Results 51 to 60 of about 334,223 (370)
ACS Nano, 2017 In this study, we developed a general method to decorate plasmonic gold nanorods (GNRs) with a CD44-targeting functional polymer, containing a hyaluronic acid (HA)-targeting moiety and a small molecule Glut1 inhibitor of diclofenac (DC), to obtain GNR/HA-
Wei‐Hai Chen +7 more
semanticscholar +1 more source
A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]
, 1988 During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core +2 more sources
Adenosine Triphosphate and Carbon Efficient Route to Second Generation Biofuel Isopentanol. [PDF]
, 2020 Climate change necessitates the development of CO2 neutral or negative routes to chemicals currently produced from fossil carbon. In this paper we demonstrate a pathway from the renewable resource glucose to next generation biofuel isopentanol by pairing
Chiniquy, Jennifer +9 more
core +1 more source
Systematic review on spheroids from adipose‐derived stem cells: Spontaneous or artefact state?
Journal of Cellular Physiology, Volume 237, Issue 12, Page 4397-4411, December 2022., 2022 Our proposed model of spheroid isolation from liposuction fat. The tissue disintegration releases the pre‐existing spheroids as intact structures. This could be the ideal technique to culture cells in suspension because it avoids a preliminary adhesion isolation step and thus an upstream cell selection.
Anna Barbara Di Stefano +5 more
wiley +1 more source
The Structural Basis of Babesia orientalis Lactate Dehydrogenase
Frontiers in Cellular and Infection Microbiology, 2022 Glycolytic enzymes play a crucial role in the anaerobic glycolysis of apicomplexan parasites for energy generation. Consequently, they are considered as potential targets for new drug development. Previous studies revealed that lactate dehydrogenase (LDH)
Long Yu +14 more
doaj +1 more source
Mass conserved elementary kinetics is sufficient for the existence of a non-equilibrium steady state concentration [PDF]
, 2012 Living systems are forced away from thermodynamic equilibrium by exchange of mass and energy with their environment. In order to model a biochemical reaction network in a non-equilibrium state one requires a mathematical formulation to mimic this forcing.
Fleming, Ronan M. T., Thiele, Ines
core +2 more sources
hZIP1 Inhibits Progression of Clear Cell Renal Cell Carcinoma by Suppressing NF-kB/HIF-1α Pathway
Frontiers in Oncology, 2021 PurposeAccumulating literature has suggested that hZIP1 and HIF-1α play vital roles in the tumor process of clear cell renal cell carcinoma (ccRCC). However, the functional roles of hZIP1 and HIF-1α in ccRCC remain largely unknown.MethodsHIF-1α protein ...
Bo Zhan +4 more
doaj +1 more source
MEASUREMENT OF ANAEROBIC GLYCOLYSIS IN BRAIN AS RELATED TO POLIOMYELITIS [PDF]
Journal of Experimental Medicine, 1945 Experiments with mouse brain, homogenates show that the anaerobic glycolysis of such preparations can be increased tenfold by addition of appropriate coenzymes and phosphate esters. The previously reported alterations in anaerobic glycolysis during poliomyelitis, as measured with low activity preparations, are believed to be of doubtful value in so far
John M. Reiner +2 more
openaire +3 more sources
Metabolic changes during carcinogenesis: Potential impact on invasiveness [PDF]
, 2007 Successful adaptation to varying microenvironmental constraints plays a crucial role during carcinogenesis. We develop a hybrid cellular automation approach to investigate the cell–microenvironmental interactions that mediate somatic evolution of cancer ...
Gatenby, R. A. +4 more
core +1 more source
Mediators of Inflammation, 2014 To investigate the role of AEG-1 in glycolysis and tumorigenesis, we construct myc-AEG-1 expression vector and demonstrate a novel mechanism that AEG-1 may increase the activity of AMPK by Thr172 phosphorylation.
Hong-tao Song +5 more
doaj +1 more source