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The Structural Basis of Babesia orientalis Lactate Dehydrogenase
Glycolytic enzymes play a crucial role in the anaerobic glycolysis of apicomplexan parasites for energy generation. Consequently, they are considered as potential targets for new drug development. Previous studies revealed that lactate dehydrogenase (LDH)
Long Yu+14 more
doaj +1 more source
Glucose availability and sensitivity to anoxia of isolated rat peripheral nerve [PDF]
The contrast between resistance to ischemia and ischemic lesions in peripheral nerves of diabetic patients was explored by in vitro experiments. Isolated and desheathed rat peroneal nerves were incubated in the following solutions with different glucose ...
DYCK P. J.+11 more
core +1 more source
Infections with intestinal nematodes have an equivocal impact: they represent a burden for human health and animal husbandry, but, at the same time, may ameliorate auto-immune diseases due to the immunomodulatory effect of the parasites.
Wjatscheslaw Liublin+9 more
doaj +1 more source
E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells [PDF]
RATIONALE: The majority of current cardiovascular cell therapy trials use bone marrow progenitor cells (BM PCs) and achieve only modest efficacy; the limited potential of these cells to differentiate into endothelial-lineage cells is one of the major ...
Boriboun, Chan+17 more
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ATP and Lactate Quantification
Cells use glucose to generate energy by two different metabolic processes: lactic fermentation and aerobic respiration. In the first common series of reactions, glucose is converted into pyruvate.
Isaline Rowe+2 more
doaj +1 more source
Electron bifurcation mechanism and homoacetogenesis explain products yields in mixed culture anaerobic fermentations [PDF]
Anaerobic fermentation of organic wastes using microbial mixed cultures is a promising avenue to treat residues and obtain added-value products. However, the process has some important limitations that prevented so far any industrial application.
González-Cabaleiro, R.+4 more
core +4 more sources
Glycation Interferes with the Expression of Sialyltransferases in Meningiomas
Meningiomas are the most common non-malignant intracranial tumors and prefer, like most tumors, anaerobic glycolysis for energy production (Warburg effect).
Philipp Selke+6 more
doaj +1 more source
MEASUREMENT OF ANAEROBIC GLYCOLYSIS IN BRAIN AS RELATED TO POLIOMYELITIS [PDF]
Experiments with mouse brain, homogenates show that the anaerobic glycolysis of such preparations can be increased tenfold by addition of appropriate coenzymes and phosphate esters. The previously reported alterations in anaerobic glycolysis during poliomyelitis, as measured with low activity preparations, are believed to be of doubtful value in so far
John M. Reiner+2 more
openaire +3 more sources
A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]
During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core +2 more sources
The anaerobic threshold: 50+ years of controversy
The anaerobic threshold (AT) remains a widely recognized, and contentious, concept in exercise physiology and medicine. As conceived by Karlman Wasserman, the AT coalesced the increase of blood lactate concentration ([La−]), during a progressive exercise
D. Poole+3 more
semanticscholar +1 more source