Results 161 to 170 of about 24,072 (312)

<i>Mycobacterium tuberculosis</i> growth arrest on propionate at acidic pH is suppressed by mutations in <i>phoPR</i> and pyrazinamide treatment. [PDF]

mBio
Murdoch HM, Dechow SJ, Abdalla BJ, Abramovitch RB.   +3 more
europepmc   +1 more source

High CO ₂ Downregulates Skeletal Muscle Protein Anabolism via AMP-activated Protein Kinase α2–mediated Depressed Ribosomal Biogenesis

, 2019
Tanner C. Korponay, Joseph Balnis, Catherine E. Vincent, Diane V. Singer, Amit Chopra, Alejandro P. Adam, Roman Ginnan, Harold A. Singer, Ariel Jaitovich   +8 more
openalex   +2 more sources

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

Medicine Bulletin, EarlyView.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng, Rui Li, Huan Li, Jun Zhou, Xuanshi Liu, Guilherme Valente, Tatiana de Campos Melo, Sifan Chen, Lei Gu   +8 more
wiley   +1 more source

A causal model of human growth and its estimation using temporally sparse data. [PDF]

R Soc Open Sci
Bunce JA, Fernández CI, Revilla-Minaya C.   +2 more
europepmc   +1 more source

New Technologies Empower Hemophilic Arthropathy Treatment: Focusing on Regenerative Medicine, Molecular Targeting, and Gene Therapy

Medicine Bulletin, EarlyView.
ABSTRACT Hemophilic arthropathy (HA), a major complication of hemophilia, is a chronic osteoarthropathy driven by repeated joint bleeding. Although traditional therapies such as coagulation factor replacement, physical rehabilitation, and surgery can manage symptoms, they cannot fundamentally repair established joint damage or break the pathological ...
Lin Sun, Yingnan Wang, Leyuan Zhao, Liqiang Lu, Fushan Hou, Chuan Yin, Kun Zhang, Yongqiang Hao, Jingke Fu   +8 more
wiley   +1 more source

Isoginkgetin protects chondrocytes and inhibits osteoarthritis through NF-κB and P21 signaling pathway. [PDF]

Mol Med
Xu M, Chen X, Du S, Xu H, Liu C.
europepmc   +1 more source

Hyperinsulinaemia, hyperaminoacidaemia and post-exercise muscle anabolism: the search for the optimal recovery drink [PDF]

, 2006
Anssi H Manninen
openalex   +1 more source

Proteomics of Prostate Cancer Tissue Small Extracellular Vesicles Reveal Alteration of Metabolism

PROTEOMICS, EarlyView.
ABSTRACT Prostate cancer (PCa) is a leading male malignancy worldwide, with metabolic reprogramming being a critical hallmark of its progression. Extracellular vesicles (EVs) derived from tissues directly reflect the tumor microenvironment, offering unique insights into cancer pathophysiology that are unattainable through cell line or biofluid‐derived ...
Lijuan Yu, Ting Ding, Roger Olofsson Bagge, Lei Zheng, Xiaoke Hao   +4 more
wiley   +1 more source

Metabolite to Modifier: Lactate and Lactylation in the Evolution of Tumors. [PDF]

MedComm (2020)
Zhao L, Cui H, Li Y, Ye Y, Shen Z.
europepmc   +1 more source

Glutamine metabolism in osteoprogenitors governs bone mass accrual and PTH-induced bone anabolism

, 2020
Steve Stegen, Sophie Torrekens, Riet Van Looveren, Peter Carmeliet, Geert Carmeliet   +4 more
openalex   +1 more source