Results 21 to 30 of about 22,540 (195)

Effect of in vitro and in vivo anakinra on cytokines production in Schnitzler syndrome. [PDF]

PLoS ONE, 2013
IL-1 receptor antagonist anakinra is usually highly efficient in Schnitzler syndrome (SS), a rare inflammatory condition associating urticaria, fever, and IgM monoclonal gammopathy.
David Launay, Virginie Dutoit-Lefevre, Emmanuel Faure, Olivier Robineau, Carine Hauspie, Vincent Sobanski, Eric Hachulla, Myriam Labalette, Pierre-Yves Hatron, Sylvain Dubucquoi   +9 more
doaj   +1 more source

Anakinra and MIS-C

, 2023
Statistical data on use of Anakinra in MIS ...
Andrea Taddio (14679391)
core   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Anakinra treatment in drug-resistant Behcet's disease: a case series.

, 2013
The study objective was to report treatment with an interleukin (IL)-1 receptor antagonist, anakinra, in patients with multiorgan Behcet's disease (BD).
Rigante D, Caso F, Bertoldi I, Punzi L, Borsari G, CANTARINI, LUCA, GALEAZZI, MAURO, Simonini G, Cimaz R., LUCHERINI, ORSO MARIA, Vitale A, FRANCESCHINI, ROSSELLA, FREDIANI, BRUNO, Scalini P, Dinarello CA   +14 more
core   +4 more sources

Covid-19: αντιφλεγμονώδης δράση του anakinra [PDF]

, 2021
Στόχος: Μελετήθηκε η πρόληψη της σοβαρής αναπνευστικής ανεπάρκειας (ΣΑΑ) σε ασθενείς με λοίμωξη κατώτερου αναπνευστικού από τον SARS-CoV-2, στους οποίους έγινε πρώιμη χορήγηση θεραπείας με anakinra, καθοδηγούμενη από την τιμή του suPAR (διαλυτός ...
Marantos Theodoros, Μάραντος Θεόδωρος   +1 more
core   +1 more source

Budget Impact Analysis of anakinra in the treatment of patients with Still’s Disease

Global & Regional Health Technology Assessment, 2020
Background: Anakinra, canakinumab and tocilizumab are all effective alternative treatment choice in patients with Still’s disease including both systemic juvenile idiopathic arthritis (SJIA) adult onset Still’s disease (AOSD) compared to canakinumab and ...
Roberto Ravasio, Roberto Giacomelli, Stefano Bianchi   +2 more
doaj   +1 more source

Anakinra reduces lung inflammation in experimental acute lung injury

Immunity, Inflammation and Disease, 2022
Introduction Acute respiratory distress syndrome (ARDS) is a severe form of acute lung injury (ALI) resulting in life‐threatening hypoxaemia. Although ARDS can be caused by a variety of pathogens or major trauma, it is best known as the major cause of ...
Paul Engeroff, Aude Belbézier, Antoine Monsel, David Klatzmann   +3 more
doaj   +1 more source

Protective effect of anakinra on audiovestibular function in a murine model of endolymphatic hydrops

Frontiers in Cellular Neuroscience, 2022
IntroductionMénière’s disease (MD), a common disease in the inner ear, is characterized by an increase in endolymph in the cochlear duct and vestibular labyrinth. The pathophysiology of the condition appears to be the immune response.
Na Zhang, Na Zhang, Na Zhang, Na Li, Na Li, Na Li, Siyue Wang, Siyue Wang, Siyue Wang, Wandi Xu, Wandi Xu, Wandi Xu, Jiahui Liu, Jiahui Liu, Jiahui Liu, Yafeng Lyu, Yafeng Lyu, Yafeng Lyu, Xiaofei Li, Xiaofei Li, Xiaofei Li, Yongdong Song, Yongdong Song, Yongdong Song, Ligang Kong, Ligang Kong, Ligang Kong, Yalan Liu, Yalan Liu, Yalan Liu, Jia Guo, Jia Guo, Jia Guo, Zhaomin Fan, Zhaomin Fan, Zhaomin Fan, Daogong Zhang, Daogong Zhang, Daogong Zhang, Haibo Wang, Haibo Wang, Haibo Wang   +41 more
doaj   +1 more source

Prediction of Survival by IL-6 in a Randomized Placebo-Controlled Trial of Anakinra in COVID-19 Cytokine Storm

Viruses, 2023
(1) Background: Some severe COVID-19 patients develop hyperinflammatory cytokine storm syndrome (CSS). We assessed the efficacy of anakinra added to standard of care (SoC) in hospitalized COVID-19 CSS patients.
Lesley E. Jackson, Nitasha Khullar, Timothy Beukelman, Chris Chapleau, Abhishek Kamath, Randy Q. Cron, Walter Winn Chatham   +6 more
doaj   +1 more source

Outcomes of MIS-C patients treated with anakinra: a retrospective multicenter national study

Frontiers in Pediatrics, 2023
BackgroundThe treatment of multisystem inflammatory syndrome in children unresponsive to first-line therapies (IVIG and/or steroids) is challenging. The effectiveness of IL-1 receptor antagonist, anakinra, is debated.Patients and methodsWe conducted an ...
Francesco Licciardi, Carlotta Covizzi, Marta Dellepiane, Nicole Olivini, Maria Vincenza Mastrolia, Andrea Lo Vecchio, Viviana Monno, Maria Tardi, Angela Mauro, Maria Alessio, Giovanni Filocamo, Marco Cattalini, Andrea Taddio, Roberta Caorsi, Gian Luigi Marseglia, Francesco La Torre, Andrea Campana, Gabriele Simonini, Angelo Ravelli, Davide Montin   +19 more
doaj   +1 more source