Results 91 to 100 of about 27,150 (219)

Anakinra in mutation-negative CINCA syndrome

Clinical Rheumatology, 2006
Peer ...
Callejas-Rubio, J. L., Oliver, Francisco Javier, Martín, J., Ortego-Centeno, N.   +3 more
openaire   +3 more sources

The Dental Status of Patients Taking Common Biologic Agents: A Single‐Center Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Objectives Despite expanding use and medical applications, little is known about the impact of biologic agents (BAs) on dental treatment. The aim of this study was to investigate the dental status of patients on common classes of BAs to understand treatment needs and use in this population.
Shivani Shah, Nila Veerabagu, Nana A. A. Essel, Neda Mahjour, Katherine France   +4 more
wiley   +1 more source

A systems pharmacology workflow with experimental validation to assess the potential of anakinra for treatment of focal and segmental glomerulosclerosis.

PLoS ONE, 2019
Focal and Segmental Glomerulosclerosis (FSGS) is a severe glomerulopathy that frequently leads to end stage renal disease. Only a subset of patients responds to current therapies, making it important to identify alternative therapeutic options.
Michael Boehm, Eva Nora Bukosza, Nicole Huttary, Rebecca Herzog, Christoph Aufricht, Klaus Kratochwill, Christoph A Gebeshuber   +6 more
doaj   +1 more source

Continuous Intravenous Anakinra Infusion to Calm the Cytokine Storm in Macrophage Activation Syndrome

ACR Open Rheumatology, 2020
Objective The objective of this study was to report the benefit of a therapeutic approach consisting of intravenous (IV) continuous anakinra (recombinant human interleukin‐1 receptor antagonist) infusions in treating severely ill adult patients with ...
Luke Adam Monteagudo, Aaron Boothby, Elie Gertner   +2 more
doaj   +1 more source

Acrodermatitis continua of Hallopeau: clinical perspectives. [PDF]

, 2019
Acrodermatitis continua of Hallopeau (ACH) is a rare, sterile pustular eruption of one or more digits. The condition presents with tender pustules and underlying erythema on the tip of a digit, more frequently arising on a finger than a toe.
Beck, Kristen M, Bhutani, Tina, Liao, Wilson, Ly, Karen, Smith, Mary Patricia, Thibodeaux, Quinn   +5 more
core  

Development of a peptide-siRNA nanocomplex targeting NF- κB for efficient cartilage delivery [PDF]

, 2019
Delivery of therapeutic small interfering RNAs (siRNAs) in an effective dose to articular cartilage is very challenging as the cartilage dense extracellular matrix renders the chondrocytes inaccessible, even to intra-articular injections. Herein, we used
Akk, Antonina, Duan, Xin, Pan, Hua, Pham, Christine T. N., Rai, Muhammad Farooq, Sandell, Linda J., Wickline, Samuel A., Yan, Huimin   +7 more
core   +3 more sources

Progressive Soft Tissue Swelling in a Pediatric Patient Leading to the Diagnosis of Fibrodysplasia Ossificans Progressiva: A Case Report

Pediatric Dermatology, EarlyView.
ABSTRACT Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by progressive heterotopic ossification (HO) and congenital malformation of the great toes. This case describes a 5‐year‐old Caucasian girl who initially presented with painless neck and back swelling as well as severe limitation of movement in the neck and ...
Orhan Yilmaz, Loretta Fiorillo
wiley   +1 more source

Subcutaneous anakinra in the management of refractory MIS-C in France

Frontiers in Pediatrics
IntroductionMultisystemic inflammatory syndrome in children (MIS-C) is a therapeutic emergency and can lead to myocardial dysfunction (17%–75%) and heart failure (52%–53%).
Perrine Dusser, Alexandre Belot, Fanny Bajolle, Charlotte Kevorkian-Verguet, Ulrich Meinzer, Ulrich Meinzer, Frédéric Huet, Soizic Tiriau, Isabelle Kone-paut   +8 more
doaj   +1 more source

Failure of anti Interleukin-1 β monoclonal antibody in the treatment of recurrent pericarditis in two children

Pediatric Rheumatology Online Journal, 2020
Background Recurrent pericarditis (RP) is a complication (15–30%) of acute pericarditis with an unknown etiology. Treatment regimen consists of a combination of non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine, with the addition of ...
Sara Signa, Matteo D’Alessandro, Rita Consolini, Angela Miniaci, Marta Bustaffa, Chiara Longo, Maria A. Tosca, Martina Bizzi, Roberta Caorsi, Leonardo Oliveira Mendonça, Andrea Pession, Angelo Ravelli, Marco Gattorno   +12 more
doaj   +1 more source

Is exogenous administration of IL-1ra (anakinra) likely to induce severe depression? [PDF]

, 2010
International ...
Aspe, Gilles, Autret-Leca, Elisabeth, Guilmot, Jean-Louis, Jonville-Bera, Annie-Pierre, Magnant, Julie   +4 more
core   +3 more sources