Results 31 to 40 of about 31,861 (267)
National Institute for Clinical Excellence and its value judgments [PDF]
, 2004 The National Institute for Clinical Excellence (NICE) offers health professionals in England and Wales advice on providing NHS patients with the highest attainable standards of care.
Culyer, A.J., Rawlins, M.D.
core +2 more sources
Viruses, 2023 (1) Background: Some severe COVID-19 patients develop hyperinflammatory cytokine storm syndrome (CSS). We assessed the efficacy of anakinra added to standard of care (SoC) in hospitalized COVID-19 CSS patients.
Lesley E. Jackson +6 more
doaj +1 more source
Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study
Critical Care, 2020 Background A subset of critically ill COVID-19 patients develop a hyperinflammatory state. Anakinra, a recombinant interleukin-1 receptor antagonist, is known to be effective in several hyperinflammatory diseases.
Emma J. Kooistra +11 more
doaj +1 more source
Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]
, 2013 Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer +12 more
core +1 more source
Outcomes of MIS-C patients treated with anakinra: a retrospective multicenter national study
Frontiers in Pediatrics, 2023 BackgroundThe treatment of multisystem inflammatory syndrome in children unresponsive to first-line therapies (IVIG and/or steroids) is challenging. The effectiveness of IL-1 receptor antagonist, anakinra, is debated.Patients and methodsWe conducted an ...
Francesco Licciardi +19 more
doaj +1 more source
Reimann's "Habitual Hyperthermia" Responding to Hormone Therapy. [PDF]
, 2016 A 25-year-old woman presented with fever of unknown origin, exhibiting malaise and low-grade fevers in evenings. These fevers exhibited a pattern of starting mid-menstrual cycle with resolution around the onset of menses, matching a pattern of "habitual ...
Currier, Judith S, Yang, Otto O
core +2 more sources
BiologyRheumatoid arthritis and periodontitis are comorbidities that share mutual pathways. IL-1β is a pro-inflammatory cytokine that plays a crucial role in both diseases.
Elizabeth Steemers +4 more
doaj +1 more source
Anakinra for infants under six months with Kawasaki disease and coronary artery lesions: a multicenter case series and literature review. [PDF]
Pediatr Rheumatol Online JInguscio G +9 more
europepmc +2 more sources
Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor treated CML stem cells [PDF]
, 2016 Treatment of chronic myelogenous leukemia (CML) with BCR-ABL tyrosine kinase inhibitors (TKI) fails to eliminate leukemia stem cells (LSC). Patients remain at risk for relapse, and additional approaches to deplete CML LSC are needed to enhance the ...
Agarwal, Puneet +9 more
core +1 more source