Results 51 to 60 of about 350,338 (294)

Phosphoproteomic Analysis of Xenopus laevis Reveals Expression and Phosphorylation of Hypoxia-Inducible PFKFB3 during Dehydration

iScience, 2020
Summary: Xenopus laevis tolerate dehydration when their environments evaporate during summer months. Protein phosphorylation has previously shown to regulate important adaptations in X. laevis, including the transition to anaerobic metabolism.
Liam J. Hawkins, Xiaoshuang Wang, Xiaomin Xue, Hui Wang, Kenneth B. Storey   +4 more
doaj   +1 more source

The Structural Basis of Babesia orientalis Lactate Dehydrogenase

Frontiers in Cellular and Infection Microbiology, 2022
Glycolytic enzymes play a crucial role in the anaerobic glycolysis of apicomplexan parasites for energy generation. Consequently, they are considered as potential targets for new drug development. Previous studies revealed that lactate dehydrogenase (LDH)
Long Yu, Long Yu, Qin Liu, Qin Liu, Wanxin Luo, Wanxin Luo, Junlong Zhao, Junlong Zhao, Junlong Zhao, Heba F. Alzan, Heba F. Alzan, Heba F. Alzan, Lan He, Lan He, Lan He   +14 more
doaj   +1 more source

Interrelationship between contractility, protein synthesis and metabolism in mantle of juvenile cuttlefish (Sepia officinalis) [PDF]

, 2019
Young juvenile cuttlefish (Sepia officinalis) can grow at rates as high as 12% body weight per day. How the metabolic demands of such a massive growth rate impacts muscle performance that competes for ATP is unknown.
Bamford, Bartol, Biolo, Capaz, Carter, Dizon, Driedzic, Forsythe, Fraser, Gibala, Grieshaber, Gäde, Johansen, Kitasato, Lamarre, Lamarre, Lamarre, Langer, Layland, Lewbart, Losito, Martínez-Quintana, McCully, Melzner, Milligan, Moltschaniwskyj, Nakamura, Okamoto, O’Dor, O’Dor, Phillips, Pörtner, Ruff, Sandow, Seibel, Seibel, Sepp, Shiels, Short, Speers-Roesch, Storey, Sykes, Sykes, Sykes, Sykes, Trueman, van Os, Wong, Wong, Xu   +49 more
core   +1 more source

hZIP1 Inhibits Progression of Clear Cell Renal Cell Carcinoma by Suppressing NF-kB/HIF-1α Pathway

Frontiers in Oncology, 2021
PurposeAccumulating literature has suggested that hZIP1 and HIF-1α play vital roles in the tumor process of clear cell renal cell carcinoma (ccRCC). However, the functional roles of hZIP1 and HIF-1α in ccRCC remain largely unknown.MethodsHIF-1α protein ...
Bo Zhan, Xiao Dong, Yulin Yuan, Zheng Gong, Bohan Li   +4 more
doaj   +1 more source

NAD(P)H fluorescence lifetime imaging of live intestinal nematodes reveals metabolic crosstalk between parasite and host

Scientific Reports, 2022
Infections with intestinal nematodes have an equivocal impact: they represent a burden for human health and animal husbandry, but, at the same time, may ameliorate auto-immune diseases due to the immunomodulatory effect of the parasites.
Wjatscheslaw Liublin, Sebastian Rausch, Ruth Leben, Randall L. Lindquist, Alexander Fiedler, Juliane Liebeskind, Ingeborg E. Beckers, Anja E. Hauser, Susanne Hartmann, Raluca A. Niesner   +9 more
doaj   +1 more source

Genome-wide association study reveals that enolase gene OsEE1 regulates coleoptile elongation in rice under anaerobic conditions

Crop Journal
Submergence can induce anaerobic stress on germinating seedlings in direct seeded rice paddy fields, limiting the practice of direct seeding. Longer coleoptiles improves the anaerobic tolerance of rice seedlings under submerged conditions.
Dandan Li, Kai Liu, Ling Su, Jinrui Li, Yuanyuan Guo, Tao Guo, Hong Liu, Dehua Rao   +7 more
doaj   +1 more source

INDUCTION OF ANAEROBIC PROCESSES IN BAIKAL ENDEMICS EULIMNOGAMMARUS VITTATUS (DYB.) AND E. VERRUCOSUS (DYB.) (AMPHIPODA, CRUSTACEA) [PDF]

Journal of Stress Physiology & Biochemistry, 2006
The data confirming the ability of Baikalian endemic species Eulimnogammarus vittatus (Dyb.) and E. verrucosus (Dyb.) to activate anaerobic glycolysis under hypoxia are presented. The differences in the degree and the rate of lactic acid accumulation and
Timofeyev M.A., Kirichenko K.A., Rokhin A.V., Bedulina D.S., Chernyshova K.P., Pobezhimova T.P.   +5 more
doaj  

ATP and Lactate Quantification

Bio-Protocol, 2013
Cells use glucose to generate energy by two different metabolic processes: lactic fermentation and aerobic respiration. In the first common series of reactions, glucose is converted into pyruvate.
Isaline Rowe, Marco Chiaravalli, Alessandra Boletta   +2 more
doaj   +1 more source

Heterogeneity and proliferation of invasive cancer subclones in game theory models of the Warburg effect [PDF]

, 2015
OBJECTIVES: The Warburg effect, the switch from aerobic energy production to anaerobic glycolysis, promotes tumour proliferation and motility by inducing acidification of the tumour microenvironment.
Archetti, Archetti, Archetti, Archetti, Archetti, Archetti, Bach, Basanta, Basanta, Basanta, Bergers, Bhujwalla, Buchler, Casciari, Feron, Gambhir, Gatenby, Gatenby, Gatenby, Gatenby, Gillies, Griffiths, Hanahan, He, Ibrahim Hashim, Ibrahim Hashim, Kelloff, Kianercy, Kunkel, Lardner, Martin, Martin, Maynard Smith, Mochiki, Park, Patel, Pauwels, Perc, Postovit, Postovit, Rajendran, Robey, Rohzin, Rubin, Schornack, Semenza, Shi, Silva, Smallbone, Smallbone, Sonveaux, Tomlinson, Tomlinson, Warburg, Williams, Wojtkowiak   +55 more
core   +1 more source

The anaerobic threshold: 50+ years of controversy

Journal of Physiology, 2020
The anaerobic threshold (AT) remains a widely recognized, and contentious, concept in exercise physiology and medicine. As conceived by Karlman Wasserman, the AT coalesced the increase of blood lactate concentration ([La−]), during a progressive exercise
D. Poole, H. Rossiter, G. Brooks, L. Gladden   +3 more
semanticscholar   +1 more source