Results 161 to 170 of about 377,158 (236)

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

Allergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan, Xufeng Qu, Carmen Camarena, Araba Abaidoo‐Myles, Parth Naik, Jeremy Allegood, Ankit Kumar, Mihir Pokhriyal, Joseph C. Lownik, Matthew P. Zellner, Grayson W. Way, Jinze Liu, Lauren Ashley Cowart, Stephanie C. Eisenbarth, Joseph W. Landry, Daniel H. Conrad, Rebecca K. Martin   +16 more
wiley   +1 more source

Anastomotic Failure Is Not Affected by Anastomotic Technique in Minimally Invasive Two‐Stage Oesophagectomy

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The choice of anastomotic technique in minimally invasive oesophagectomy (MIO) may influence postoperative morbidity and long‐term outcomes. The primary aim of our study is to determine whether circular (CS) or linear‐stapled (LS) anastomosis is associated with anastomotic complications following MIO.
L. Vu, C. Cabalag, L. Ng, B. Choo, A. Hardley, S. Kariyawasam   +5 more
wiley   +1 more source

The diversity of terminal electron acceptors across eukaryotes. [PDF]

Trends Biochem Sci
Midha AD, Jain IH.
europepmc   +1 more source

Fetal heart rate patterns associated with acidemia at fetal blood sampling during labor—An observational study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
The Swedish fetal heart rate (FHR) classification from 2017 identifies most FHR patterns associated with fetal acidemia as non‐normal, according to fetal blood sampling (FBS) in immediate connection to the ongoing FHR pattern. However, long‐standing FHR patterns with non‐repetitive decelerations of the types severe variable and late warrant increased ...
Erika Gyllencreutz, Klara Gröndal, Desiré Malm, Kari Johansson, Malin Holzmann   +4 more
wiley   +1 more source

Clinical Conditions Associated With Elevated Lactate Levels in Hospitalized Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim Lactate is included in adult septic shock criteria, but its role in paediatric sepsis is unclear. Recent guidelines propose lactate thresholds, though supporting evidence is limited. We aimed to identify conditions associated with elevated lactate in children and determine where levels are highest.
Eveliina Kuitunen, Ilari Kuitunen, Miika Arvonen, Marjo Renko   +3 more
wiley   +1 more source

Drug development targeting the mitochondrial respiratory chain of Sparganum proliferum: Initial biochemical and drug discovery insights into the enigmatic helminth parasite. [PDF]

PLoS Negl Trop Dis
Enkai S, Nakano Y, Koyanagi M, Arimura Y, Kanuka H, Ishiwata K.   +5 more
europepmc   +1 more source

Assessment of viral pathogen removal across wastewater treatment stages in a swine processing facility

Australian Veterinary Journal, EarlyView.
A swine abattoir wastewater treatment system in Queensland, Australia, was monitored over 6 months to assess the effectiveness of a pond‐based treatment system for the removal of viruses prior to irrigation reuse. Four viruses were tracked through the facility, from points of entry to the final treated effluent, to identify major sources of viral ...
W Ahmed, M Gebrewold, WJM Smith, K Richards, SL Simpson   +4 more
wiley   +1 more source

Genome-resolved insights into hydrocarbon-transforming and nitrate-reducing microbial communities from deep petroleum reservoir cores of the Nashpa Oil Field, Pakistan. [PDF]

Front Microbiol
Tayyaba S, Amin A, Zulfiqar S, Ahmed I.
europepmc   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

Evolution of Bacterial Yield and Antimicrobial Resistance in Chronic Rhinosinusitis Patients in a Dedicated Sinus Centre

Clinical Otolaryngology, EarlyView.
ABSTRACT Background Antibiotics are frequently prescribed for acute exacerbations of chronic rhinosinusitis (CRS). However, antimicrobial resistance presents a challenge for the ongoing and future management of CRS patients. Objective This study aims to examine the current and past microbiological yield and antimicrobial resistance profile in a ...
Timoleon Siempis, Zhu Yeap, Shifa Ali, Carl M. Philpott   +3 more
wiley   +1 more source