Results 131 to 140 of about 31,486 (223)

Efficacy, safety and effect on gene expression profiling of anakinra in systemic-onset juvenile idiopathic arthritis: final results of a randomised, double-blind, placebo-controlled trial (ANAJIS) [PDF]

, 2008
Pierre Quartier, Florence Allantaz, Rolando Cimaz, Pascal Pillet, Olivier Richer, Marine Desjonquères, A. Duquesne, Claude Messiaen, Christophe Bardin, X Bossuyit, Anne Boutten, J Bienvenu, Véronique Ménoni, S Sotou-Bere, Bénédicte Neven, N Mahloui, A. Mogenet, Behrouz Kassaï, Damien Chaussabel, Jean‐Marc Tréluyer, JL Bresson, Paul Landais, Virginia Pascual   +22 more
openalex   +1 more source

Anakinra for dengue patients with hyperinflammation: protocol for a randomized double-blind placebo-controlled trial [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
Background Novel host-directed therapies are urgently needed for patients with dengue, particularly those at high risk of developing severe disease.
Angela McBride, Huynh Thi Le Duyen, Nguyen Thanh Phong, Truong Ngoc Trung, Sophie Yacoub, Ronald Geskus, Tran Bang Huyen, Evelyne Kestelyn, Dang Trong Thuan, Nguyen Thi My Linh, Tran Thi Dong Vien, Nguyen Thi Cam Huong, Phan Vinh Tho, Nguyen Minh Nguyet, Vo Thi My Hoa, Nguyen Lam Vuong, Phan Tu Qui, Dong Thi Hoai Tam, James Watson, Huynh Trung Trieu   +19 more
doaj   +1 more source

Cardiovascular Dysfunction in Polycystic Ovary Syndrome: Mitochondrial and Inflammatory Mechanisms

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder that significantly increases cardiovascular disease (CVD) risk in women. While insulin resistance and dyslipidemia are established contributors, growing evidence highlights mitochondrial dysfunction and chronic low‐grade inflammation as central drivers of cardiovascular ...
Olabimpe Caroline Badejogbin, Mary Olaoluwa Agunloye, Ojichukwuka Ebere Chijioke-Agu, Makinde Vincent Olubiyi, Success Oluwanifesimi Olugbuyiro, Olaniyi Azeez Soetan, Opeyemi Abel Bamgbose, Tobi Opeyemi Olaleye, Swaran J. S. Flora   +8 more
wiley   +1 more source

A large pericardial effusion and bilateral pleural effusions as the initial manifestations of Familial Mediterranean Fever [PDF]

, 2015
Familial Mediterranean Fever (FMF) is a condition characterized by recurrent febrile poly-serositis. Typical presentations of the disease include episodes of fever, abdominal pain and joint pains. Chest pain is a less common presentation.
Cassar Demarco, Daniela, Coleiro, Bernard, Mallia, Carmel, Mifsud, Simon, Schembri, Emma Louise   +4 more
core  

Glucocorticoids with low-dose anti-IL1 anakinra rescue in severe non-ICU COVID-19 infection: A cohort study

, 2020
Raphaël Borie, Laurent Savale, Antoine Dossier, Jade Ghosn, Camille Taillé, Benoît Visseaux, Kamel Jebreen, Abourahmane Diallo, Chloé Tesmoingt, Lise Morer, Tiphaine Goletto, Nathalie Faucher, L. Hajouji, Catherine Neukirch, Mathilde Phillips, S. Stélianides, Lila Bouadma, Solenn Brosseau, Sébastien Ottaviani, Johan Pluvy, Diane Le Pluart, Marie‐Pierre Debray, A. Raynaud-Simon, Diane Descamps, Antoine Khalil, Jean‐François Timsit, François-Xavier Lescure, V. Descamps, T. Papo, Marc Humbert, Bruno Crestani, Philippe Dieudé, Éric Vicaut, Gérard Zalcman, on behalf of Bichat & Kremlin-Bicêtre AP-HP COVID teams   +34 more
openalex   +1 more source

AB1059 A RANDOMIZED, PLACEBO-CONTROLLED STUDY OF ANAKINRA IN PATIENTS WITH STILL´S DISEASE [PDF]

, 2020
Laura E. Schanberg, Peter A. Nigrović, Adam Cooper, W. Winn Chatham, Shoghik Akoghlanian, Naresh Pal Singh, E. Rabinovich, Akaluck Thatayatikom, Alysha J. Taxter, Jonathan S. Hausmann, Milan Zdravković, S. Ohlman, H. Andersson, S. Cederholm, Margareta Wikén, Rayfel Schneider, Fabrizio De Benedetti   +16 more
openalex   +1 more source

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

Anakinra for severe forms of COVID-19 – Authors' reply [PDF]

, 2020
Gilles Hayem, Thomas Huet, Stéphane Jouveshomme, Hélène Beaussier, Gilles Châtellier, Jean‐Jacques Mourad   +5 more
openalex   +1 more source

The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira, Robson Xavier Faria, Wei Wang   +2 more
wiley   +1 more source

Rationale and study design for a phase I/IIa trial of anakinra in children with Kawasaki disease and early coronary artery abnormalities (the ANAKID trial)

, 2016
Adriana H. Tremoulet, Sonia Jain, Hanna Kim, Jane W. Newburger, Moshe Arditi, Alessandra Franco, Brookie M. Best, Jane C. Burns   +7 more
openalex   +1 more source