Results 121 to 130 of about 29,332 (238)
Biotechnology and Bioengineering, EarlyView.ABSTRACT Maintaining consistent cellular physiology during bioprocess scale‐up or scale‐down is key to developing robust processes. However, the reliability of scale‐down bioreactor systems remains debated. Although the calibration of physiological parameters in mechanistic models across scales has been proposed as a scale‐down strategy, few studies ...
Fabian Schröder‐Kleeberg +8 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li +3 more
wiley +1 more source
Contribution of amino acids and insulin to protein anabolism during meal absorption.
, 1996 The contribution of dietary amino acids and endogenous hyperinsulinemia to prandial protein anabolism still has not been established. To this end, leucine estimates ([1-14C]leucine infusion, plasma α-ketoisocaproic acid [KIC] specific activity [SA] as ...
BOLLI, Geremia Brunetto +7 more
core
Biotechnology and Bioengineering, EarlyView.ABSTRACT A method to select Escherichia coli citrate synthase variants having reduced activity was developed based initially on the increased generation of acid, observed visually by prolonged color change in the pH indicator bromocresol purple. Five hundred fifty‐two potential variants were isolated and each were cultured on glucose as sole carbon ...
Jeffrey K. Dodelin +3 more
wiley +1 more source
BMEMat, EarlyView.The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu +8 more
wiley +1 more source
ChemFoodChem, EarlyView.This research showed that sausage reformulation preserves high essential amino acid and branched‐chain amino acid content, as well as increasing free amino acids (FAA) related to umami flavor and health‐promoting components such as GABA in the products.
Albert Gashi +4 more
wiley +1 more source
The Impact of Glycation on Protein Digestibility
ChemFoodChem, EarlyView.Schematic overview of how protein glycation affects digestibility and downstream nutritional consequences. Glycation‐derived structural modifications reduce protease accessibility, leading to limited hydrolysis and altered peptide generation. These changes decrease amino acid bioavailability and may subsequently contribute to microbiome alterations ...
Lea Hönemann +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Clinical significance of acute kidney injury in idiosyncratic drug‐induced liver injury: a multicentric propensity scores matched study. Evidence about the role of acute kidney injury (AKI) in idiosyncratic drug‐induced liver injury (DILI) is still scarce.
José María Pinazo‐Bandera +15 more
wiley +1 more source
Knockdown of the E3 Ubiquitin ligase UBR5 and its role in skeletal muscle anabolism
, 2020 UBR5 is an E3-ubiquitin-ligase positively associated with anabolism, hypertrophy and recovery from atrophy in skeletal muscle. The precise mechanisms underpinning UBR5's role in the regulation of skeletal muscle mass remains unknown.
Turner, Daniel C. +10 more
core
The Effect of Isocaloric Dairy and Dairy-Free Alternative Beverages on Post-Exercise Anabolism in Active Children [PDF]
Protein-containing beverages, especially those enriched with essential amino acids, generally support greater post-exercise muscle protein synthesis rates than plant-based proteins in adults.
Pourhashemi, Nicki
core +1 more source