Results 181 to 190 of about 71,019 (261)

Alterations in Gut Microbiota and Metabolic Profiles in Relapsed or Refractory Lymphoma

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Metabolomic volcano‐heatmap reveals seven upregulated metabolites in relapsed/refractory lymphoma, underscoring gut metabolic reprogramming as a potential therapeutic target. ABSTRACT To identify potential therapeutic strategies for relapsed or refractory lymphoma (R/RL) by examining differences in gut microbiota composition and metabolic profiles ...
Yu‐Ying Guo, Kang‐Jing Xue, Liao Wang, Gang‐Gang Wang, Ting‐Ting Zhang, Shu‐Ling Hou   +5 more
wiley   +1 more source

Organ‐on‐a‐Chip Technology and Global Multi‐Omics: Current Applications and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Comparative analysis of multiple cell culture models. The 3D microfluidic organ‐on‐a‐chip, which is superior to the existing models in multiple aspects, can be more conducive to new studies and discoveries related to human beings. Created with BioRender (www.biorender.com).
Xuxia Cao, Congmin Xia, Caifeng Li, Shiwen Deng, Junxian Cao, Hongjun Yang, Shaoping Wang, Peng Chen   +7 more
wiley   +1 more source

Low-dose YC-1 combined with glucose and insulin selectively induces apoptosis in hypoxic gastric carcinoma cells by inhibiting anaerobic glycolysis. [PDF]

Sci Rep, 2017
Wakiyama K, Kitajima Y, Tanaka T, Kaneki M, Yanagihara K, Aishima S, Nakamura J, Noshiro H.   +7 more
europepmc   +1 more source

An Injectable Nanocomposite Hydrogel for Efficient Triple Cancer Starvation Therapy In Vivo

Nano Select, Volume 7, Issue 2, February 2026.
In recent years, starvation therapy has gradually become an attractive cancer treatment method. However, single starvation therapy has gradually been replaced by synergistic therapy due to the unsatisfactory therapeutic efficacy. Herein, a novel therapeutic approach—triple starvation therapy—is illustrated by an injectable nanocomposite hydrogel ...
Yang Luo, Miao Cai, Yu Zhou, Liping He, E Liu, Huaxin Zhang   +5 more
wiley   +1 more source

Selective and Tunable Routes for Glucose to Fructose Conversion Using MgCl2 Catalysis and Comparison to Other Metal Ions

ChemistryOpen, Volume 15, Issue 2, February 2026.
MgCl2 is a cheap catalyst for glucose to fructose conversion in water with excellent selectivity if competing pathways leading to CC bond breakage avoided by control of pH and oxygen and use of mild temperatures. Both a stereoselective 1,2‐hydride shift and isomerization via an enediol intermediate contribute to the isomerization.
Ramesh Maragani, Sebastian Meier
wiley   +1 more source

Carboxydotrophic Acetogenesis in Alkaline Conditions Results in Transient Formate Production by the Halo‐Alkaliphilic Acetogen Haloacetibacter carboxydivorans Gen. Nov. sp. Nov

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This work presents the physiological exploration of the halo‐alkaliphilic, carboxydotrophic acetogen bacterium MD4. In contrast to well‐characterised neutrophilic and slightly acidophilic acetogenic carboxydotrophs, this work shows an important role for formate production, instead of ethanol, as a redox exhaust mechanism in alkaline conditions ...
Martijn Diender, Isabelle M. Keijsers, Anastasia Galani, Timo van Roosmalen, Alfons J. M. Stams, Diana Z. Sousa   +5 more
wiley   +1 more source

Selection for Postponed Senescence in Drosophila melanogaster Reveals Distinct Metabolic Aging Trajectories Modifiable by the Angiotensin‐Converting Enzyme Inhibitor Lisinopril

Aging Cell, Volume 25, Issue 2, February 2026.
Assessment of oxygen consumption rates in young, middle‐aged, and old flies from the Drosophila B lines and long‐lived O lines revealed a significant increase in metabolic rate with aging only in B flies. Lisinopril prevented the age‐related rise in metabolic rate in B female flies.
Denise Vecchié, Robert R. H. Anholt, Trudy F. C. Mackay, Maria De Luca   +3 more
wiley   +1 more source

Burning fast & slow: a review of the differential metabolic routes of brown adipose tissue activity during cold exposure and their implications for populational variation. [PDF]

Lipids Health Dis
Ocobock C, Niclou A, Stenbäck V, McElreavy D.   +3 more
europepmc   +1 more source

LAG‐3+ Regulatory T Cells Suppress Effector Function of T Cells and Allow Their Proliferation Into Regulatory T Cells

Immunology, Volume 177, Issue 2, Page 317-328, February 2026.
LAG‐3+ regulatory T cells suppress the effector but not the proliferative response of naïve cognate antigen‐specific CD4+ T cells in vivo. The suppressed T cells display upregulation of immune checkpoints and downregulation of pro‐inflammatory pathways with enhanced TCR signaling and reduced oxidative metabolism.
Avijit Dutta, Shi‐Chuen Miaw, Tse‐Ching Chen, Chia‐Shiang Chang, Yu‐Lin Huang, Yung‐Chang Lin, Chun‐Yen Lin, Ching‐Tai Huang   +7 more
wiley   +1 more source

Glycolysis in polycystic ovary syndrome: pathogenesis and treatment. [PDF]

J Ovarian Res
Xing L, Shi M, Wang Z, Gao H, Li D, Guo R, Zhou X, Chen Y, Xu J, Liang Z, Li T, Zhang K, Shi H, Wang J, Wang R, Zhao R.   +15 more
europepmc   +1 more source