Results 131 to 140 of about 29,332 (238)

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

Drug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum, Shao‐Hsin Hung, Meng‐Tsang Hsieh, Mei‐Chich Hsu, William Chih‐Wei Chang   +4 more
wiley   +1 more source

Simultaneous Detection of Steroid Esters and Multi‐Class Substances in Dried Blood Spots by LC‐HRMS/MS From a Single Spot for Human Doping Control

Drug Testing and Analysis, EarlyView.
A validated LC‐HRMS/MS method enabled, for the first time, the comprehensive detection of steroid esters and multi‐class menu substances from a single dried blood spot. Following extraction, the resulting extract is split into two aliquots, reducing sample consumption and simplifying the analytical workflow.
Panagiotis Sakellariou, Andreas Thomas, Sebastian Marcel Schröder, Jasmin Thelen, Mario Thevis   +4 more
wiley   +1 more source

A Single‐Aliquot Strategy for Simultaneous Carbon Isotope Confirmation of 6‐Oxo‐Androstenedione and Testosterone Misuse in Doping Control

Drug Testing and Analysis, EarlyView.
This method enables simultaneous carbon isotope confirmation of 6‐oxo‐androstenedione and testosterone markers from a single urine aliquot, using bench‐top extraction, two preparative HPLC steps with intermediate acetylation, and GC/C/IRMS analysis. It was fully validated according to WADA requirements, and real samples demonstrated its fitness for ...
Fábio Azamor de Oliveira, Cristiane Abrantes da Silva, Carolina dos Reis Farias, Mariana Trad Rosner da Motta, Thais Reis da Silva, Natasha Veiga Louzada, Monica Costa Padilha, Henrique Marcelo Gualberto Pereira   +7 more
wiley   +1 more source

Potential Contamination Cases in Anti‐Doping: Experiences and Practices of 33 Anti‐Doping Organisations

Drug Testing and Analysis, EarlyView.
Across 33 Anti‐Doping Organisations (ADOs), 85% reported experiencing at least one contamination‐claim case in 2024–2025, but only 36% operate a standardised process for handling such claims. Dietary supplements were the leading alleged contamination source (76% of ADOs), followed by food (42%) and pharmaceutical products, intimate contact, and other ...
Kristian Slíž, Liene Kozlovska, Fredrik Lauritzen   +2 more
wiley   +1 more source

Evidence for the Effectiveness of the Performance Passport Within an Intelligence‐Based Weightlifting Anti‐Doping Programme

Drug Testing and Analysis, EarlyView.
Anti‐doping programmes require efficient testing, as biological testing is costly; the Athlete Performance Passport (APP) uses performance data to identify at‐risk athletes alongside APMU and ABP methods. Since the introduction of the steriodal passport in 2014, the APP outperformed APMU (17%) and ABP steroidal profiles (10%) with 30% detection ...
Gregory Hayward, Jim E. Griffin, Laurentiu C. Hinoveanu, Lorenzo Gaborini, Neil Robinson, James G. Hopker   +5 more
wiley   +1 more source

Implications of proteome allocation constraints for understanding interbacterial antagonism. [PDF]

Microbiology (Reading)
Booth SC.
europepmc   +1 more source

Intra‐Individual Variability of Blood and Urinary Steroid Markers and the Response to Codeine Intake in Healthy Men and Women

Drug Testing and Analysis, EarlyView.
Short‐term codeine administration (1–3 days) caused individual alterations in Athlete Biological Passport steroid markers, including elevated urinary T/E ratios and decreased serum testosterone concentrations below individual thresholds, despite no significant changes at the group level.
Alexander Andersson, Basam Yousif, Anton Pohanka, Annica Börjesson, Mikael Lehtihet, Lena Ekström   +5 more
wiley   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

MicroRNA-15a/16 regulate protein metabolism and are associated with clinical outcomes in pancreatic ductal adenocarcinoma. [PDF]

Physiol Rep
Ryan PJ, Guerra BC, Nghiem PP, Riechman SE, Janini-Gomes M, Fluckey JD.   +5 more
europepmc   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source