Results 181 to 190 of about 350,338 (294)

LAG‐3+ Regulatory T Cells Suppress Effector Function of T Cells and Allow Their Proliferation Into Regulatory T Cells

Immunology, EarlyView.
LAG‐3+ regulatory T cells suppress the effector but not the proliferative response of naïve cognate antigen‐specific CD4+ T cells in vivo. The suppressed T cells display upregulation of immune checkpoints and downregulation of pro‐inflammatory pathways with enhanced TCR signaling and reduced oxidative metabolism.
Avijit Dutta, Shi‐Chuen Miaw, Tse‐Ching Chen, Chia‐Shiang Chang, Yu‐Lin Huang, Yung‐Chang Lin, Chun‐Yen Lin, Ching‐Tai Huang   +7 more
wiley   +1 more source

The key mechanisms associated with the survival of Gulf toadfish, Opsanus beta, when in severe hypoxia

Journal of Fish Biology, EarlyView.
Abstract Florida's shallow seagrass beds experience daily diurnal fluctuations in environmental oxygen, leading to hypoxic episodes (PO2 < 2 mg L−1, ~6 kPa) that have increased in frequency and intensity in recent decades. The native Gulf toadfish (Opsanus beta) have been shown to employ a suite of adaptive cardiovascular, ventilatory and metabolic ...
Anastasiya Plotnikova, Isabelle R. Nelson, Shara Y. Sookhoo, Jacob M. Belkin, Vanessa P. Lima, Ross D. Bronfman Bunch, Athena M. Santomero, Sophia A. Santomero, Emily C. Rodriguez, Jayda K. Rodriguez, Kathleen M. Davis, Amanda J. Kaplan, Lucy M. Schwartz, Vivienne S. Clarke, Henry W. Sage, Ana I. Ruiz Criado, Kennedy T. Diamond, M. Danielle McDonald   +17 more
wiley   +1 more source

The role of opines on the anaerobic glycolysis of molluscs.

, 1990
Minoru Sato
openalex   +2 more sources

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Alkaline pH-Driven Metabolic Plasticity of Lactococcus lactis FM03. [PDF]

Environ Microbiol
Alkaline pH induces a metabolic shift in Lactococcus lactis FM03 from mixed‐acid to homolactic fermentation, driven by proteome‐level constraints in the mixed‐acid branch. This shift reduces biomass yield despite unchanged bioenergetics. Moreover, alkaline pH changes cell morphology and prevents elongation at higher growth rates.
Bendig TAL, Abee T, Boeren S, Smid EJ, van Mastrigt O.   +4 more
europepmc   +2 more sources

Stimulation of glycolysis in anaerobic elongation of pondweed (Potamogeton distinctus) turions [PDF]

, 2002
Takuya Sato
openalex   +1 more source

Whole‐Genome Sequencing and Phenotyping Reveal Specific Adaptations of Lachancea thermotolerans to the Winemaking Environment

Molecular Ecology, EarlyView.
ABSTRACT Adaptation to the environment plays an essential role in yeast evolution as a consequence of selective pressures. Lachancea thermotolerans, a yeast related to fermentation and one of the current trends in wine technology research, has undergone an anthropisation process, leading to a notable genomic and phenomic differentiation.
Javier Vicente, Anne Friedrich, Joseph Schacherer, Kelle Freel, Domingo Marquina, Antonio Santos   +5 more
wiley   +1 more source

The Gfr Uptake System Provides a Context‐Dependent Fitness Advantage to Salmonella Typhimurium SL1344 During the Initial Gut Colonization Phase

Molecular Microbiology, EarlyView.
Diet–microbiota interactions shape colonization resistance. While the microbiota restricts pathogens like Salmonella through nutrient competition, Salmonella can exploit private nutrients such as fructoselysine (FL), abundant in processed foods but inaccessible to most microbes.
Lea Fuchs, Cora Lisbeth Dieterich, Elena Melgarejo Ros, Philipp Keller, Anna Sintsova, Leanid Laganenka, Thomas A. Scott, Christopher Schubert, Shinichi Sunagawa, Julia A. Vorholt, Jörn Piel, Wolf‐Dietrich Hardt, Bidong D. Nguyen   +12 more
wiley   +1 more source

Enhanced O2 availability in platelet concentrates stored for neonatal transfusion is independent of agitation: Evidence from direct oximetry and Fickian diffusion modelling

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Platelet transfusions are essential for mitigating the bleeding risk of neonatal patients with thrombocytopenia. As neonatal patients have a small blood volume, adult therapeutic dose platelet units are split into reduced‐volume storage containers to maximize the use of the donated product and reduce donor exposure ...
Dean Pym, Oleg Grinberg, Amanda J. Davies, Jessica O. Williams, Christine Saunders, Chloë E. George, Philip E. James   +6 more
wiley   +1 more source

Effects of short‐term exercise on plasma metabolic and lipidomic profiles of individuals with type 2 diabetes

Experimental Physiology, EarlyView.
Abstract Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an exercise intervention on the metabolome of T2DM participants, fasting and in response to an oral glucose ...
Maartje Cox, Aaron Raman, Timothy Fairchild, John P. Beilby, Bu B. Yeap, Jeremy K. Nicholson, Julien Wist, Jeremiah Peiffer, Nathan G. Lawler   +8 more
wiley   +1 more source