Results 1 to 10 of about 38,740 (241)

Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics

Cell Reports, 2019
Summary: The cellular responses induced by mitochondrial dysfunction remain elusive. Intrigued by the lack of almost any glomerular phenotype in patients with profound renal ischemia, we comprehensively investigated the primary sources of energy of ...
Paul T. Brinkkoetter, Tillmann Bork, Sarah Salou, Wei Liang, Athanasia Mizi, Cem Özel, Sybille Koehler, H. Henning Hagmann, Christina Ising, Alexander Kuczkowski, Svenia Schnyder, Ahmed Abed, Bernhard Schermer, Thomas Benzing, Oliver Kretz, Victor G. Puelles, Simon Lagies, Manuel Schlimpert, Bernd Kammerer, Christoph Handschin, Christoph Schell, Tobias B. Huber   +21 more
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NOVEL CORONAVIRUS VULNERABILITY: METABOLIC DERANGEMENTS AND ALTERED DEHYDROGENASE ENZYME ACTIVITIES ARE CENTRAL TO THE VIRUS PATHOGENESIS IN HUMAN, BAT AND OTHER ANIMALS [PDF]

Exploratory Animal and Medical Research, 2021
The ongoing pandemic of novel coronavirus disease (COVID-19) has killed millions across the globe. This paper hypothesizes anaerobic glycolysis and dehydrogenase enzymes as the focal points of SARS-CoV-2 pathogenesis that ensure virus survival and ...
Sanjib Kumar Manna
doaj   +1 more source

Changes in the mRNA expression of glycolysis-related enzymes of Candida albicans during inhibition of intramitochondrial catabolism under anaerobic condition

PLoS ONE, 2023
Candida albicans can cause two major types of infections: superficial infection and systemic candidiasis. C. albicans infects diverse host niches, owing to a wide range of virulence factors and attributes, such as morphological transitions and phenotypic
Ken Okabayashi, Hitomi Ogawa, Yuto Hirai, Kureha Nagata, Yukiko Sato, Takanori Narita, Kazuo Satoh, Koichi Makimura   +7 more
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Transcriptome analysis of anaerobic glycolysis effects on Jurkat T cell proliferation [PDF]

Central European Journal of Immunology
Ziyu Wang, Hongyang Wang, Qinghai Wang, Tao Huang, Chen Guo, Jianlei Ji, Meijie Su, Weijia Xu, Yanwei Cao, Zhen Dong   +9 more
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Effect of anhydrous betaine and hydrochloride betaine on growth performance, meat quality, postmortem glycolysis, and antioxidant capacity of broilers

Poultry Science, 2022
: This study was conducted to investigate the effect of anhydrous betaine and hydrochloride betaine on growth performance, meat quality, relaxometry, postmortem glycolysis, and antioxidant capacity of partridge shank broiler chickens.
R. Chen, M. Yang, Y.D. Song, R.X. Wang, C. Wen, Q. Liu, Y.M. Zhou, S. Zhuang   +7 more
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Glycolytic activity is required for the onset of neural plate folding during neural tube closure in mouse embryos

Frontiers in Cell and Developmental Biology, 2023
Physiological hypoxia is critical for placental mammalian development. However, the underlying mechanisms by which hypoxia regulates embryonic development remain unclear.
Daisuke Sakai, Yuki Murakami, Daichi Shigeta, Mitsuhiro Tomosugi, Hiromi Sakata-Haga, Toshihisa Hatta, Hiroki Shoji   +6 more
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Metabolic Switch and Cytotoxic Effect of Metformin on Burkitt Lymphoma

Frontiers in Oncology, 2021
Altered cellular energetic metabolism has recently emerged as important feature of neoplastic cells. Indeed, interfering with cancer cell metabolism might represent a suitable therapeutic strategy.
Irene Bagaloni, Axel Visani, Sara Biagiotti, Annamaria Ruzzo, Mohsen Navari, Mohsen Navari, Mohsen Navari, Maryam Etebari, Maryam Etebari, Lucia Mundo, Lucia Mundo, Massimo Granai, Massimo Granai, Stefano Lazzi, Alessandro Isidori, Federica Loscocco, Jiejin Li, Lorenzo Leoncini, Giuseppe Visani, Mauro Magnani, Pier Paolo Piccaluga, Pier Paolo Piccaluga, Pier Paolo Piccaluga, Pier Paolo Piccaluga   +23 more
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Survivin promotes a glycolytic switch in CD4+ T cells by suppressing the transcription of PFKFB3 in rheumatoid arthritis

iScience, 2022
Summary: In this study, we explore the role of nuclear survivin in maintaining the effector phenotype of IFNγ-producing T cells acting through the transcriptional control of glucose utilization.
Malin C. Erlandsson, Karin M.E. Andersson, Nina Y. Oparina, Venkataragavan Chandrasekaran, Tibor Saghy, Anastasios Damdimopoulos, Maria-Jose Garcia-Bonete, Zakaria Einbeigi, Sofia T. Silfverswärd, Marcela Pekna, Gergely Katona, Maria I. Bokarewa   +11 more
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Synaptic modifications transform neural networks to function without oxygen

BMC Biology, 2023
Background Neural circuit function is highly sensitive to energetic limitations. Much like mammals, brain activity in American bullfrogs quickly fails in hypoxia.
Lara Amaral-Silva, Joseph M. Santin
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Sugarcane mosaic virus orchestrates the lactate fermentation pathway to support its successful infection

Frontiers in Plant Science, 2023
Viruses often establish their own infection by altering host metabolism. How viruses co-opt plant metabolism to support their successful infection remains an open question.
Tong Jiang, Tong Jiang, Kaitong Du, Pei Wang, Xinhai Wang, Lianyi Zang, Dezhi Peng, Xi Chen, Geng Sun, Hao Zhang, Zaifeng Fan, Zhiyan Cao, Tao Zhou   +12 more
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