Results 201 to 210 of about 29,332 (238)

Contact Activation Is Alleviated by Testosterone Replacement Therapy in Klinefelter Syndrome: Evidence of Hormonal and Metabolic Modulation

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang, Claus H. Gravholt, Anne Skakkebæk, Anna‐Marie Bloch Münster, Yaseelan Palarasah   +4 more
wiley   +1 more source

Kampo medicine as a nutrition-relevant multi-target intervention for sarcopenia: implications for appetite, mitochondrial function, and the frailty-sarcopenia-cachexia continuum. [PDF]

Front Nutr
Kurokawa T, Kurokawa T.
europepmc   +1 more source

Associations Between Sperm DNA Fragmentation and Lifestyle Factors

Andrology, EarlyView.
ABSTRACT Background Sperm DNA fragmentation index (DFI) has been proposed as a supplementary biomarker to traditional semen parameters in the evaluation of male infertility. However, its determinants and clinical relevance remain unclear, particularly regarding modifiable lifestyle factors.
Lana Haval Mairof Adams, Lærke Priskorn, Joan‐Carles Arce, Heidi Aasted, Elisabeth Carlsen, Raphael Burkan Al‐Najaar, Anders Juul, Niels Jørgensen   +7 more
wiley   +1 more source

Mechano-metabolic axis involves mitochondrial responses via BMP/Smad regulatory effect on cyclophilin D. [PDF]

Bone Res
Sautchuk R, Nieves Santana J, Yu C, Awad H, Eliseev RA.   +4 more
europepmc   +1 more source

Bone Health and Aging in Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Klinefelter syndrome (KS) is typically diagnosed in young adults, but advances in prenatal testing have led to its recognition at a much earlier age. Conversely, diagnosis in late adulthood remains uncommon, but still occurs. Independently from the age at diagnosis, KS individuals now receive more accurate and tailored care management than in ...
Filippo Vignali, Daniele Renda Livraghi, Francesco Costantino, Sara De Vincentis, Vincenzo Rochira   +4 more
wiley   +1 more source

Reply to "Mechanical tension and autophagy suppression: Unmasking the confounders in ICU muscle preservation strategies". [PDF]

JPEN J Parenter Enteral Nutr
Veldsman L, Richards GA, Nel D, Kohn TA, Blaauw R.   +4 more
europepmc   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

ATG4B is required for mTORC1-mediated anabolic activity and is associated with clinical outcomes in non-small cell lung cancer. [PDF]

FEBS Open Bio
Ryan PJ, Guerra BC, Uranga S, Cardin JM, Riechman SE, Gomes MJ, Fluckey JD.   +6 more
europepmc   +1 more source

Marginal Changes in Semen Quality Over Three Decades (1996‒2022) Among 8320 Men in the Danish Young Men Study (DYMS): Cohort Profile and Trends

Andrology, EarlyView.
ABSTRACT Background Since the 1990s, declining sperm counts and increasing testicular cancer rates have raised worldwide concern about male reproductive health, including in Denmark. This prompted a prospective population‐based study with annual surveillance of semen quality.
Lærke Priskorn, Cille Baslund‐Storch, Laura S. Hansen, Astrid L. Beck, Ann H. Hansen, Stine A. Holmboe, Loa Nordkap, Anne Kirstine Bang, Rune Lindahl‐Jacobsen, Christine Dalgård, Anna‐Maria Andersson, Tina K. Jensen, Anders Juul, Niels Jørgensen   +13 more
wiley   +1 more source

Piezo1 Activation Rescues Anabolic Response to Mechanical Loading in Aged Bone via Connexin 43 Hemichannels. [PDF]

Aging Cell
Zhao D, Fu J, Liu H, Liang S, Song M, Zhang A, Wang DE, Guo Q, Zhang Y, Wu J, Xu H.   +10 more
europepmc   +1 more source