Results 31 to 40 of about 167,379 (210)
Background: The driving force behind osteoarthritis (OA) pathogenesis is an anabolic-catabolic (a/c) imbalance. Melatonin (MT) is a key player in maintaining a/c stability and mitigates OA pathogenesis, but mechanisms underlying its effects remain poorly
Dewan Md. Sumsuzzman +17 more
doaj +1 more source
Positioning novel biologicals in CKD-mineral and bone disorders [PDF]
Renal osteodystrophy (ROD), the histologic bone lesions of chronic kidney disease (CKD), is now included in a wider syndrome with laboratory abnormalities of mineral metabolism and extra-skeletal calcifications or CKD-mineral and bone disorders (CKD-MBD),
Covic, Adrian +5 more
core +1 more source
Effect of High Potency Growth Implants on Average Daily Gain of Grass-Fattened Steers
High potency growth promoter implants (HGPs) are widely used under feedlot conditions but there are few reports under grazing conditions. The study’s goal was to assess the effect of HGPs on the average daily gain of steers fattened in pastures.
Rodrigo Arias +2 more
doaj +1 more source
The purpose of this study was to evaluate the effects of a competitive soccer season on biomarkers and performance metrics in order to determine the correlation between changes in biomarkers, body composition, and performance outcomes.
Bridget A. McFadden +13 more
doaj +1 more source
Senkyunolide A inhibits the progression of osteoarthritis by inhibiting the NLRP3 signalling pathway
Context Osteoarthritis (OA) is a degenerative disease. Senkyunolide A (SenA) is an important phthalide from Ligusticum chuanxiong Hort (Umbelliferae) with anti-spasmodic and neuroprotective effects.Objective We explored the effect of SenA on IL-1β ...
Minglei Shao +4 more
doaj +1 more source
Prevention and combating measures against doping in the Republic of Moldova
Introduction. Anabolic androgenic steroids are synthetic hormones designed to enhance the body's ability to produce muscle tissue. Despite their therapeutic effects, these steroids come with a range of side effects, which vary based on each user's ...
Artiom JUCOV +2 more
doaj
In osteoarthritis (OA), inhibition of excessively expressed pro-inflammatory cytokines in the OA joint and increasing the anabolism for cartilage regeneration are necessary.
Reihane Ziadlou +6 more
doaj +1 more source
Objective This study examined the effects of short-term betaine supplementation on muscle endurance, plasma lactate, testosterone and cortisol levels, and the testosterone to cortisol (T/C) ratio in response to acute resistance exercise (RE).
Hamid Arazi +4 more
doaj +1 more source
Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages [PDF]
Oxygen is a critical parameter proposed to modulate the functions of chondrocytes ex-vivo as well as in damaged joints. This article investigates the effect of low (more physiological) oxygen percentage on the biosynthetic and catabolic activity of human
Ströbel, Simon +8 more
core +2 more sources
PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases. [PDF]
Metastatic breast cancer (BrCa) is currently incurable despite great improvements in treatment of primary BrCa. The incidence of skeletal metastases in advanced BrCa occurs up to 70%.
Wang, Bin, Yang, Yanmei
core +2 more sources

