Results 21 to 30 of about 116,695 (256)
Differential activation of AKT isoforms by growth factors in human myotubes
Physiological Reports, 2023 AKT signaling plays a crucial role in muscle physiology, and is activated by stimuli, including insulin, growth factors, and exercise. Three AKT isoforms have been identified in mammals, and they possess both distinct and redundant functions. However, it
Brandon M. Roberts +2 more
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Frontiers in Pharmacology, 2021 Background: The driving force behind osteoarthritis (OA) pathogenesis is an anabolic-catabolic (a/c) imbalance. Melatonin (MT) is a key player in maintaining a/c stability and mitigates OA pathogenesis, but mechanisms underlying its effects remain poorly
Dewan Md. Sumsuzzman +17 more
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Ecdysteroids: A novel class of anabolic agents? [PDF]
, 2015 Increasing numbers of dietary supplements with ecdysteroids are marketed as “natural anabolic agents”. Results of recent studies suggested that their anabolic effect is mediated by estrogen receptor (ER) binding. Within this study the anabolic potency of
J Hengevoss +10 more
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Remote Sensing, 2020 As an open artificial ecosystem, the development of a city requires the continuous input and output of material and energy, which is called urban metabolism, and includes catabolic (material-flow) and anabolic (material-accumulation) processes.
Shuqi He +4 more
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Journal of the International Society of Sports Nutrition, 2022 Objective This study examined the effects of short-term betaine supplementation on muscle endurance, plasma lactate, testosterone and cortisol levels, and the testosterone to cortisol (T/C) ratio in response to acute resistance exercise (RE).
Hamid Arazi +4 more
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Senkyunolide A inhibits the progression of osteoarthritis by inhibiting the NLRP3 signalling pathway
Pharmaceutical Biology, 2022 Context Osteoarthritis (OA) is a degenerative disease. Senkyunolide A (SenA) is an important phthalide from Ligusticum chuanxiong Hort (Umbelliferae) with anti-spasmodic and neuroprotective effects.Objective We explored the effect of SenA on IL-1β ...
Minglei Shao +4 more
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Prevention and combating measures against doping in the Republic of Moldova
One Health & Risk Management, 2023 Introduction. Anabolic androgenic steroids are synthetic hormones designed to enhance the body's ability to produce muscle tissue. Despite their therapeutic effects, these steroids come with a range of side effects, which vary based on each user's ...
Artiom JUCOV +2 more
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Modulation of Perlecan Protein towards Chondrocyte Secretion Factors at the Articular Cartilage in Hyperglycemic Animal Model [PDF]
Journal of Pure and Applied Chemistry Research, 2019 High carbohydrate influences the cartilage microcellular environment and chondrocytes. Perlecan (HSPG2) conducts an essential role as chondrocytes mechano-transducer and chondrocytes secretion factors. This research aims to fulfill the research gap about
Ibrahim Njoto +5 more
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, 2021 The use of image- and performance-enhancing drugs particularly anabolic-androgenic steroids (AAS) is not a new phenomenon. AAS use is not limited to athletes, with mainstream populations using these drugs for aesthetic purposes.
Amanda Atkinson (5494721) +4 more
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, 2010 The striking clinical benefits of intermittent parathyroid hormone in osteoporosis have begun a new era of skeletal anabolic agents. Recombinant human parathyroid hormone (rhPTH) (1–34) is the first US Food and Drug Administration–approved anabolic ...
Stuart L. Silverman +3 more
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