Results 101 to 110 of about 3,324,374 (323)
Clinical Pharmacology &Therapeutics, EarlyView.Thiopurine methyltransferase (TPMT) and Nudix hydrolase 15 (NUDT15) are key enzymes that catabolize thiopurines. Decreased or no‐function alleles in TPMT and NUDT15 are associated with reduced or no enzyme activity and predictive of pronounced adverse effects, including severe myelosuppression, that may occur among individuals treated with standard ...
Maud Maillard +18 more
wiley +1 more source
Gene Expression in Hair Follicle Dermal Papilla Cells after Treatment with Stanozolol
Biomarker Insights, 2009 Doping with anabolic agents is a topic in sports where strength is crucial, e.g. sprinting, weight lifting and many more. Testosterone and its functional analogs are the drugs of choice taken as pills, creams, tape or injections to increase muscle mass ...
M. Reiter +3 more
doaj
Investigations Into the Human Metabolism of Trestolone (7α‐Methyl‐19‐Nortestosterone)
Drug Testing and Analysis, EarlyView.As the known metabolites of 7α‐methyl‐19‐nortestosterone (MENT), M1 and M2, suffer from chromatographic issues under routine doping control conditions, the human metabolism of MENT was reinvestigated. From the numerous new metabolites detected, especially, M5 and M10 were identified as the most promising candidates to be implemented into routine ...
Thomas Piper +2 more
wiley +1 more source
Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss
iMetaMed, EarlyView.As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu +6 more
wiley +1 more source
Move beyond free radical theory of aging
iMetaOmics, EarlyView.Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley +1 more source
Toxicological aspects of anabolics in food of animal origin
Croatian Journal of Food Science and Technology, 2011 Because of the profitability of the meat production in the livestock industry there were many cases of abuse of different substances with anabolic effect - stilbenes, stilbene derivatives, their salts and esters, antithyroid agents, natural and synthetic
B. Antolović +4 more
doaj
Anabolic Agents: Adjuncts to Nutrition Support
Nutrition in Clinical Practice, 2004 Anabolic agents as adjuncts to nutrition support therapy have been used to improve malnutrition and establish anabolism. Growth hormone, insulin‐like growth factor, and anabolic steroids have been studied for their potential to reverse the catabolic process and promote anabolism.
openaire +4 more sources
Interdisciplinary Medicine, EarlyView.Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao +12 more
wiley +1 more source
Improving muscle mass: response of muscle metabolism to exercise, nutrition and anabolic agents [PDF]
, 2008 Kevin D. Tipton, Arny A. Ferrando
openalex +1 more source
Journal of Periodontology, EarlyView.Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis +11 more
wiley +1 more source