Results 181 to 190 of about 29,332 (238)

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Fexofenadine protects against osteoarthritis by targeting Smad2 and STAT1 to enhance anabolism and binding cPLA2 to inhibit catabolism. [PDF]

Cell Death Discov
Liu K, Zhang X, Ning B, Liu R, Wang C, Cheng L, Zheng W, Wei J.   +7 more
europepmc   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Driving forces of the humification process in composting: from a microbial perspective. [PDF]

Appl Environ Microbiol
Wang J, Chen Y, Li H, Li Y, Jiang H, Jiang K, Wang N, He Y, Yi Z, Peng X.   +9 more
europepmc   +1 more source

Oxidative stress‐driven metabolic reprogramming defines two subtypes of cutaneous melanoma

VIEW, EarlyView.
Cutaneous melanoma exhibits substantial molecular heterogeneity, and metabolic reprogramming may contribute to differences in tumor behavior and treatment response. In this study, we integrated multi‐omics data from SKCM cohorts to identify two metabolism‐associated subtypes with distinct oxidative stress profiles, immune microenvironments, prognostic ...
Qikun Gao, Ziyi Liu, Ying Xu
wiley   +1 more source

Correction to "Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway". [PDF]

Oxid Med Cell Longev
europepmc   +1 more source

Cartilage targeted grape skin-derived extracellular vesicles ameliorate osteoarthritis by attenuating chondrocyte senescence. [PDF]

J Nanobiotechnology
Chen W, Niu L, Wu Y, Chen C, Liu H, Song P, Su T, Shang Y, Zhang Y, Li S, Ma Y, Wang P, Cui J, Su J.   +13 more
europepmc   +1 more source

Fecal Glucocorticoid and Androgen Metabolites in Eastern Gray Kangaroos (Macropus giganteus) Following Environmental Relocation

Zoo Biology, EarlyView.
Fecal glucocorticoid (GCM) and androgen metabolite (AM) concentrations were monitored for 3 months following the relocation of three eastern gray kangaroos (Macropus giganteus) between zoological facilities. Both metabolites showed high concentrations during the early postrelocation period, followed by a rapid decline and stabilization, suggesting ...
Laura Menchetti, Rupert Palme, Livio Galosi, Giacomo Rossi, Elena Fraticelli, Gaia Andrea Bevinetto, Gioia Gaiot, Renato Piccinini, Raffaello Gambi, Matteo Cerquetella   +9 more
wiley   +1 more source

A Nomogram Incorporating Sarcopenia and Nutritional Indicators for Mortality Prediction in HBV-Related Acute-Chronic Liver Failure. [PDF]

Healthcare (Basel)
Yuan J, Peng W, Jiang C, Liu H, Wang S, Jiang Y, Tan B, Fu L, Peng S.   +8 more
europepmc   +1 more source

Life history attributes influencing metabolic variation in an estuarine fish

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Considering that energy availability and oxygen transport potential are limited in supplying metabolic requirements, all animals face trade‐offs between competing metabolic demands.
Elizabeth C. Hoots, Luis L. Kuchenmüller, Michael R. Skeeles, Timothy D. Clark   +3 more
wiley   +1 more source