Results 171 to 180 of about 341,458 (322)
Characterization of the in vitro quality parameters of cold‐stored platelets containing aggregates
Vox Sanguinis, EarlyView.Abstract Background and Objectives Cold‐stored platelets (CSP) are being used more widely for the treatment of bleeding because of their longer shelf life. However, storage at low temperatures can induce the formation of platelet aggregates. We aimed to study the impact of aggregate formation on platelet quality and function.
Lacey Johnson +3 more
wiley +1 more source
Veterinary Surgery, EarlyView.Abstract Objective To compare the utility of a saline‐based modified del Nido (mDN) cardioplegia solution with a conventional institutional technique (multidose St. Thomas blood cardioplegia) for mitral valve repair (MVR) in dogs. Study design Prospective, randomized, open‐label trial.
Kentaro Kurogochi +7 more
wiley +1 more source
Apnoea as a novel method to improve exercise performance: A current state of the literature
Experimental Physiology, EarlyView.Abstract Acute breath‐holding (apnoea) induces a spleen contraction leading to a transient increase in haemoglobin concentration. Additionally, the apnoea‐induced hypoxia has been shown to lead to an increase in erythropoietin concentration up to 5 h after acute breath‐holding, suggesting long‐term haemoglobin enhancement.
Janne Bouten +4 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an exercise intervention on the metabolome of T2DM participants, fasting and in response to an oral glucose ...
Maartje Cox +8 more
wiley +1 more source
Adaptations to hypoxia in the vertebrate retina
The Journal of Physiology, EarlyView.Abstract figure legend Most animals, including mammals, are susceptible to the damaging effects of hypoxia or ischaemia, where the result is neuronal cell death in the brain. By contrast, some neurons of the mammalian retina are less sensitive to hypoxia. In both brain and retina, neurons may survive if first preconditioned with ischaemia.
Michael G. Jonz
wiley +1 more source
Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
The Journal of Physiology, EarlyView.Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich +5 more
wiley +1 more source
Influence of opioids on activity of enzymes in kidneys at no-induced apoptosis
RUDN Journal of Medicine, 2009 The influence of dalarginum on activity of enzymes SOD and LDG in cells of a kidney is investigated at the production of nitric oxide. In experiment the infringement of enzymes activity is installed: the activation of anaerobic glycolysis and oppression ...
I A Komarevtseva +2 more
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