Results 131 to 140 of about 29,830 (263)

Sequential Versus Step-Therapy Approaches for Osteoporosis Management in Orthopedic Subspecialties. [PDF]

Curr Osteoporos Rep
Salman SG, Phadke R, Burnett J, Walsh J.
europepmc   +1 more source

Denosumab discontinuation and fracture risk: getting the balance right

Internal Medicine Journal, EarlyView.
Abstract Denosumab is a highly effective therapy for osteoporosis. Since its approval by the Therapeutic Goods Administration (TGA) in 2010, use of denosumab has surged across Australia, delivering substantial fracture‐prevention benefits to tens of thousands of patients. However, stopping denosumab may lead to acute loss of bone with an increased risk
Albert S. Kim, Christian M. Girgis
wiley   +1 more source

Anabolics in Cancer Patients: To Use or Not to Use? [PDF]

Endocrinol Metab (Seoul)
Hong AR.
europepmc   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Periodontitis as a Model for Inflammatory Uncoupling of Bone Remodeling

Journal of Periodontal Research, EarlyView.
Periodontitis can be viewed as a state of inflammatory uncoupling of bone remodeling, in which excessive osteoclast‐mediated resorption coexists with impaired bone formation. This review integrates emerging insights from osteoimmunology, osteocyte biology, mechanobiology, aging, and resolution pathways to position periodontitis as an accessible in vivo
Rafael Scaf de Molon, Sotirios Tetradis, Rolando Vernal, Fabio Renato Manzolli Leite, Thomas E. Van Dyke   +4 more
wiley   +1 more source

Sleep in Trans and Non‐Binary Individuals: A Question of Gender?

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep problems are increasingly prevalent in society. One group that is disproportionately affected includes transgender and non‐binary individuals, whose sex assigned at birth does not match their identified gender. This mismatch can lead to gender minority stress and increases the risk of mental disorders.
Lieve Thecla van Egmond, Antonia Wilhelm, Nora Naib Majani, Birgit Derntl   +3 more
wiley   +1 more source

Bone anabolic agents for the treatment of multiple myeloma. [PDF]

Cancer Microenviron, 2011
Vallet S, Raje N.
europepmc   +1 more source

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

Anabolic Steroid-Induced Cholestatic Jaundice in a Young Adult: An Emerging Clinical Challenge Underscoring the Importance of a Thorough Drug History. [PDF]

Cureus
Han MK, Shayo W, Lwin ZT, Aung MT, Cheng C.   +4 more
europepmc   +1 more source

Sequential Anabolic and Antiresorptive Treatment Promotes Medication‐Related Osteonecrosis of the Jaw in Mice

Oral Diseases, EarlyView.
ABSTRACT Objective To investigate the effects of sequential administration of romosozumab and denosumab on post‐extraction socket healing and osteonecrosis development in a murine tooth extraction model. Methods Forty female mice were randomly assigned to four groups: control (Ctrl), romosozumab (Rm), denosumab (Dmab), and sequential romosozumab ...
Seo‐Yeong An, Hae‐Seo Park, Reuben H. Kim, Moon‐Young Kim   +3 more
wiley   +1 more source