The insulin-like growth factors: Potential anabolic agents for the skeleton
Johansson, Anna G,, Rosen, CJ
core +5 more sources
Case Report: Reopening the anabolic window - romosozumab added to ongoing denosumab for severe osteoporosis in two kidney transplant recipients. [PDF]
Barbuto S +9 more
europepmc +1 more source
ABSTRACT Introduction Cancer cachexia is characterized by skeletal muscle loss, poor nutrition, and systemic inflammation and is common in head and neck cancer. We evaluated whether the Cachexia Index (CXI) predicts treatment toxicity and survival in HPV‐negative HNSCC.
Gianluca Savoia +11 more
wiley +1 more source
From Risk to Treatment: Clinical Updates in Osteoporosis Management. [PDF]
Alchi K, Chan A.
europepmc +1 more source
Measuring Temporal Variations of Nucleotide Pools in Microbial Granular Biofilm
The developed metabolomics workflow enables quantification of energy nucleotides in complex microbial biofilms. The method provides a foundation for investigating rapid metabolic responses to dynamic environmental conditions. ABSTRACT Microbial communities often face environmental fluctuations that occur on timescales much shorter than their growth ...
Jitske M. van Ede +3 more
wiley +1 more source
Gut virome orchestrates nitrogen partitioning between the host and microbiome
Under normal protein intake, lytic phages promote bacterial turnover, releasing microbial nitrogen that can be assimilated by the host and thereby revealing phage‐mediated lysis as a potential pathway for host nutrient acquisition. Under protein restriction, however, phages shift toward a lysogenic strategy, reducing bacterial death and microbial ...
Shujie Xu +7 more
wiley +1 more source
Longitudinal osteoporosis therapy: treat-to-target and sequential strategies-a narrative review. [PDF]
Tskhakaia I, Danila MI.
europepmc +1 more source
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source
Phase-Specific Nutritional Therapy in Critical Illness: When Protein May Help and When It May Harm, from Acute Metabolic Adaptation to Post-ICU Recovery. [PDF]
Stoian M +6 more
europepmc +1 more source
Perspectives of High‐Resolution Mass Spectrometry in Soil Science
ABSTRACT Soil biogeochemical research requires specific, sensitive, and accurate methods to identify and quantify organic molecules in order to trace biochemical processes and assess element cycling in complex, heterogenous systems. High‐resolution mass spectrometry (HRMS) has evolved into a transformative tool for unraveling the complex chemical ...
Bruno Glaser +11 more
wiley +1 more source

