Results 51 to 60 of about 151,157 (179)

Spectrum of Congenital Malformations in Sex Chromosome Tetrasomies and Pentasomies: A Systematic Review

Andrology, EarlyView.
ABSTRACT Sex chromosome aneuploidies represent a heterogeneous group of chromosomal conditions, in which phenotypic complexity generally increases with the number of supernumerary sex chromosomes. While Turner syndrome and sex chromosome trisomies are relatively well characterized, less is known about congenital malformations in sex chromosome ...
Anna Colding, Jannie Traberg, Inger Lily Hjuler Dorf, Anne Skakkebæk   +3 more
wiley   +1 more source

Total lateral sphincterotomy for anal fissure

, 2004
Background and aims. Initial experience with the posterior sphincterotomy for treating anal fissures was unsatisfactory, with a significant rate of recurrences and anal incontinence.
MICCINI, MICHELANGELO, BETTELLI, ELIA, CASSINI, Diletta, BROZZETTI, Stefania, Gianluca Mazzoni, TOCCHI, Adriano   +5 more
core   +1 more source

Value of 3D‐High Resolution Anorectal Manometry Before and After Fistulotomy for Simple Perianal Fistulas: A Prospective Cohort Study

ANZ Journal of Surgery, EarlyView.
In this prospective cohort study, 3D‐high resolution anorectal manometry provided detailed regional pressure assessment but failed to predict postoperative continence deterioration after fistulotomy for simple perianal fistulas. These findings highlight the need for a continence assessment tool that better distinguishes true fecal incontinence from ...
Justin Y. van Oostendorp, Pieter van Hagen, Ruben Veldkamp, Lisette Dekker, Ingrid J. M. Han‐Geurts   +4 more
wiley   +1 more source

A Clinical Study of Fissure in Ano at Tertiary Center in North Telangana [PDF]

Perspectives In Medical Research, 2018
Introduction: An anal fissure is a distressing problem faced by a patient. It is one of the commonest painful anal condition. It is relatively simple to treat with rewarding results.
Y Narendra1 , K Naveen Kumar2 , Samir Ahmad3
doaj  

COMPARISON OF LATERAL ANAL SPHINCTEROTOMY WITH 0.2% GTN IN CHRONIC ANAL FISSURE

Pakistan Armed Forces Medical Journal, 2018
Objective: To compare fissure healing and complications in chronic anal fissure with use of lateral anal sphicterotomy and 0.2% GTN. Study Design: Randomized controlled trial. Place and Duration of Study: Combined Military Hospital Rawalpindi & Combined
Muhammad Salim Akhtar, Muhammad Qasim Butt, Samiya Razzaq, Sadaf Usman, Muhammad Usman Akhtar   +4 more
doaj   +4 more sources

Botulinum toxin injection versus lateral internal sphincterotomy in the treatment of chronic anal fissure: a non-randomized controlled trial

BMC Gastroenterology, 2004
Background Although lateral internal sphincterotomy is the gold-standard treatment for chronic anal fissure, intrasphincteric injection of botulinum toxin seems to be a reliable new option. The aim of this non-randomized study is to compare the effect of
Ulusoy Nefise B, Kalaycı Cem, İmeryüz Neşe, Gültekin Yücel, Memişoğlu Kemal, Giral Adnan, Tözün Nurdan   +6 more
doaj   +1 more source

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding, Qing Liu, Qiong Luo, Xiaojun Yao, Xingxing Fan   +4 more
wiley   +1 more source

Comparative Study of Lateral Internal Sphincterotomy versus Local 0.4% Glyceryl Trinitrate Ointment for the Treatment of Chronic Anal Fissure

Journal of Bahria University Medical and Dental College
Objectives: To compare the outcomes of “Lateral Internal Sphincterotomy (LIS)” versus local “0.4% Glyceryl Trinitrate (GTN)” ointment for the treatment of chronic anal fissure.
Utban Ali Shah, Tabish Iqbal, Khurram Sarafaraz, Muhammad Idress, Momina Javed, Jawad Hamed   +5 more
doaj   +1 more source

Same‐night PrEP in community care: The Nightcafé model for male and transgender sex workers

HIV Medicine, EarlyView.
Abstract Introduction Despite high risk of HIV infection, uptake of pre‐exposure prophylaxis (PrEP) remains limited among male and transgender sex workers (MSW and TSW), and data on tailored interventions to improve access are scarce. The Nightcafé programme addresses this gap by offering low‐threshold PrEP provision in a community‐centred setting ...
Elena Heizmann, Andrea Farnham, Christian Grolimund, Jorge Flores Real, Paul Halm, Veronika Braig, Hadrien Komaromi, Giulietta Mila Laffers, Jan Fehr, Benjamin Hampel   +9 more
wiley   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source