Results 21 to 30 of about 167,379 (210)

Definition and management of very high fracture risk in women with postmenopausal osteoporosis: a position statement from the Brazilian Society of Endocrinology and Metabolism (SBEM) and the Brazilian Association of Bone Assessment and Metabolism (ABRASSO)

Archives of Endocrinology and Metabolism, 2022
Several drugs are available for the treatment of osteoporosis in postmenopausal women. Over the last decades, most patients requiring pharmacological intervention were offered antiresorptive drugs as first-line therapy, while anabolic agents were ...
Barbara C. Silva, Miguel Madeira, Catarina Brasil d’Alva, Sergio Setsuo Maeda, Narriane Chaves Pereira de Holanda, Monique Nakayama Ohe, Vera Szejnfeld, Cristiano A. F. Zerbini, Francisco José Albuquerque de Paula, Francisco Bandeira   +9 more
doaj   +1 more source

Lipid peroxidation and apoptotic response in rat brain areas induced by long-term administration of nandrolone: the mutual crosstalk between ROS and NF-kB [PDF]

, 2016
The aim of this study was to evaluate the played by oxidative stress in the apoptotic response in different brain areas of rats chronically treated with supra-physiological doses of nandrolone decanoate (ND).
Busardo', FRANCESCO PAOLO, Cantatore, Santina, Cerretani, Daniela, Fineschi, Vittorio, Frati, Paola, Moltoni, Laura, Neri, Margherita, Pomara, Cristoforo, Riezzo, Irene, Turillazzi, Emanuela   +9 more
core   +2 more sources

The why and how of sequential and combination therapy in osteoporosis. A review of the current evidence

Archives of Endocrinology and Metabolism, 2022
It is now well recognized that over the lifetime of a patient with osteoporosis, more than one medication will be needed to treat the disease and to decrease fracture risk.
Manju Chandran
doaj   +1 more source

Deletion of a Single beta-Catenin Allele in Osteocytes Abolishes the Bone Anabolic Response to Loading [PDF]

, 2014
The Wnt/β-catenin signaling pathway is essential for bone cell viability and function and for skeletal integrity. To determine if β-catenin in osteocytes plays a role in the bone anabolic response to mechanical loading, 18- to 24-week-old osteocyte β ...
Akhter, Armstrong, Armstrong, Babij, Bodine, Bodine, Bonewald, Bouxsein, Boyden, Case, Choi, Dallas, Dempster, Diarra, Doube, Galea, Glass, Gong, Hens, Holmen, Holmen, Javaheri, Johnson, Johnson, Johnson, Kamel, Kato, Kitase, Korecki, Kramer, Lau, Li, Little, Logan, Lu, Monga, Nakashima, Nathke, Nusse, Pinson, Polakis, Reya, Robinson, Santos, Sawakami, Saxon, Schneider, Sen, Srivastava, Sunters, Wijenayaka, Xing, Xiong, Yao   +53 more
core   +2 more sources

Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model [PDF]

, 2013
© 2013 Peake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Achan, P, Bader, DL, Chowdhury, TT, Hobbs, AJ, Moyes, AJ, Peake, N, Ramachandran, M, Salter, DM, Su, N   +8 more
core   +3 more sources

Effects of Methoxyisoflavone, Ecdysterone, and Sulfo-Polysaccharide Supplementation on Training Adaptations in Resistance-Trained Males

Journal of the International Society of Sports Nutrition, 2006
Purpose Methoxyisoflavone (M), 20-hydroxyecdysone (E), and sulfo-polysaccharide (CSP3) have been marketed to athletes as dietary supplements that can increase strength and muscle mass during resistance-training.
Greenwood Michael, Rasmussen Chris J, Kerksick Chad, Campbell Bill I, Taylor Lemuel W, Wilborn Colin D, Kreider Richard B   +6 more
doaj   +1 more source

Tracking internet interest in anabolic-androgenic steroids using Google Trends [PDF]

, 2018
Background: There is a perception that the prevalence of anabolic-androgenic steroid (AAS) use is increasing in the UK, with consequent individual and public health risks.
Mccann, Mark, Tay Wee Teck, Joseph
core   +1 more source

Severe Cardiac and Metabolic Pathology Induced by Steroid Abuse in a Young Individual

Diagnostics, 2021
Androgenic-Anabolic Steroids (AAS) abuse is known to play an important role in causing the systemic inflammatory response and multiple-organ dysfunction in healthy individuals. Although many of the undesirable effects of steroid abuse have been reported,
Adrian Tirla, Cosmin Mihai Vesa, Simona Cavalu   +2 more
doaj   +1 more source

Novel individualized power training protocol preserves physical function in adult and older mice [PDF]

, 2019
Sarcopenia, the age-related loss of muscle mass and strength, contributes to frailty, functional decline, and reduced quality of life in older adults. Exercise is a recognized therapy for sarcopenia and muscle dysfunction, though not a cure. Muscle power
Fandrey, Katie R., Graber, Ted G., Thompson, LaDora V.   +2 more
core   +1 more source

Position-Specific Metabolic Probing and Metagenomics of Microbial Communities Reveal Conserved Central Carbon Metabolic Network Activities at High Temperatures

Frontiers in Microbiology, 2019
Temperature is a primary driver of microbial community composition and taxonomic diversity; however, it is unclear to what extent temperature affects characteristics of central carbon metabolic pathways (CCMPs) at the community level.
Scott C. Thomas, Kevin O. Tamadonfar, Cale O. Seymour, Dengxun Lai, Jeremy A. Dodsworth, Senthil K. Murugapiran, Emiley A. Eloe-Fadrosh, Paul Dijkstra, Brian P. Hedlund, Brian P. Hedlund   +9 more
doaj   +1 more source