Microstructural Correlates of Emotional Attribution Impairment in Non-Demented Patients with Amyotrophic Lateral Sclerosis. [PDF]
PLoS ONE, 2016 Impairments in the ability to recognize and attribute emotional states to others have been described in amyotrophic lateral sclerosis patients and linked to the dysfunction of key nodes of the emotional empathy network. Microstructural correlates of such
Chiara Crespi +8 more
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Destination Amyotrophic Lateral Sclerosis [PDF]
Frontiers in Neurology, 2021 Amyotrophic Lateral Sclerosis (ALS) is a prototypical neurodegenerative disease characterized by progressive degeneration of motor neurons both in the brain and spinal cord. The constantly evolving nature of ALS represents a fundamental dimension of individual differences that underlie this disorder, yet it involves multiple levels of functional ...
Keon, M +5 more
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Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis [PDF]
, 2010 The finding of TDP-43 as a major component of ubiquitinated protein inclusions in amyotrophic lateral sclerosis (ALS) has led to the identification of 30 mutations in the transactive response-DNA binding protein (TARDBP) gene, encoding TDP-43.
A Yokoseki +46 more
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Sleep disorders of insomnia type in patients with amyotrophic lateral sclerosis
Нервно-мышечные болезни, 2017 Objective: to evaluate the rate of sleep disorders of insomnia type among patients with amyotrophic lateral sclerosis (ALS) and to study the connection between these disorders and clinical characteristics of the disease. Materials and methods.
G. N. Levitskiy, M. G. Poluektov
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Dysphagia in amyotrophic lateral sclerosis: impact on patient behavior, diet adaptation, and riluzole management [PDF]
, 2017 This retrospective study aimed to investigate the clinical features associated with deteriorated swallow in amyotrophic lateral sclerosis (ALS) patients with spinal and bulbar onset, describe the modification of diet and liquid intake, and assess the ...
CAMBIERI, CHIARA +7 more
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Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.
New England Journal of Medicine, 2020 BACKGROUND Sodium phenylbutyrate and taurursodiol have been found to reduce neuronal death in experimental models. The efficacy and safety of a combination of the two compounds in persons with amyotrophic lateral sclerosis (ALS) are not known.
S. Paganoni +58 more
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Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases
Brain : a journal of neurology, 2021 Significant progress has been made in understanding the pre-symptomatic phase of amyotrophic lateral sclerosis. While much is still unknown, advances in other neurodegenerative diseases offer valuable insights.
M. Benatar +23 more
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Noninvasive ¹³C-octanoic acid breath test shows delayed gastric emptying in patients with amyotrophic lateral sclerosis [PDF]
, 1999 Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive loss of motor neurons. However, ALS has been recognized to also involve non-motor systems.
Folwaczny, Christian +6 more
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Egyptian Journal of Anaesthesia, 2018 Amyotrophic lateral sclerosis, which is also known as motor neuron disease, is a chronic neurodegenerative disease characterized by progressive muscular weakness, respiratory muscle disability, and eventual death.
Bo-Ra Kim +3 more
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Nature Communications, 2023 Amyotrophic lateral sclerosis causes degeneration of motor neurons, resulting in progressive muscle weakness and impairment in motor function. Promising drug development efforts have accelerated in amyotrophic lateral sclerosis, but are constrained by a ...
Anoopum S. Gupta +3 more
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