-type and mutant superoxide dismutase 1 (SOD1) has been widely examined in silico, in vitro and in transgenic animal models of amyotrophic lateral sclerosis.
B. G. Trist, Sian Genoud, Stéphane Roudeau, Alexander Rookyard, Amr H. Abdeen, Veronica Cottam, D. Hare, Melanie Y. White, Jens Altvater, J. Fifita, A. Hogan, N. Grima, I. Blair, K. Kysenius, P. Crouch, A. Carmona, Yann Rufin, S. Claverol, Stijn J. M. Van Malderen, G. Falkenberg, D. Paterson, Bradley N. Smith, C. Troakes, C. Vance, C. Shaw, S. Al-Sarraj, S. Cordwell, G. Halliday, R. Ortega, K. Double   +29 more
semanticscholar   +1 more source

[Amyotrophic lateral sclerosis]. [PDF]

Nederlands tijdschrift voor tandheelkunde, 2010
Amyotrophic lateral sclerosis is one of the most severe and disabling diseases of the nervous system. Amyotrophic lateral sclerosis leads to the progressive weakening of the muscles in the arms, legs, face, mouth and trunk. The onset of the disease is insidious, starting with weakness in the hands or feet or with slurred speech.
Veldink, J.H., Weikamp, J.G., Schelhaas, H.J., Berg, L.H. van den   +3 more
  +8 more sources

Amyotrophic lateral sclerosis viewed from a patient’s perspective

Monaldi Archives for Chest Disease, 2016
-
M. Melazzini
doaj   +1 more source

Different observation period of exercise training in amyotrophic lateral sclerosis patients: A meta-analysis

Frontiers in Neurology, 2022
ObjectiveThe purpose of this meta-analysis was to evaluate the effect of more intensive exercise training on the functional ability of patients with amyotrophic lateral sclerosis.MethodsRandomized controlled trials on exercise training in amyotrophic ...
Baohua Zhou, Jiajun Wei, Yanli Zhang, Yue Liu, Shuhui Shan, Shan Ye, Baohua Li, Dongsheng Fan, Yongmei Luo   +8 more
doaj   +1 more source

Eye Tracking Impact on Quality-of-Life of ALS Patients [PDF]

, 2008
Chronic neurological disorders in their advanced phase are characterized by a progressive loss of mobility (use of upper and lower limbs), speech and social life.
And Vignola, A., Calvo, A., Castellina, Emiliano, Chiò, A., Corno, Fulvio, Farinetti, Laura, Ghiglione, P., Pasian, V.   +7 more
core   +1 more source

Control in the absence of choice: A qualitative study on decision-making about gastrostomy in people with amyotrophic lateral sclerosis, caregivers, and healthcare professionals.

PLoS ONE, 2023
BackgroundGastrostomy is recommended in amyotrophic lateral sclerosis for long-term nutritional support, however, people with amyotrophic lateral sclerosis and healthcare professionals perceive decision-making as complex.MethodTo explore their ...
Remko M van Eenennaam, Neele Rave, Willeke J Kruithof, Esther T Kruitwagen-van Reenen, Leonard H van den Berg, Johanna A Visser-Meily, Anita Beelen   +6 more
doaj   +1 more source

Amyotrophic Lateral Sclerosis: An Analysis of the Electromyographic Fatigue of the Masticatory Muscles

Prague Medical Report, 2022
Amyotrophic lateral sclerosis is a chronic degenerative disease that affects motor neurons, thereby promoting functional changes in the human body.
Ligia Maria Napolitano Gonçalves, Selma Siéssere, Flávia Argentato Cecilio, Jaime Eduardo Cecilio Hallak, Paulo Batista de Vasconcelos, Wilson Marques Júnior, Isabela Hallak Regalo, Marcelo Palinkas, Simone Cecilio Hallak Regalo   +8 more
doaj   +1 more source

Amyotrophic lateral sclerosis modifies progenitor neural proliferation in adult classic neurogenic brain niches

BMC Neurology, 2017
Background Adult neurogenesis persists through life at least in classic neurogenic niches. Neurogenesis has been previously described as reduced in neurodegenerative diseases.
Lucía Galán, Ulises Gómez-Pinedo, Antonio Guerrero, Jose Manuel García-Verdugo, Jorge Matías-Guiu   +4 more
doaj   +1 more source