Results 131 to 140 of about 27,150 (219)

Current insights into pathogenesis and anti‐inflammatory treatment strategies for severe alcohol‐associated hepatitis: focus on neutrophil‐targeted therapies

Hepatology Research, Volume 55, Issue 6, Page 785-794, June 2025.
Abstract Alcohol‐associated hepatitis (AH) is the leading cause of liver‐related mortality, with severe alcohol‐associated hepatitis (SAH) showing a short‐term mortality rate of 20%–50% even in developed countries. Corticosteroids are the only evidence‐based pharmacologic treatment, but their efficacy is limited to short‐term survival, with 30%–40% of ...
Ryosuke Kasuga, Po‐Sung Chu, Takanori Kanai, Nobuhiro Nakamoto   +3 more
wiley   +1 more source

Transport study of interleukin-1 inhibitors using a human in vitro model of the blood-brain barrier

Brain, Behavior, & Immunity - Health, 2021
The proinflammatory cytokine Interleukin-1 (IL-1), with its two isoforms α and β, has important roles in multiple pathogenic processes in the central nervous system.
Elisabet O. Sjöström, Maxime Culot, Lisa Leickt, Mikael Åstrand, Erik Nordling, Fabien Gosselet, Christina Kaiser   +6 more
doaj  

Biologic treatments in rheumatoid arthritis and juvenile idiopathic arthritis [PDF]

, 2006
A number of biological approaches to the management of inflammtory arthropathies have been explored. These include the development of IL-1 receptor antagonists and TNF antagonists. Four biological agents are currently marketed in Europe.
Borg, Andrew A.
core  

Impact of A Multidisciplinary Team Discussion for Genetic Lung Fibrosis

Respirology, Volume 30, Issue 6, Page 523-532, June 2025.
ABSTRACT Background and Objective Approximately 30% of individuals diagnosed with familial pulmonary fibrosis (FPF) exhibit a pathogenic variant upon genetic analysis. We established a genetic Multidisciplinary Discussion (geneMDD) aimed to enhance expertise in diagnosing and managing FPF.
Giovanni Franco, Ibrahima Ba, Nadia Nathan, Cécile Guerin, Albane Lassus, Caroline Kannengiesser, Antoine Froidure, Effrosyni Manali, Vincent Bunel, Philippe Bonniaud, Diane Bouvry, Marie Pierre Debray, Pierre Antoine Juge, Ralph Epaud, Camille Louvrier, Aurélie Plessier, Flore Sicre de Fontbrune, Lidwine Wémeau‐Stervinou, Sylvain Marchand Adam, Alexandre Chabrol, Arnaud Maurac, Laurent Savale, David Montani, Caroline Raynal, Marina Konyukh, Arthur Mageau, Bruno Crestani, Vincent Cottin, Alix de Becdelièvre, Raphaël Borie, Respifil and OrphaLung   +30 more
wiley   +1 more source

Targeting inflammatory pathways in axial spondyloarthritis. [PDF]

, 2019
The triggers and pathogenesis of axial spondyloarthritis (axSpA) are not yet completely understood. However, therapeutic agents targeting tumor necrosis factor-α and interleukin-17 inflammatory pathways have proven successful in suppressing many of the ...
Furst, Daniel E, Louie, James S
core  

The trials of anakinra

The Lancet, 2004
Burls, A, Jobanputra, P
openaire   +4 more sources

Thinking Clearly with Anakinra

Transplantation and Cellular Therapy, 2023
openaire   +2 more sources

Intravenous anakinra for cytokine storm syndromes [PDF]

The Lancet Rheumatology, 2020
Mathieu Gerfaud-Valentin, Yvan Jamilloux, Yvan Jamilloux, Pascal Sève   +3 more
openaire   +3 more sources

Mullins' syndrome: a new gammopathy-related autoinflammatory syndrome resistant to anakinra [PDF]

, 2015
A.L. Manson, Arend, Gekowski, H.J. Longhurst, Haeffner-Cavaillon, J.D. Cavenagh, M.S. Buckland, Nashan, Okusawa, P.F.K. Yong, Rybojad, S. Grigoriadou, Schindler   +12 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source