Results 51 to 60 of about 345,476 (333)

Minimizing acetate formation in E. coli fermentations [PDF]

open access: yes, 2007
Escherichia coli remains the best established production organisms in industrial biotechnology. However, during aerobic fermentation runs at high growth rates, considerable amounts of acetate are accumulated as by-product.
De Maeseneire, Sofie   +3 more
core   +2 more sources

Astrocyte Elevated Gene-1 Mediates Glycolysis and Tumorigenesis in Colorectal Carcinoma Cells via AMPK Signaling

open access: yesMediators of Inflammation, 2014
To investigate the role of AEG-1 in glycolysis and tumorigenesis, we construct myc-AEG-1 expression vector and demonstrate a novel mechanism that AEG-1 may increase the activity of AMPK by Thr172 phosphorylation.
Hong-tao Song   +5 more
doaj   +1 more source

Phosphoproteomic Analysis of Xenopus laevis Reveals Expression and Phosphorylation of Hypoxia-Inducible PFKFB3 during Dehydration

open access: yesiScience, 2020
Summary: Xenopus laevis tolerate dehydration when their environments evaporate during summer months. Protein phosphorylation has previously shown to regulate important adaptations in X. laevis, including the transition to anaerobic metabolism.
Liam J. Hawkins   +4 more
doaj   +1 more source

The Structural Basis of Babesia orientalis Lactate Dehydrogenase

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Glycolytic enzymes play a crucial role in the anaerobic glycolysis of apicomplexan parasites for energy generation. Consequently, they are considered as potential targets for new drug development. Previous studies revealed that lactate dehydrogenase (LDH)
Long Yu   +14 more
doaj   +1 more source

Glycolytic reprograming in Salmonella counters NOX2-mediated dissipation of ΔpH. [PDF]

open access: yes, 2020
The microbial adaptations to the respiratory burst remain poorly understood, and establishing how the NADPH oxidase (NOX2) kills microbes has proven elusive. Here we demonstrate that NOX2 collapses the ΔpH of intracellular Salmonella Typhimurium.
Chakraborty, Sangeeta   +7 more
core  

The Activity of Antioxidant and Anaerobic Glycolysis Enzymes Under Thermal Gradient Exposure in Palearctic Species Lymnaea stagnalis [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2013
The aim of present study was the evaluation of antioxidant (peroxidase, catalase, glutathione S transferase) and anaerobic glycolysis (lactate dehydrogenase) enzymes activity under thermal gradient in Palearctic species Lymnaea stagnalis ...
Vereshchagina К.P.   +8 more
doaj  

hZIP1 Inhibits Progression of Clear Cell Renal Cell Carcinoma by Suppressing NF-kB/HIF-1α Pathway

open access: yesFrontiers in Oncology, 2021
PurposeAccumulating literature has suggested that hZIP1 and HIF-1α play vital roles in the tumor process of clear cell renal cell carcinoma (ccRCC). However, the functional roles of hZIP1 and HIF-1α in ccRCC remain largely unknown.MethodsHIF-1α protein ...
Bo Zhan   +4 more
doaj   +1 more source

MEASUREMENT OF ANAEROBIC GLYCOLYSIS IN BRAIN AS RELATED TO POLIOMYELITIS [PDF]

open access: yesJournal of Experimental Medicine, 1945
Experiments with mouse brain, homogenates show that the anaerobic glycolysis of such preparations can be increased tenfold by addition of appropriate coenzymes and phosphate esters. The previously reported alterations in anaerobic glycolysis during poliomyelitis, as measured with low activity preparations, are believed to be of doubtful value in so far
John M. Reiner   +2 more
openaire   +3 more sources

NAD(P)H fluorescence lifetime imaging of live intestinal nematodes reveals metabolic crosstalk between parasite and host

open access: yesScientific Reports, 2022
Infections with intestinal nematodes have an equivocal impact: they represent a burden for human health and animal husbandry, but, at the same time, may ameliorate auto-immune diseases due to the immunomodulatory effect of the parasites.
Wjatscheslaw Liublin   +9 more
doaj   +1 more source

The anaerobic threshold: 50+ years of controversy

open access: yesJournal of Physiology, 2020
The anaerobic threshold (AT) remains a widely recognized, and contentious, concept in exercise physiology and medicine. As conceived by Karlman Wasserman, the AT coalesced the increase of blood lactate concentration ([La−]), during a progressive exercise
D. Poole   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy