Results 221 to 230 of about 3,324,374 (323)

Pharmacological intervention: Challenges and promising outcomes for fat loss and preservation of lean body mass in the treatment of overweight and type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 803-816, February 2026.
Abstract Treatment with GLP‐1 receptor agonists (GLP‐1 RAs) is effective in reducing body weight in individuals with overweight and type 2 diabetes (T2D). However, measurements indicate that a considerable portion of the weight loss derives from fat‐free mass (FFM), including skeletal muscle, which may compromise metabolic health and physical function.
Viktor Aimelet, Jens Juul Holst
wiley   +1 more source

Diabetes management in maternally inherited diabetes and deafness (MIDD): A review and a proposed treatment algorithm

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.
Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry   +2 more
wiley   +1 more source

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 2, Page 197-204, February 2026.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

Associations of physical activity with phase angle in adolescents living with HIV: The moderating and mediating roles of physical fitness

open access: yesPhysiological Reports, Volume 14, Issue 3, February 2026.
The graphical abstract illustrates the association between physical activity levels and cellular health in adolescents living with HIV (ALHIV). Cellular health was assessed using phase angle (PhA), derived from bioelectrical impedance analysis, a marker of cell membrane integrity and body cell mass.
Caio César da Silva Moura Santos   +5 more
wiley   +1 more source

The Efficacy and Safety of Abaloparatide in Osteoporosis: A Systematic Review and Meta-Analysis. [PDF]

open access: yesJ Clin Med
Bonifacio M   +8 more
europepmc   +1 more source

A Bayesian approach to estimate minute ventilation from heart rate during exercise for assessing environmental exposures of females

open access: yesPhysiological Reports, Volume 14, Issue 3, February 2026.
Abstract Estimating minute ventilation (V̇E) is essential for assessing the health impacts of environmental exposures during exercise field‐studies. Predictive equations using heart rate (HR) are commonly used, but overlook exercise intensity domains, and reduced accuracy is shown, particularly for females.
Gustavo Oneda   +7 more
wiley   +1 more source

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