Results 191 to 200 of about 395,234 (289)

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): baseline data from day surgery practice in the UK

open access: yesAnaesthesia, Volume 81, Issue 4, Page 477-488, April 2026.
Summary Introduction Most patients undergoing elective surgery in the UK are discharged from hospital on the same day. Despite this, there is a lack of UK patient‐centred outcome measures relating to quality of recovery, pain and analgesic use. The POPPY study was a UK‐wide prospective, observational study measuring short‐ and longer‐term patient ...
Martha Belete   +2177 more
wiley   +1 more source

Mapping the Prevalence of Lynch Syndrome in the Ceará—Northeast of Brazil

open access: yesClinical Genetics, Volume 109, Issue 4, Page 630-638, April 2026.
Distribution of pathogenic variants associated with Lynch syndrome across Brazil, with a particular emphasis on the state of Ceará. The illustration highlights the most frequently reported MMR genetic variants in Brazil and provides a magnified view of Ceará, where three novel variants were identified in the APC, SMAD4, and MSH6 genes within specific ...
Maria Claudia dos Santos Luciano   +8 more
wiley   +1 more source

The Role of Human Papillomavirus E6 Oncoprotein as a Biomarker in Anal Cancer Screening in Persons Living with HIV. [PDF]

open access: yesCancer Epidemiol Biomarkers Prev
Faria F   +10 more
europepmc   +1 more source

Vaccines at the Heart of Hepatitis Elimination: Insights From the ESCMID Study Group for Viral Hepatitis (ESGVH)

open access: yesLiver International, Volume 46, Issue 4, April 2026.
ABSTRACT The global elimination of viral hepatitis by 2030 remains an ambitious goal that hinges not only on diagnostics and therapeutics but fundamentally on the strategic use and continued innovation of vaccines. The ESCMID Study Group for Viral Hepatitis (ESGVH) convened to examine the role of vaccination as the cornerstone of hepatitis prevention ...
Oana Săndulescu   +5 more
wiley   +1 more source

Anal Cancer Incidence Rates Among Men and Women With and Without HIV in South Africa. [PDF]

open access: yesOpen Forum Infect Dis
Fernández Villalobos NV   +9 more
europepmc   +1 more source

Modulation of Tau Protein Neurotoxic Hallmarks by Novel σ1R Agonists/HDAC Inhibitor Dual‐Acting Compounds

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
This study explores the development of dual‐acting compounds combining σ1R agonists and histone deacetylase inhibitors (HDACi). Key findings include compound 2d and 3a's high affinity for σ1R and favorable pharmacokinetic profile and an in vivo determined σ1R agonist profile by reversing the effect of the σ1R antagonist BD‐1063.
Antonino N. Fallica   +16 more
wiley   +1 more source

Consecutive (Pseudo‐)Four‐Component Synthesis of Meta‐ and Ortho‐Biaryl Triarylamines with Tunable Emission and Redox Properties

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 9, 2 March 2026.
The combination of Suzuki and Buchwald–Hartwig coupling in (pseudo‐)four‐component reactions paves an efficient one‐pot route to twisted, redox‐active triarylamine (TAA) emitters. Biaryl substitution patterns and para‐substituents serve as key levers for tuning redox potentials, as well as absorption and emission energies, complemented and, by time ...
Regina Kohlbecher   +5 more
wiley   +1 more source

Anal cancer impact among people with HIV infection - a matched cohort study. [PDF]

open access: yesEcancermedicalscience
de Almeida Robatto AA   +17 more
europepmc   +1 more source

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