Results 151 to 160 of about 29,623 (261)

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

A Comparison Between Bisphosphonates and Teriparatide in the Treatment of Postmenopausal Osteoporosis: A Systematic Review. [PDF]

Cureus
Mann RS, Chopra I, Kilic A, Saxena A, Khan B, Rupanshu R, Chavez Cavalie PS.   +6 more
europepmc   +1 more source

Redox‐regulated signalling of adaptations to contractile activity in skeletal muscle: Implications for age‐related muscle weakness

Experimental Physiology, EarlyView.
Abstract Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). Early research framed ROS as deleterious byproducts of exercise, but subsequent studies have established their roles as signalling molecules involved in mitochondrial biogenesis,
Malcolm J. Jackson
wiley   +1 more source

A Commentary on "Romosozumab Enhances Implant Stability in Glucocorticoid-Induced Osteoporotic Bone: A Rabbit Model Study". [PDF]

Neurospine
Liu B, Lin H.
europepmc   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Anabolic-Androgenic Steroids Revisited: Structural Biology, Receptor Signaling, and Mechanisms of Anabolic-Androgenic Dissociation. [PDF]

Int J Mol Sci
Wiacek M, Zubrzycki IZ.
europepmc   +1 more source

Endocrine and androgenic response to altitude training in professional cyclists

The Journal of Physiology, EarlyView.
Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss, Bastien Krumm, Claes Cubel, Magnus Bak Klaris, Lasse Vestli Baekken, Yvette Dehnes, Jenna Goodrum, Geoff Miller, James Spragg, Martin Faulhaber, Francesco Botrè, Carsten Lundby   +11 more
wiley   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Pro-inflammatory cytokine-driven molecular signaling in skeletal muscle during cancer cachexia. [PDF]

Biochem Soc Trans
Pati B, Nandy N, Bindhani BK, Bal NC.
europepmc   +1 more source

Artificial gravity during prolonged bed rest preserves resting metabolic rate but not muscle function: Evidence from the BRACE study

The Journal of Physiology, EarlyView.
Abstract figure legend This study examined whether supine cycling exercise, with or without artificial gravity, preserves resting metabolic rate (RMR) during 60 days of head‐down tilt bed rest, and whether RMR responses align with integrated multivariate physiological adaptations.
Saul Martin‐Rodriguez, Mirko Mandić, Claire Laurens, Marie‐Pierre Bareille, Rebecca Billette de Villemeur, Rodrigo Fernandez‐Gonzalo, Chantal Simon   +6 more
wiley   +1 more source