Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics [PDF]
Cell Reports, 2019 Summary: The cellular responses induced by mitochondrial dysfunction remain elusive. Intrigued by the lack of almost any glomerular phenotype in patients with profound renal ischemia, we comprehensively investigated the primary sources of energy of ...
Paul T. Brinkkoetter +21 more
doaj +4 more sources
LncRNA-DANCR Interferes With miR-125b-5p/HK2 Axis to Desensitize Colon Cancer Cells to Cisplatin vis Activating Anaerobic Glycolysis. [PDF]
Front Oncol, 2020 Colon cancer is one of the most prevalent malignancies that lead to high occurrence of cancer-related deaths. Currently, chemotherapies and radiotherapies remain the primary treatments for advanced colon cancer.
Shi H +5 more
europepmc +4 more sources
Cancer Biology & Medicine, 2017 Uncoupling protein 1 (UCP1) is a proton transporter/channel residing on the inner mitochondrial membrane and is involved in cellular heat production. Using immunohistochemistry, we investigated the expression of UCP1 and UCP3 in a series of 98 patients ...
Alexandra Giatromanolaki +5 more
doaj +4 more sources
Enhancement of anaerobic glycolysis - a role of PGC-1α4 in resistance exercise. [PDF]
Nat Commun, 2022 Koh JH +8 more
europepmc +4 more sources
Low-dose YC-1 combined with glucose and insulin selectively induces apoptosis in hypoxic gastric carcinoma cells by inhibiting anaerobic glycolysis. [PDF]
Sci Rep, 2017 Wakiyama K +7 more
europepmc +4 more sources
Dexmedetomidine alleviated neuropathic pain in dorsal root ganglion neurons by inhibition of anaerobic glycolysis activity and enhancement of ROS tolerance. [PDF]
Biosci Rep, 2020 Neuropathic pain is a kind of chronic pain that is triggered or caused primarily by damage to the nervous system and neurological dysfunction. It’s known that dexmedetomidine is a new type of highly selective alpha2-adrenoceptor agonist with sedation ...
Liu P +7 more
europepmc +2 more sources
Upregulation of Krebs cycle and anaerobic glycolysis activity early after onset of liver ischemia. [PDF]
PLoS One, 2018 The liver is a highly vascularized organ receiving a dual input of oxygenated blood from the hepatic artery and portal vein. The impact of decreased blood flow on glucose metabolism and how hepatocytes could adapt to this restrictive environment are ...
Chan TS +9 more
europepmc +2 more sources
Untargeted Metabolomics Reveals Anaerobic Glycolysis as a Novel Target of the Hepatotoxic Antidepressant Nefazodone [PDF]
Journal of Pharmacology and Experimental Therapeutics, 2020 Mitochondrial damage is considered a hallmark of drug-induced liver injury (DILI). However, despite the common molecular etiology, the evolution of the injury is usually unpredictable, with some cases that are mild and reversible upon discontinuation of ...
Evelin Krajnc +6 more
semanticscholar +2 more sources
PLoS ONE, 2023 Candida albicans can cause two major types of infections: superficial infection and systemic candidiasis. C. albicans infects diverse host niches, owing to a wide range of virulence factors and attributes, such as morphological transitions and phenotypic
Ken Okabayashi +7 more
doaj +4 more sources
ANAEROBIC GLYCOLYSIS IN AMPHIBIAN DEVELOPMENT. HOMOGENATES
The Biological Bulletin, 1964 1. Freshly prepared homogenates of R. pipiens embryos contain considerable amounts of lactic acid, aerobically produced from an unknown source. The amount present is an increasing function of the age of the embryos from which the homogenates are made.2. In the presence of suitable exogenous substrates, anaerobic homogenates of R.
Mary Ann Parker +2 more
openaire +5 more sources