Results 101 to 110 of about 101,638 (296)

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Differences in oxygen uptake but equivalent energy expenditure between a brief bout of cycling and running

Nutrition & Metabolism, 2006
Background We examined aerobic and anaerobic exercise energy expenditure and excess post-exercise oxygen consumption (EPOC) between a 250 Watt, 1-minute bout of cycling and uphill treadmill running.
Bunker Michael P, Chason Jeffrey D, Littlefield Nathanael D, Scott Christopher B, Asselin Elizabeth M   +4 more
doaj   +1 more source

Optimal Pacing for Running 400 m and 800 m Track Races

, 2012
Physicists seeking to understand complex biological systems often find it rewarding to create simple "toy models" that reproduce system behavior. Here a toy model is used to understand a puzzling phenomenon from the sport of track and field.
Baumann W., Gajer B., Hanon C., Hirvonen J., Hultman E., James Reardon, Matrahazi Imre, Sage A., Sahlin K., Čoh M.   +9 more
core   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Interval Running Exercise Reduces Running TIME of 800 Meters Dash Without Causing Increased Level of Sgot – Sgpt in Male Students of the Faculty of Sports Sciences, Manado State University [PDF]

, 2009
The effort to gain best achievement in sports by means of exercise has twodilemmatic sides, both for the coaches and sport promoters. On one side, exercise shouldbe done intensely and maximally, but on the other side, it is a known fact that excessiveand
Galatang, A. (Alprodit), Ngurah Nala, I Gusti, Pangkahila, J. A. (Jahja), Tirtayasa, K. (Ketut)   +3 more
core  

Pneumonia Caused by Klebsiella spp. in 46 Horses. [PDF]

, 2015
BackgroundKlebsiella spp. are implicated as a common cause of bacterial pneumonia in horses, but few reports describe clinical presentation and disease progression.Hypothesis/objectivesTo describe the signalment, clinicopathologic data, radiographic and ...
Aleman, M, Byrne, BA, Estell, KE, Kass, PH, Kozikowski, T, Reilly, CM, Swain, EA, Young, A   +7 more
core   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

A Comparison of Two Commercial Swim Bench Ergometers in Determining Maximal Aerobic Power and Correlation to a Paddle Test in a Recreational Surfing Cohort [PDF]

, 2019
The recent addition of surfing to the Tokyo 2020 Olympic Games has fueled a surge in commercial and research interest in understanding the physiological demands of the sport.
Bertacchini, Linley, Canetti, Elisa, Climstein, Mike, Furness, James, Hicklen, Lisa, Monaghan, Dane   +5 more
core   +1 more source

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, Volume 13, Issue 31, 4 June 2026.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Acute effects of pre-exercise voluntary hypocapnic hyperventilation on exercise performance and metabolic responses during high-intensity exercise

Journal of Physical Fitness and Sports Medicine
High-intensity exercise induces the accumulation of hydrogen ions, resulting in a decrease in plasma and muscle pH (i.e., metabolic acidosis), a key mechanism contributing to fatigue. Alleviating metabolic acidosis is crucial for improving high-intensity
Kohei Dobashi, Akira Katagiri, Takeshi Nishiyasu   +2 more
doaj   +1 more source