Results 21 to 30 of about 42,863 (306)

Mediators and Patterns of Muscle Loss in Chronic Systemic Inflammation

Frontiers in Physiology, 2018
Besides its primary function in locomotion, skeletal muscle (SKM), which represents up to half of human's weight, also plays a fundamental homeostatic role.
Sandra Pérez-Baos, Iván Prieto-Potin, Jorge A. Román-Blas, Olga Sánchez-Pernaute, Raquel Largo, Gabriel Herrero-Beaumont   +5 more
doaj   +1 more source

Cancer Cachexia Induces Preferential Skeletal Muscle Myosin Loss When Combined With Denervation

Frontiers in Physiology, 2020
Patients with cancer cachexia (CCX) suffer from muscle wasting, which is often but not always accompanied by selective loss of myosin. Here we examined the effects of CCX on muscle mass and myosin heavy chain (MyHC) expression in denervated (DEN) muscles,
Takashi Yamada, Yuki Ashida, Daisuke Tatebayashi, Masami Abe, Koichi Himori   +4 more
doaj   +1 more source

Metabolism in the tumor cell and beyond

Molecular Oncology, 2023
The process of cellular transformation encompasses the acquisition of key and distinctive features, commonly known as hallmarks of cancer. These hallmarks are supported by tumor‐intrinsic molecular alterations, as well as changes in the microenvironment.
Arkaitz Carracedo
doaj   +1 more source

Recent advances of γ-aminobutyric acid: Physiological and immunity function, enrichment, and metabolic pathway

Frontiers in Nutrition, 2022
γ-aminobutyric acid (GABA) is a non-protein amino acid which naturally and widely occurs in animals, plants, and microorganisms. As the chief inhibitory neurotransmitter in the central nervous system of mammals, it has become a popular dietary supplement
Zhou Heli, Chen Hongyu, Bao Dapeng, Bao Dapeng, Tan Yee Shin, Zhong Yejun, Zhang Xi, Wu Yingying   +7 more
doaj   +1 more source

Testosterone treatment in chronic heart failure. Review of literature and future perspectives

Monaldi Archives for Chest Disease, 2018
Mounting evidence suggests that hormonal deficiencies (HD) have an important role in chronic heart failure (CHF). In particular, androgen depletion is common in men with CHF and is associated with increased morbidity and mortality. This review summarizes
Roberta D'Assante, Lucrezia Piccioli, Pietro Valente, Francesca M. Stagnaro, Alessandra Schiavo, Anna Lombardi, Veronica Panicara, Michele Arcopinto, Giuseppe Vitale, Filippo M. Sarullo, Francesco Giallauria, Alberto M. Marra, Andrea Salzano   +12 more
doaj   +1 more source

EFFECT OF LEVELS OF ANIMAL DIETARY PROTEIN AND PROBIOTIC ADDITIVES (SACCHAROMYCES CEREVISIAE AND BACILLUS SUBTILIS) ON INSULIN, TSH AND GROWTH HORMON OF AWASSI SHEEP

Al-Qadisiyah Journal For Agriculture Sciences, 2020
To maintain the body on its metabolic activities, including catabolic and anabolic processes, it needs tools. Insulin, thyroxine, growth hormone and other hormones are considered the tools that contribute to regulate metabolism in living organism.
A. F. Al-Abedi, A. A. Saeed, K. S. Al-Huosyney   +2 more
doaj   +1 more source

A Fenchone Derivative Effectively Abrogates Joint Damage Following Post-Traumatic Osteoarthritis in Lewis Rats

Cells, 2022
Background: In a previous report, we have identified the cannabinoid receptor 2 (CB2) agonist HU308 to possess a beneficial effect in preventing age and trauma-induced osteoarthritis (OA) in mice. The effects of HU308 were largely related to the capacity
Idan Carmon, Reem Smoum, Eli Farhat, Eli Reich, Leonid Kandel, Zhannah Yekhtin, Ruth Gallily, Raphael Mechoulam, Mona Dvir-Ginzberg   +8 more
doaj   +1 more source

Integrative concept of homeostasis: translating physiology into medicine [PDF]

, 2011
To truly understand living systems they must be viewed as a whole. In order to achieve this and to come to some law to which living systems obey, data obtained on cells, tissues and organs should be integrated.
Ivan Spasojevic, Ivan Spasojevic
core   +3 more sources

Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species

Journal of Lipid Research, 2022
Anabolic metabolism of carbon in mammals is mediated via the one- and two-carbon carriers S-adenosyl methionine and acetyl-coenzyme A. In contrast, anabolic metabolism of three-carbon units via propionate has not been shown to extensively occur.
Mary T. Doan, Michael D. Neinast, Erika L. Varner, Kenneth C. Bedi, Jr., David Bartee, Helen Jiang, Sophie Trefely, Peining Xu, Jay P. Singh, Cholsoon Jang, J. Eduardo Rame, Donita C. Brady, Jordan L. Meier, Kenneth B. Marguiles, Zoltan Arany, Nathaniel W. Snyder   +15 more
doaj   +1 more source

Time resolved DNA occupancy dynamics during the respiratory oscillation uncover a global reset point in the yeast growth program

Microbial Cell, 2014
The structural dynamics of chromatin have been implicated in the regulation of fundamental eukaryotic processes, such as DNA transcription, replication and repair.
Cornelia Amariei, Rainer Machné, Viktor Stolc, Tomoyoshi Soga, Masaru Tomita, Douglas B. Murray   +5 more
doaj   +1 more source