Results 231 to 240 of about 350,338 (294)

Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential

open access: yesMedComm, Volume 6, Issue 11, November 2025.
This review systematically summarizes dendritic cells (DCs) originating from hematopoietic stem cells, their major subsets (cDC1s, cDC2s, pDCs, moDCs, LCs) and core functions (antigen capture/presentation, adaptive immunity activation, immune tolerance induction, and regulation of innate immune cells).
Fangfang Jin   +7 more
wiley   +1 more source

Fusobacterium nucleatum in Health and Disease

open access: yesMedComm, Volume 6, Issue 11, November 2025.
Fusobacterium nucleatum (Fn), an oral commensal and opportunistic pathogen, primarily colonizes the oral cavity. It contributes to multiple nonmalignant diseases and cancers—especially colorectal cancer—through interaction with the host and other microbes, leading to inflammation, enhanced cellular proliferation, metastatic progression, and immune ...
Xinyi Yang   +3 more
wiley   +1 more source

Stealth Drug Delivery of Mouse Serum Albumin‐Coated Paclitaxel‐Loaded Gelatin Nanoparticles for Targeted Cancer Therapy in Mice

open access: yesNano Select, Volume 6, Issue 11, November 2025.
Our study presents a novel approach to localized cancer therapy by developing mouse serum albumin (MSA)‐coated paclitaxel (PTX)‐loaded gelatin nanoparticles (MSA@PTX‐loaded GNPs) as a stealth drug delivery system. Given the challenges of nanoparticle‐based chemotherapy, including rapid opsonization and limited drug accumulation at tumor sites, our work
Md. Annur Sadman   +10 more
wiley   +1 more source

Dual role of lactate in human health and disease. [PDF]

open access: yesFront Physiol
Kumar S   +4 more
europepmc   +1 more source

Dysregulated mitochondrial energy metabolism drives the progression of mucosal field effects to invasive bladder cancer

open access: yesThe Journal of Pathology, Volume 267, Issue 3, Page 329-346, November 2025.
Abstract Multiplatform mutational and gene expression profiling complemented with proteomic and metabolomic spatial mapping were used on the whole‐organ scale to identify the molecular profile of bladder cancer evolution from field effects. Analysis of the mutational landscape identified three types of mutations, referred to as α, β, and γ.
Sangkyou Lee   +20 more
wiley   +1 more source

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