The John J. Larkin, Jr. Memorial Grant in aid for Medical Research Established by the Saint Luke Guild of Catholic Physicians of Boston [PDF]
Kane, Charles A.
core +1 more source
Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li +5 more
wiley +1 more source
A causal model of human growth and its estimation using temporally sparse data. [PDF]
Bunce JA +2 more
europepmc +1 more source
Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu +7 more
wiley +1 more source
Nutritional strategies against skeletal muscle wasting in cancer-associated cachexia: the role of β-hydroxybutyrate and polyunsaturated fatty acids. [PDF]
Hay B +6 more
europepmc +1 more source
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang +6 more
wiley +1 more source
Molecular Mechanisms and Nutritional Modulation in Sarcopenia: A Narrative Review. [PDF]
Chin HS +6 more
europepmc +1 more source
Juvenile Procambarus clarkii exposed to noise exhibited behavioral changes, shifts in enzymatic activity, and altered expression of stress and immune genes. The findings highlight the sensitivity of invertebrate juveniles to anthropogenic acoustic pollution.
Maria Ceraulo +8 more
wiley +1 more source
NsPEFs-enriched ADSCs-EVs alleviate osteoarthritis via RSPO3-mediated dual pro-chondrogenic and pro-M2 macrophage properties. [PDF]
Wang Y +15 more
europepmc +1 more source
What anabolic–androgenic steroids reveal about the limits of current harm reduction models
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski +2 more
wiley +1 more source

